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Breakthrough In Delivery: Expanding Access to Intracellular Targets for Next-Generation Therapies
TS-072004 — Empower your pipeline with a versatile platform for efficient, customizable biomolecule transport.
Overview Intracellular delivery remains a persistent challenge in drug delivery, gene editing, and biotechnology. Pharmaceutical and biotech companies lose valuable opportunities when promising drugs and biologics cannot reach their intended targets inside cells, limiting product effectiveness and m…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis
  • Licensing Officer: Panic, Ana

Free Energy Spectroscopy: Transforming Molecular Analytics for Next-Generation Biotech and Pharma
TS-071946 — Powering faster, smarter decisions with real-time molecular insights for research and therapeutic development.
Overview Pharmaceutical and biotech companies often face delays and uncertainty in new drug development due to insufficient experimental insight into the shifting behaviors of large biomolecular complexes— processes critical to understanding disease and drug mechanisms. Free Energy Spectrosco…
  • College: College of Arts & Sciences
  • Inventors: Poirier, Michael; Bonin, Kalven; Bundschuh, Ralf; Castro, Carlos
  • Licensing Officer: Panic, Ana

Smart Blueberry Extract: The Modern Natural Health Solution for Inflammation Relief and Wellness
TS-071830 — Unlocking plant-powered solutions to deliver effective inflammation relief and enhance disease outcomes.
Overview Chronic inflammation driven by elevated interleukin-11 (IL-11) is a critical underlying cause of tissue scarring and cancer, worsening the disease outcomes over time. Current anti-inflammatory options fall short, offering limited control over IL-11 and failing to stop its persistent buildu…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Giusti, M. Monica; Prasher, Harmeen; Sellers, Patrick; Ziouzenkova, Ouliana
  • Licensing Officer: Panic, Ana

Instant Diagnostics, Anywhere
TS-070543 — A Platform for High-Throughput Biomarker Detection that is portable, fast, and requires minimal sample
The Need The diagnostics market is under increasing pressure to deliver faster, more reliable, and less invasive solutions, driven by growing global health challenges. Current technologies face critical limitations, including large sample requirements, labor-intensive workflows, and reliance on exp…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Seth, Ayesha; Zerrudo, Stephanee
  • Licensing Officer: Panic, Ana

A new modular format for bispecific antibody fragments
TS-068425 — Functionalization of scFvs with cyclic peptide linkers
The Need The high specificity of antibodies has been utilized to develop numerous technologies, tools and therapeutics, like ADCs and radiopharmaceuticals. Engineered antibody fragments like single-chain variable fragments (scFvs) are starting to see their way into the clinic in BiTEs and CAR T. Sc…
  • College: College of Arts & Sciences
  • Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
  • Licensing Officer: Panic, Ana

Noninvasive Rapid Radiation Exposure Assay
TS-068290 — The Need Radiation exposure poses significant health risks, including cancer and other illnesses, making it crucial for clinicians to accurately measure and assess the extent of radiation exposure. Existing methods often require invasive procedures and may not detect exposure at lower dose ranges. …
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Jacob, Naduparambil; Morder, Courtney; Witte, Spencer
  • Licensing Officer: Panic, Ana

RAFT Agents for Controlled Radical Polymerization of Biofunctionalized Polymeric Materials
TS-068081 — These RAFT agents enable synthesis of novel polymer materials with enhanced biocompatibility and tailored functionality, suited for a wide range of biomedical applications.
Background The growing demand for biofunctionalized polymer materials in fields such as drug delivery and diagnostics requires precise control over polymer properties. However, current reagents for Reversible Addition Fragmentation chain Transfer (RAFT) polymerization struggle with achieving the ne…
  • College: College of Arts & Sciences
  • Inventors: Kulkarni, Anuja; Watkins, Davita
  • Licensing Officer: Panic, Ana

Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need: In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
  • Licensing Officer: Panic, Ana

Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
  • Licensing Officer: Panic, Ana

Utilizing WT-IV-012 to improve immune checkpoint therapy in cancer treatment
TS-064262 — The Need Addressing the limitations of current melanoma therapies, there exists a critical need for innovative approaches that enhance the effectiveness of immune checkpoint therapeutics. Despite advancements in immunotherapy, a significant percentage of melanoma patients do not achieve complete re…
  • College: College of Arts & Sciences
  • Inventors: Burd, Craig; Aguilar-Valenzuela, Renan; Burd, Christin
  • Licensing Officer: Panic, Ana

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