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System for automated high-speed imaging and genetic manipulation of C. elegans on agar media
TS-065892 — The Need The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …
  • College: College of Engineering (COE)
  • Inventors: Fang-Yen, Christopher "Chris"; Alhalbi, Serge; Li, Zihao
  • Licensing Officer: Randhawa, Davinder

Sacrificial Layer to Facilitate Welding of Thin Foils
TS-065430 — Cost-effective method to prevent damaged electrodes when welding thin foils.
Manufacturing of automotive lithium-ion batteries and battery packs is attracting growing attention with the driving demands of electric vehicles. During battery assembly, multi-layers of metal films, functioning as anodes, cathodes, or bus-bars are welded together. Achieving satisfying weld quali…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xun; Kwon, Ho; Shah, Umair
  • Licensing Officer: Zinn, Ryan

Streamlined Die Design Approach for Friction Stir Extrusion
TS-065428 — The Ohio State University researchers led by Dr. Rajiv Shivpuri have developed a die design approach for friction stir extrusion that optimizes metal flow to improve production efficiencies.
Friction stir extrusion (FSE) is a variation of friction stir processing that enables the hot extrusion of metal profiles from billet or other precursor material without preheating. This process saves significant thermal energy over conventional metal extrusion processes and can impart favorable …
  • College: College of Engineering (COE)
  • Inventors: Shivpuri, Rajiv
  • Licensing Officer: Zinn, Ryan

Self-filling Friction Stir Welding Processing
TS-065427 — The Ohio State University has developed a novel self-filling friction stir welding tool that eliminates keyhole defects caused by tool pin retraction.
Friction stir welding (FSW) and friction stir processing (FSP) are solid-state processes that utilize the heat generated from a rotating pin tool to soften the base metals for fusion and repair, respectively. However, keyhole defects are inevitably left after retracting the tool pin, which can ge…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xun
  • Licensing Officer: Zinn, Ryan

Containment System for Heating and Off-Gassing
TS-065424 — Due to environmental concerns and the decreasing supply of fossil fuels, there is substantial demand for nuclear-based energy production. Nuclear energy now provides about 10% of the world's electricity from about 440 power reactors and is the second largest source of low-carbon power. In addition, over 50 smaller countries utilize nuclear energy in about 220 research-size reactors. These reactors are used to produce medical and industrial isotopes and several other purposes.
It is essential to meet the safeguard requirements in liquid-fueled molten salt reactors, fuel salt transportation, and fuel cycle processes and to develop effective methods for measuring and monitoring the mass of molten fuel salt or coolant salt. However, due to the complex and dynamic nature o…
  • College: College of Engineering (COE)
  • Inventors: Van Zile, Matthew; Cao, Lei Raymond; Kauffman, Andrew
  • Licensing Officer: Zinn, Ryan

Highly Efficient Light Olefin Selectivity & Production Process
TS-065422 — Light olefins, such as ethylene and propylene, are essential building blocks in the petrochemical industry and have a wide range of uses in various applications. The most common uses for olefins include polymers, chemical intermediates, solvents, rubber, and nanomaterials, among others.
Although Light olefins are used globally in many products, the catalytic processes to produce them are energy intensive with a large carbon footprint and the production of greenhouse gases and water pollution. As a result, substantial efforts are being made in the industry to develop more sustain…
  • College: College of Engineering (COE)
  • Inventors: Ozkan, Umit; Gunduz, Seval; Kim, Jaesung
  • Licensing Officer: Zinn, Ryan

Revolutionizing Hydrogen Production and CO2 Capture for a Sustainable Future
TS-065143 — The Need: In the face of pressing environmental concerns and the imperative for sustainable energy solutions, there arises a critical commercial need for systems and methods that can efficiently produce hydrogen (H2) while simultaneously capturing and converting carbon dioxide (CO2) emissions. Trad…
  • College: College of Arts & Sciences
  • Inventors: Baker, Lawrence "Robert"
  • Licensing Officer: Panic, Ana

Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
  • College: College of Arts & Sciences
  • Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
  • Licensing Officer: Panic, Ana

Automatic Mechanical Assembly Loops/Stacks Detection
TS-064578 — This software solution revolutionizes the process of tolerance stack analysis in mechanical assemblies. It automatically detects and extracts tolerance stacks as the foundational step for precise tolerance analysis and schema generation.
This software solution revolutionizes the process of tolerance stack analysis in mechanical assemblies. It automatically detects and extracts tolerance stacks as the foundational step for precise tolerance analysis and schema generation. The Need Analyzing tolerance stacks in mechanical assembl…
  • College: College of Engineering (COE)
  • Inventors: Haghighi, Payam; Shah, Jami
  • Licensing Officer: Randhawa, Davinder

Variable Stiffness Robotic Gripper Based on Layer Jamming
TS-064318 — Introducing cutting-edge soft robotic grippers featuring variable stiffness through positive pressure layer jamming, revolutionizing object manipulation in diverse applications. For a closely related technology, please visit https://oied.osu.edu/find-technologies and type "T2020-092" in the search field.
Automation using robotics has taken many forms including, but not limited to, automotive manufacturing, transportation of good in shipping warehouses, and the delicate handling of wafers in semiconductor plants. In many of these applications grippers and end-of-arm-tools (EOAT’s) are incorpo…
  • College: College of Engineering (COE)
  • Inventors: Su, Haijun; Crowley, George; Zeng, Xianpai
  • Licensing Officer: Zinn, Ryan

Co-Axial Contained Electrospray Ionization Platform for Mass Spec.
TS-064299 — Mass spectrometry (MS) is used across a wide range of applications involving analytical chemistry. Various MS techniques, often coupled with liquid chromatography (LC), allow for detection of various chemical analytes, from drug metabolites, pesticides, food adulterants, and natural product extracts…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Burris, Benjamin "Ben"; Grooms, Alex; Heiss, Derik; Kulyk, Dmytro
  • Licensing Officer: Dahlman, Jason "Jay"

Column-free Purification of Recombinant Proteins
TS-064270 — Large-scale recombinant proteins in Gram-negative bacteria (i.e., E. coli) are of significant interest in recombinant protein/enzyme production. These proteins exhibit wide-ranging applications, including food and beverages, conversion of carbohydrates into fuel ethanol or biodiesel, components for …
  • College: College of Arts & Sciences
  • Inventors: Gopalan, Venkat
  • Licensing Officer: Panic, Ana

Apparatus and Method for Enhanced Determination of Optimal Operational Separation for Collaborative Robotic Systems
TS-063983 — Collaborative robotic systems, often referred to as cobots, represent a transformative advancement in industrial automation. Unlike traditional robots that are typically large, heavy, and designed to work in insolation behind safety barriers, cobots are designed to work alongside human operators c…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Tkach, Chris
  • Licensing Officer: Zinn, Ryan

Endoscopic additive manufacturing of biomaterials
TS-063919 — An articulating end effector for additive manufacturing that utilizes robot-assisted endoscopic surgery to implant synthetic tissues at local defects through “keyhole” incisions in patients. This innovative technology T2019-145 is part of a portfolio that also includes T2017-363. To learn more about both technologies, please visit https://oied.osu.edu/find-technologies and search using the phrase: Endoscopic additive manufacturing of biomaterials.
Robot-assisted surgery, tissue engineering, and additive manufacturing (AM) are emerging techniques in healthcare. Currently AM is used to develop synthetic tissues and organs, but open surgery is typically used to implant these scaffolds within the patient. This invasive procedure can subject pat…
  • College: College of Engineering (COE)
  • Inventors: Hoelzle, David; Asghari Adib, Ali; D'Souza, Desmond; Mansour, Daniel; Simeunovic, Andrej
  • Licensing Officer: Zinn, Ryan

In situ damage free etching of Ga2O3 using Ga flux for fabricating high aspect ratio 3D structures
TS-062975 — With a high theoretical breakdown field strength, β-Ga2O3 has the potential to be useful in power switching and high frequency power amplifying devices. For any device technology to be competitive, damage free etching techniques are necessary. All current dry etching recipes in β-Ga2O3 h…
  • College: College of Engineering (COE)
  • Inventors: Rajan, Siddharth; Fiedler, Andreas; Kalarickal, Nidhin Kurian
  • Licensing Officer: Zinn, Ryan

Automated Endotracheal Intubation
TS-062900 — This cutting-edge technology redefines the intubation process by guiding the endotracheal tube into the airway with exceptional precision.
The Need Intubation is a critical medical procedure used to assist patients with breathing difficulties, executed through the insertion of an endotracheal tube (ET) into the windpipe. With over 313 million annual intubation procedures worldwide, ensuring first-pass success and minimizing complicati…
  • College: College of Engineering (COE)
  • Inventors: Ruegsegger, Mark; Elsayed-Awad, Hamdy; Hopping, Ethan; Lopez Vogler, Christian; Miles, Tim; Peiffer, Jordan
  • Licensing Officer: Bhatti, Hamid

pH-sensitive inhibitor release system for corrosion protection
TS-062835 — Coatings are broadly used to protect metallic structures from corrosion. However, aggressive acidic and alkaline conditions can both develop locally on the coated metal surface due to corrosion, leading to the failure of the coated structure. Commonly used smart coatings use a timed release of spe…
  • College: College of Engineering (COE)
  • Inventors: Li, Chao; Frankel, Gerald "Jerry"; Guo, Xiaolei
  • Licensing Officer: Zinn, Ryan

Heteroatom doped Carbon Nanostructures for Electrocatalytic Chlorine and Bromine Production
TS-062692 — Chlorine is used in production of many products, such as many polymers like polyvinyl chloride, polyurethanes and chloroaromatics. It is also used extensively in pharmaceuticals, pesticides, fiber optics, hypochlorite bleaches, and other commodities. However, the current method of producing chlori…
  • College: College of Engineering (COE)
  • Inventors: Ozkan, Umit; Jain, Deeksha; Mamtani, Kuldeep
  • Licensing Officer: Zinn, Ryan

Novel Efficient Butanol Production without CO2 Emission
TS-062607 — Chemicals and fuels from renewable resources have gained global interest due to environmental issues, climate change, oil price and supply volatility, and decreasing nonrenewable fossil fuel sources. Butanol is a biofuel alternative that can provide a higher heating value, lower volatility, polarity…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"
  • Licensing Officer: Panic, Ana

Method and device for determining virus titer by surface enhanced Raman scattering
TS-062346 — The ability to rapidly identify and determine virus titer is of utmost importance in numerous biomedical applications, ranging from gene editing to pharmaceutical and vaccine development. In the context of lentiviruses, which are widely used for cell reprogramming in immunotherapies, knowing the e…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Morder, Courtney
  • Licensing Officer: Willson, Christopher

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