TS-073289 — Understanding how cells respond to soluble signals under diffusion-limited conditions remains a significant gap in current in vitro models. Most microfluidic systems rely on convective flow, which does not accurately reflect transport in interstitial tissue or solid tumors, where diffusion dominat…

TS-073264 — Low‑oxygen, toxic environments created by fires or explosions in mines, tunnels, and enclosed spaces remain a leading cause of fatalities for trapped occupants and rescuers. Current self‑contained breathing and escape devices are constrained by limited oxygen supply, bulk, weight, heat generat…

TS-073219 — Global demand for low‑carbon hydrogen is rising, yet current methods carry efficiency penalties, complex gas clean‑up, and cost and footprint burdens. These drawbacks are amplified when upgrading dilute or variable‑quality feedstocks such as biogas and waste‑derived fuels. Industry needs a…

TS-073184 — Direct air capture (DAC) technologies are essential for meeting global carbon‑reduction goals, yet most current systems remain limited by high energy demand, high cost, and materials with insufficient stability. Traditional solid‑sorbent DAC approaches require significant thermal input for reg…

TS-073070 — Manufacturers need a flexible way to improve the quality of local material regions without heavy, fixed tooling or shallow, low‑energy peening. Today’s options often deliver limited depth of improvement, struggle on complex shapes, and can overload robots or require rework. A practical solutio…

TS-073051 — Surgeons routinely hand‑bend standard titanium or stainless‑steel fixation plates to conform to patient anatomy, a manual process that is time‑consuming, inconsistent, and prone to gaps, reversed bends, and unfavorable residual stress. Each of these factors can compromise fixation and outcom…

TS-072941 — Current additive manufacturing (AM) methods for high-performance alloys, such as Inconel 718, face significant challenges: poor control over microstructure, high porosity, and limited resistance to harsh environments (e.g., high temperature, hydrogen attack). These issues lead to premature failure…

TS-072615 — The Need Efficient carbon dioxide (CO₂) utilization and separation remain critical challenges in energy, chemical, and environmental sectors. Existing processes for CO₂ conversion to carbon monoxide (CO) and for separating CO₂/CO mixtures are energy-intensive, costly, and often lack selectivit…

TS-072583 — The Need The ammonia industry is a major contributor to global CO₂ emissions, primarily due to its reliance on fossil fuels for hydrogen production and the energy-intensive air separation process for nitrogen. With over 500 million tons of CO₂ emitted annually from ammonia synthesis, there is a …

TS-072582 — The Need Current hydrogen production methods, such as steam methane reforming, are energy-intensive and emit significant CO₂, posing challenges for industries seeking low-carbon solutions. There is a critical need for scalable, efficient processes that enable continuous hydrogen generation while a…