Available Technologies
# of Displayed Technologies: 4 / 4
Applied Category Filter (Click To Remove): Medical Devices
Skin Healing Technology: Dermal Substitutes and Engineered Skin with Rete Ridges
TS-064046 — Dermal substitute with engineered rete ridges improves epidermal-dermal communication and enhances burn wound treatment.
Massive burn injuries present a critical challenge in wound healing and prevention of infection. Current treatment methods are susceptible to blistering and other problems that can reduce engraftment.
The Need
Cultured epithelial autografts (CEAs) are a vital component in treating large burns, but…
- College: College of Engineering (COE)
- Inventors: Powell, Heather; Bailey, John; Blackstone, Britani "Niki"
- Licensing Officer: Willson, Christopher
Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
TS-062548 — The Need: Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
Colorectal carcinoma is a significant medical challenge, with a high incidence rate in the USA. Current surgical approaches, along with external imaging technologies, have limitations in accurately detecting cancerous tissues, l…
- College: College of Medicine (COM)
- Inventors: Gong, Li; Tweedle, Michael
- Licensing Officer: Willson, Christopher
Unleashing the Power of Radiotherapy - Enhancing Tumor Oxygenation with Next-Gen Radiosensitizers
TS-062384 — , T2018-092, T2018-354, & T2020-216 This technology provides novel radiosensitizer compounds that are derivatives of papaverine designed to enhance tumor oxygenization without PDE-related side effects.
Papaverine is an FDA-approved phosphodiesterase 10A (PDE10A) inhibitor and its clinical use is due to these effects on blood pressure and vascular tone. However, it was found to also be a potent inhibitor of mitochondrial complex I. Papaverine’s mitochondrial complex I inhibition has been sho…
- College: College of Medicine (COM)
- Inventors: Denko, Nicholas; Benej, Martin; Haines, Ben; Mitton-Fry, Mark
- Licensing Officer: Willson, Christopher
DNA-cage erasable labels for fluorescence-based imaging
TS-043819 — Compositions and methods for analyzing multiple biomarkers without damaging tissue.
Histopathology is a cornerstone of tissue analysis used to diagnose many clinical conditions. Many of these diagnoses are based on identifying the presence of specific biomarkers, which can be indicated by colored labels. Currently, only 1-2 markers can be analyzed per slide, reducing accuracy and…
- College: College of Engineering (COE)
- Inventors: Winter, Jessica; Jergens, Elizabeth; Lee, Kil Ho "Kilho"
- Licensing Officer: Willson, Christopher
