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TL-iGeneCombo: Transfer Learning for Individual Sample Specific Gene Combination Effect Prediction and Selection in Cancer Cells
TS-075184 — Problem Synthetic lethality (SL) is defined as a gene combination effect (GCE) of two genes where loss-of-function of both genes, rather than one, causes cell death. While carrying strong therapeutic potential in the treatment of cancer, SL interactions are context specific and sparse, thereby limi…
  • College: College of Medicine (COM)
  • Inventors: Li, Lang; Gökbağ, Birkan
  • Licensing Officer: Hampton, Andrew

EmitGCL: Prediction of Future Metastasis based on Graph Contrastive Learning
TS-075168 — Problem Metastasis is the primary driver of cancer-related deaths, yet accurately predicting its onset is a major clinical challenge. Current diagnostic tools often fail to detect occult metastatic cells and metastatic precursor cells, resulting in either overdiagnosis, with unnecessary treatments,…
  • College: College of Medicine (COM)
  • Inventors: Ma, Qin; Wang, Xiaoying
  • Licensing Officer: Hampton, Andrew

Hybrid Collaborative Filtering Methods for Recommending Search Terms to Clinicians
TS-063237 — Electronic Health Records (EHR) are used in over 88% of all US medical clinics to improve care and streamline data. In addition, they enable sharing of data to multiple providers dealing with the same patient, thereby enhancing efficiency and care. The Need In the last decade, medical practices…
  • College: College of Medicine (COM)
  • Inventors: Ning, Xia; Peng, Bo; Ren, Zhiyun
  • Licensing Officer: Hampton, Andrew

Patient Access Prioritization Score
TS-063212 — When a patient demonstrates signs of imminent clinical deterioration, it is essential to immediately assess and treat the patient to prevent intensive care unit transfer, cardiac arrest, or death. These tasks often include transferring the patient to other facilities with optimal capabilities. T…
  • College: College of Medicine (COM)
  • Inventors: Reinbolt, Raquel; Cohn, David
  • Licensing Officer: Hampton, Andrew

3D Clinical Image-based Pre-surgical planning Tool
TS-053757 — Modernity has brought with it increased complexity in many areas of our lives, an important one being the healthcare industry. Surgical procedures require increased precision while employing intricate methods. With approximately 20 million surgeries performed each year in the United States alone, …
  • College: College of Medicine (COM)
  • Inventors: Powell, Kimerly; Adunka, Oliver; Hittle, Bradley; Keith, Jason; Kerwin, Thomas "Thomas"; Stredney, Donald; Wiet, Gregory
  • Licensing Officer: Randhawa, Davinder

Cochlear Implant Post-Surgical Software
TS-050247 — Software to objectively optimize cochlear implant settings for the post-surgical patient
Each year, over 72,000 severely hearing-impaired patients get a cochlear implant (“CI”) to hear again or to hear for the first time. Specialized audiologists adjust default hearing settings in the patient's implant after the surgery, using a subjective “Which sounds better?&r…
  • College: College of Medicine (COM)
  • Inventors: Skidmore, Jeffrey
  • Licensing Officer: Zinn, Ryan

At-Home Digital Platform for Scoring Skin Disease
TS-038429 — An automated image analysis system for the recognition and quantification of skin disease
Acne and rosacea are skin diseases that affect around 85% of individuals, the former being the most common skin condition afflicting up to 50 million people. There is no gold standard for evaluation of these skin diseases, and their treatment efficacy is generally determined according to a poorly …
  • College: College of Medicine (COM)
  • Inventors: Kaffenberger, Benjamin; Gurcan, Metin
  • Licensing Officer: Hampton, Andrew

Family HealthLink: A Health Risk Assessment Tool
TS-037825 — An online interactive tool that helps a patients and physicians assess a likelihood of cancer or heart disease, based on family history.
Physician documentation of family history in the EPIC® EMR for breast and ovarian cancer has been a common practice for many years, but documentation and assessment for other cancer types (and extended family history) have remained sparse and incomplete (Sweet, Sturm et al. 2015). In addition …
  • College: College of Medicine (COM)
  • Inventors: Sweet, Kevin; Newman, David "David"; Sturm, Amy; Westman, Judith "Judy"
  • Licensing Officer: Taysavang, Panya

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