Available Technologies
# of Displayed Technologies: 6 / 6
Applied Category Filter (Click To Remove): Medical Devices
Retrievable Stentgraft for Vascular Surgery and Regional Drug Delivery
TS-063006 — Medical device for vascular surgery and directed drug delivery
The Need
Injuries involving hemorrhaging from the aorta, particularly in military and trauma settings, pose a significant threat to patients' lives. Current treatment options require clamping which completely restricts blood flow resulting in risks of complications such as coagulopathy and orga…
- College: College of Medicine (COM)
- Inventors: Tillman, Bryan; Kenawy, Dahlia
- Licensing Officer: Schworer, Adam
Revolutionizing Vascular Access Management for Hemodialysis Patients
TS-062693 — Dynamic AVF flow control: A paradigm shift in vascular access management for hemodialysis patients.
Patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) face critical challenges in maintaining functional vascular access. Despite the superiority of arteriovenous fistulas (AVFs) in terms of longevity, infection rates, and cost-effectiveness, over a third of AVFs fail to mature a…
- College: College of Medicine (COM)
- Inventors: Boobes, Khaled
- Licensing Officer: Schultz, Teri
Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
TS-062548 — The Need: Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
Colorectal carcinoma is a significant medical challenge, with a high incidence rate in the USA. Current surgical approaches, along with external imaging technologies, have limitations in accurately detecting cancerous tissues, l…
- College: College of Medicine (COM)
- Inventors: Gong, Li; Tweedle, Michael
- Licensing Officer: Willson, Christopher
Unleashing the Power of Radiotherapy - Enhancing Tumor Oxygenation with Next-Gen Radiosensitizers
TS-062384 — , T2018-092, T2018-354, & T2020-216 This technology provides novel radiosensitizer compounds that are derivatives of papaverine designed to enhance tumor oxygenization without PDE-related side effects.
Papaverine is an FDA-approved phosphodiesterase 10A (PDE10A) inhibitor and its clinical use is due to these effects on blood pressure and vascular tone. However, it was found to also be a potent inhibitor of mitochondrial complex I. Papaverine’s mitochondrial complex I inhibition has been sho…
- College: College of Medicine (COM)
- Inventors: Denko, Nicholas; Benej, Martin; Haines, Ben; Mitton-Fry, Mark
- Licensing Officer: Willson, Christopher
Novel Ergonomic Scalpel Handle
TS-051663 — Alleviate and prevent occupational stresses using this novel scalpel design.
A highly unfortunate outcome of the 2020 coronavirus pandemic is the over 400,000 American deaths that have unexpectedly overloaded medical autopsy services across the United States. With this heightened need for autopsy services previously unseen occupational hazards relating to repetitive motion…
- College: College of Medicine (COM)
- Inventors: Sachire, Jennifer
- Licensing Officer: Schworer, Adam
Perivascular Drug Delivery Nanoplatform for Preventing Restenosis After Open Surgery
TS-039004 — Pericelle: a nanoparticle based perivascular drug delivery system to prevent stenosis and failure in vascular reconstruction surgeries.
Imaging and re-intervention procedures, necessary to maintain open blood vessels following vascular reconstruction surgery, are expensive. For example, the cost of maintenance for an arteriovenous (AV) fistula used in hemodialysis access has been estimated at $15,000/year. In bypass and AV fistula…
- College: College of Medicine (COM)
- Inventors: Kent, K. Craig; Chen, Guojun; Gong, Shaoqin; Guo, Lianwang; Shi, Xudong
- Licensing Officer: Taysavang, Panya
