Strain‑Activated Programmable Surfaces for Controlled Drug Delivery in Mechanically Regulated Diseases
TS-072945 —
Many mechanically mediated conditions such as vascular hypertension, glaucoma, and abdominal distension, present intermittent, unpredictable episodes that demand drug release only when symptoms emerge. Conventional platforms often leak at baseline, require external triggers, or cannot synchronize …
- College: College of Engineering (COE)
- Inventors: Zhao, Yi
- Licensing Officer: Randhawa, Davinder
Breakthrough In Delivery: Expanding Access to Intracellular Targets for Next-Generation Therapies
TS-072004 — Empower your pipe
line with a versatile platform for efficient, cus
tomizable biomolecule transport.
Overview
Intracellular delivery remains a persistent challenge in drug delivery, gene editing, and biotechnology. Pharmaceutical and biotech companies lose valuable opportunities when promising drugs and biologics cannot reach their intended targets inside cells, limiting product effectiveness and m…
- College: College of Arts & Sciences
- Inventors: Bong, Dennis
- Licensing Officer: Panic, Ana
Quantum Defect-Based Ultra-Sensitive Radiation Detection Platform
TS-071847 — The Need
Current fast neutron detection technologies suffer from inherently low sensitivity due to the limited interaction cross-section between neutrons and atomic nuclei. This restricts their effectiveness in critical applications such as nuclear security, radiation dosimetry, and advanced imaging…
- College: College of Engineering (COE)
- Inventors: Cao, Lei Raymond; Johnston-Halperin, Ezekiel; Shoen, Luke
- Licensing Officer: Ashouripashaki, Mandana
Dust Analysis: A Novel Approach to Monitoring Viral Spread
TS-066962 — The Need
Viral disease surveillance (e.g. influenza, SARS-CoV-2) in high-risk settings faces several challenges, such as asymptomatic carriers, incomplete reporting, resource limitations, and delayed diagnosis of traditional swab test methods. These challenges could allow a virus to silently spread…
- College: College of Engineering (COE)
- Inventors: Dannemiller, Karen; Faith, Seth; Hull, Natalie; Nastasi, Nick; Renninger, Nicole
- Licensing Officer: Ashouripashaki, Mandana
Revolutionizing Corneal Repair: Advanced MG53-Based Treatment for Enhanced Ocular Health
TS-066878 — New and more effective treatments for corneal injuries.
Current treatments for corneal injuries often have side effects that can compromise vision, highlighting the need for a new method that enhances ocular tissue repair without such drawbacks.
The Need
Injuries to the cornea can lead to severe pain, infection, and vision loss due to scarring and abno…
- College: College of Optometry
- Inventors: Chandler, Heather; Ma, Jianjie; Tan, Tao; Zhu, Hua
- Licensing Officer: Schultz, Teri
Small Molecule USP30 Inhibitors for the Treatment and Prevention of Cardiomyopathy
TS-066773 — The Need
Cardiomyopathy, a disease of the heart muscle, poses significant public health challenges due to its diverse causes, symptoms, and potential complications, including heart failure and arrhythmias. With cardiomyopathy often induced by drugs, such as anthracyclines used in chemotherapy, ther…
- College: College of Medicine (COM)
- Inventors: Sun, Nuo; Krigman, Judith; Yang, Mingchong; Zhang, Ruohan
- Licensing Officer: Willson, Christopher
Innovative Small Molecule Inhibitors for Effective Treatment and Prevention of Coronavirus Infections
TS-066750 —
The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has significantly impacted global health and economies. Despite vaccine efforts, issues such as vaccine hesitancy, delays in distribution, and emerging variants have highlighted the need for effective therapeutic interventions. These i…
- College: College of Veterinary Medicine
- Inventors: Sharma, Amit; Li, Pui-Kai "Tom"; Xing, Enming
- Licensing Officer: Willson, Christopher
System for automated high-speed imaging and genetic manipulation of C. elegans on agar media
TS-065892 — The Need
The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …
- College: College of Engineering (COE)
- Inventors: Fang-Yen, Christopher "Chris"; Alhalbi, Serge; Li, Zihao
- Licensing Officer: Randhawa, Davinder
IDEAS: Revolutionizing Early Childhood Education with Automated Interaction Analysis
TS-065825 — The Need: In early childhood education settings, understanding children's interactions, both social and linguistic, is paramount for effective teaching and development monitoring. However, manual observation and analysis of these interactions can be time-consuming and subjective, hindering educa…
- College: College of Education & Human Ecology
- Inventors: Gonzalez Villasanti, Hugo "Hugo"; Justice, Laura
- Licensing Officer: Dahlman, Jason "Jay"
Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year.
The Need
Developing drugs for cance…
- College: College of Arts & Sciences
- Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
- Licensing Officer: Panic, Ana
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