Methods to measure biophysical attributes of the posterior eye

The Need

Glaucoma and myopia are significant causes of vision loss worldwide, affecting millions of people and imposing a substantial socioeconomical burden. Effective vision care strategies are urgently needed to reduce blindness caused by these conditions and mitigate their associated risks. In vivo imaging of the posterior eye, specifically the sclera and optic nerve, is crucial for evaluating a person's risk for glaucoma progression or developing high myopia. However, current imaging methods lack the ability to accurately measure the biophysical attributes of the posterior eye in real-time, presenting a critical need for a more effective and non-invasive imaging technology.

The Technology

Our cutting-edge technology offers an advanced in vivo imaging method to precisely measure the biophysical attributes of the posterior eye, including the sclera and optic nerve. Leveraging optical coherence tomography (OCT) and computational modeling, our method provides detailed insights into the posterior sclera's stiffness, thickness, and radius, allowing for a comprehensive assessment of a person's risk for glaucoma and myopia-related complications. Additionally, our technology captures essential parameters such as optic nerve diameter and spatial distribution of mechanical deformation in response to the ocular pulse, enabling early detection and evaluation of glaucoma risk.

Commercial Applications

  • Ophthalmology Clinics: Our technology can be utilized by ophthalmologists for precise and non-invasive evaluation of a patient's risk for glaucoma progression and myopia-related complications.
  • Vision Care Centers: Vision care centers can incorporate our imaging method as a part of routine eye examinations, enhancing their diagnostic capabilities and enabling personalized treatment plans.
  • Clinical Research: Our technology offers valuable insights for clinical research focused on understanding the mechanisms of glaucoma and myopia, leading to the development of more effective treatment approaches.


  • Early Detection and Prevention: By accurately assessing biophysical attributes of the posterior eye, our technology enables early detection of glaucoma and myopia risk, facilitating timely interventions and prevention of vision loss.
  • Non-Invasive Imaging: Our method is non-invasive, eliminating the need for invasive procedures and reducing patient discomfort during examinations.
  • Personalized Treatment: With detailed information on individual risk factors, our technology empowers healthcare professionals to develop personalized treatment plans tailored to each patient's unique needs.
  • Advancements in Research: Our imaging method opens new avenues for research in the fields of glaucoma and myopia, fostering better understanding and advancements in treatment modalities.

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