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Cyclic Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-073895 — The Need In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Cell-penetrating peptides (CPPs) initially were considered a potential solution. Short sequences of amino acid…
  • College: College of Arts & Sciences
  • Inventors: Pei, Dehua
  • Licensing Officer: Dahlman, Jason "Jay"

Scalable Micro/Nano-Wrinkle Surface Engineering via Corona Discharge
TS-073320 — Current methods for engineering micro- and nanoscale surface topographies on elastomeric materials are often costly, complex, and incompatible with scalable manufacturing. Yet, surface microstructures are critical for enhancing biological interactions in wound healing materials, such as promoting …
  • College: College of Engineering (COE)
  • Inventors: Zhao, Yi
  • Licensing Officer: Randhawa, Davinder

Textile Sensors for Neonatal Growth and Safety
TS-073028 — Neonatal units need unobtrusive, continuous monitoring of presence, posture, motion, and growth metrics (recumbent length, optional weight) without cameras, wires, or labor‑intensive workflows. Frequent, accurate measurements are critical for early detection of growth deviations and unsafe sleep…
  • College: College of Engineering (COE)
  • Inventors: Kiourti, Asimina; Militello, Lisa
  • Licensing Officer: Ashouripashaki, Mandana

Strain‑Activated Programmable Surfaces for Controlled Drug Delivery in Mechanically Regulated Diseases
TS-072945 — Many mechanically mediated conditions such as vascular hypertension, glaucoma, and abdominal distension, present intermittent, unpredictable episodes that demand drug release only when symptoms emerge. Conventional platforms often leak at baseline, require external triggers, or cannot synchronize …
  • College: College of Engineering (COE)
  • Inventors: Zhao, Yi
  • Licensing Officer: Randhawa, Davinder

Sustainable Fungal Memristors for Neuromorphic and Eco-Friendly Computing
TS-072329 — The Need The rapid growth of artificial intelligence and neural networks is driving unprecedented demand for energy-efficient, scalable hardware. Conventional memristors require rare earths and complex fabrication, contributing to electronic waste and limiting accessibility. There is a critical need…
  • College: Marion Campus
  • Inventors: LaRocco, John; Hill, Justin; Simonis, John; Tahmina, Qudsia
  • Licensing Officer: Randhawa, Davinder

Flexible Light-Addressable Sensor for High-Resolution Physiological Mapping
TS-072319 — The Need Current methods for mapping electrical potential gradients in biological tissues, such as the brain, rely on high-density electrode arrays fabricated via costly microfabrication techniques. These rigid devices struggle to conform to complex tissue morphologies, limiting their effectiveness …
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Chen, Shulin; Jia, Yizhen; Liu, Tzu Li; Wang, Qi
  • Licensing Officer: Ashouripashaki, Mandana

Wearable Magnetoinductive Smart Textiles for Real-Time Muscle Health Monitoring
TS-072052 — The Need Current wearable sensors for muscle health are limited in their ability to track real-time geometric changes in muscle size and shape, especially outside controlled laboratory environments. Existing solutions, such as force myography and ultrasound, either lack direct geometric insight or a…
  • College: College of Engineering (COE)
  • Inventors: Coogle, Sam; Kiourti, Asimina
  • Licensing Officer: Randhawa, Davinder

Breakthrough In Delivery: Expanding Access to Intracellular Targets for Next-Generation Therapies
TS-072004 — Empower your pipeline with a versatile platform for efficient, customizable biomolecule transport.
Overview Intracellular delivery remains a persistent challenge in drug delivery, gene editing, and biotechnology. Pharmaceutical and biotech companies lose valuable opportunities when promising drugs and biologics cannot reach their intended targets inside cells, limiting product effectiveness and m…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis
  • Licensing Officer: Panic, Ana

Free Energy Spectroscopy: Transforming Molecular Analytics for Next-Generation Biotech and Pharma
TS-071946 — Powering faster, smarter decisions with real-time molecular insights for research and therapeutic development.
Overview Pharmaceutical and biotech companies often face delays and uncertainty in new drug development due to insufficient experimental insight into the shifting behaviors of large biomolecular complexes— processes critical to understanding disease and drug mechanisms. Free Energy Spectrosco…
  • College: College of Arts & Sciences
  • Inventors: Poirier, Michael; Bonin, Kalven; Bundschuh, Ralf; Castro, Carlos
  • Licensing Officer: Panic, Ana

Quantum Defect-Based Ultra-Sensitive Radiation Detection Platform
TS-071847 — The Need Current fast neutron detection technologies suffer from inherently low sensitivity due to the limited interaction cross-section between neutrons and atomic nuclei. This restricts their effectiveness in critical applications such as nuclear security, radiation dosimetry, and advanced imaging…
  • College: College of Engineering (COE)
  • Inventors: Cao, Lei Raymond; Johnston-Halperin, Ezekiel; Shoen, Luke
  • Licensing Officer: Ashouripashaki, Mandana

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