TS-076823 — Solar-blind UV detection (200–280 nm) is essential across defense, fire detection, secure optical communications, environmental monitoring, and space applications. Existing solutions — photomultiplier tubes and filtered silicon photodetectors — are bulky, fragile, require high op…

TS-076401 — Many progressive diseases, including cardiac, neurological, and other chronic disorders, begin with subtle molecular and cellular changes long before conventional clinical signs become detectable. Current diagnostic approaches generally identify disease only after significant tissue remodeling or …

TS-076286 — Literature shows that Negative Pressure Wound Therapy (NPWT) combined with fluid instillation can improve abdominal trauma patient outcomes. Current standards of practice are inefficient, involving assembly and off-label use of at least 8 medical products. This is further complicated by varied pro…

TS-075868 — Clinicians managing pediatric patients supported by a ventricular assist device must routinely assess pump performance by visually estimating membrane fill and ejection during pump cycles. These evaluations are critical for patient management but are inherently subjective, time-consuming, and pron…

TS-075519 — A galactose-based RAFT chain transfer agent (Gal-RAFT) that incorporates a sugar moiety at the polymer terminus, enabling the synthesis of well-defined polymers with an integrated carbohydrate handle for subsequent biological applications.

TS-075262 — PROBLEM Alzheimer’s disease is a progressive brain disorder that destroys memory and thinking, affecting 6–7 million people in the U.S. and over 50 million worldwide. There is currently no cure, and available treatments only temporarily manage symptoms or modestly slow disease progressi…

TS-075261 — Problem Hemolysis, the process by which the red blood cell membrane ruptures, releasing hemoglobin (Hb), is typically managed in mammalian organisms by intrinsic proteins such as hemopexin (Hpx) and haptoglobin (Hp). However, their concentrations in plasma are very limited, so, in conditions with s…

TS-075260 — Problem Type 2 diabetes and related metabolic disorders affect hundreds of millions of patients and are frequently accompanied by chronic inflammation, which accelerates disease progression and complications. Existing antidiabetic therapies often fail to adequately address inflammatory pathways and…

TS-075259 — More than a billion people worldwide suffer from some form of neurological disorder, such as Alzheimer's (AD), Parkinson's (PD), multiple sclerosis, traumatic brain injury, epilepsy, stroke, or spinal injury. These conditions result in more than 7 million deaths, with associated costs exceed…

TS-075258 — PROBLEM Chronic heart failure following myocardial infarction (MI) afflicts ~6.7 million US adults and is driven by maladaptive immune activation, particularly persistent activation and proliferation of CD4+ T cells. Existing anti-inflammatory and immunomodulatory approaches have largely failed to …