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Self-Regulating Platform for Drug-Eluting Medical Meshes
TS-074223 — Researchers at The Ohio State University have developed a self‑regulating manufacturing platform for porous polymer meshes that integrates mesh formation and drug loading in a single step, enabling controlled local delivery from implantable materials.
Technology Overview Implantable meshes and porous polymer films are widely used in surgical, regenerative, and device‑based applications, but current products often separate structural support from drug delivery functions. This platform uses a reaction‑diffusion‑driven process to form poro…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Puskas, Judit; Polyak, Peter
  • Licensing Officer: Panic, Ana

Naked‑Eye Endotoxin Detection via Ligand‑Modified, Lubricant‑Infused Surfaces
TS-073584 — Endotoxins from gram‑negative bacteria pose serious risks in pharmaceutical manufacturing, medical devices, food, and water systems, even at picogram-per-milliliter levels. Current standard methods, such as the LAL assay, require specialized reagents, laboratory infrastructure, and raise cost, s…
  • College: College of Engineering (COE)
  • Inventors: Wang, Xiaoguang "William"; Xu, Yang
  • Licensing Officer: Randhawa, Davinder

Scalable Micro/Nano-Wrinkle Surface Engineering via Corona Discharge
TS-073320 — Current methods for engineering micro- and nanoscale surface topographies on elastomeric materials are often costly, complex, and incompatible with scalable manufacturing. Yet, surface microstructures are critical for enhancing biological interactions in wound healing materials, such as promoting …
  • College: College of Engineering (COE)
  • Inventors: Zhao, Yi
  • Licensing Officer: Randhawa, Davinder

Oxygen-Concentrating Self‑Rescuer (OCSR) for Confined‑Space Emergencies
TS-073264 — Low‑oxygen, toxic environments created by fires or explosions in mines, tunnels, and enclosed spaces remain a leading cause of fatalities for trapped occupants and rescuers. Current self‑contained breathing and escape devices are constrained by limited oxygen supply, bulk, weight, heat generat…
  • College: College of Engineering (COE)
  • Inventors: Seidt, Jeremy; Brune, Ryan; Dutta, Prabir; Klein, Jerome
  • Licensing Officer: Ashouripashaki, Mandana

Method to Determine Tremor Frequency from Deep Brain Stimulation Signals
TS-070304 — The Need Current clinical methods for assessing tremor severity in patients with Parkinson’s disease and other movement disorders rely heavily on subjective, qualitative observations, such as evaluating hand-drawn spirals or observing motor tasks. These approaches lack precision, are difficult…
  • College: College of Engineering (COE)
  • Inventors: Khan, Furrukh; Dalm, Brian; Novikov, David; Thomas, Evan; Zhao, Jessie
  • Licensing Officer: Randhawa, Davinder

Motion-Guided Deep Image Prior (M-DIP) for Dynamic Image Reconstruction in Cardiovascular MRI
TS-069527 — The Need Cardiovascular MRI (CMR) data acquisition is often time-consuming and relies on complex reconstruction methods that do not fully exploit the spatial and temporal structure of CMR data. There is a need for a more efficient, unsupervised approach that can accelerate CMR imaging while maintai…
  • College: College of Engineering (COE)
  • Inventors: Ahmad, Rizwan; Chen, Chong; Sultan, Muhammad
  • Licensing Officer: Randhawa, Davinder

A new modular format for bispecific antibody fragments
TS-068425 — Functionalization of scFvs with cyclic peptide linkers
The Need The high specificity of antibodies has been utilized to develop numerous technologies, tools and therapeutics, like ADCs and radiopharmaceuticals. Engineered antibody fragments like single-chain variable fragments (scFvs) are starting to see their way into the clinic in BiTEs and CAR T. Sc…
  • College: College of Arts & Sciences
  • Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
  • Licensing Officer: Panic, Ana

Noninvasive Rapid Radiation Exposure Assay
TS-068290 — The Need Radiation exposure poses significant health risks, including cancer and other illnesses, making it crucial for clinicians to accurately measure and assess the extent of radiation exposure. Existing methods often require invasive procedures and may not detect exposure at lower dose ranges. …
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Jacob, Naduparambil; Morder, Courtney; Witte, Spencer
  • Licensing Officer: Panic, Ana

Neonatal Blood Vessel Locator for Vascular Access Procedures
TS-067796 — A handheld device for identifying preterm blood vessels in neonatal ICU.
Over 300,000 preterm births in the United States occur annually, representing 10.5% of all live births. Most preterm births occur spontaneously, but some result from medical conditions like infections or pregnancy complications requiring early labor induction or cesarean delivery. Common causes of p…
  • College: College of Engineering (COE)
  • Inventors: Metzler, Sandra; Bresolin, Alejandro; Crawford, Mackenzie; Fernandes, Siddharth; Hardin, Rene; Patel, Aarti; Richards, Hannah; Trainor, Dylan
  • Licensing Officer: Sharick, Joe

Dust Analysis: A Novel Approach to Monitoring Viral Spread
TS-066962 — The Need Viral disease surveillance (e.g. influenza, SARS-CoV-2) in high-risk settings faces several challenges, such as asymptomatic carriers, incomplete reporting, resource limitations, and delayed diagnosis of traditional swab test methods. These challenges could allow a virus to silently spread…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Faith, Seth; Hull, Natalie; Nastasi, Nick; Renninger, Nicole
  • Licensing Officer: Ashouripashaki, Mandana

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