# of Displayed Technologies: 3 / 3

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Fluorescent probes for intracellular RNA tracking
TS-062554 — The Need: Intracellular RNA fluorescence labeling is a crucial technique for studying cellular processes and understanding gene expression. However, the conventional MS2 labeling method using protein fusion labels can have drawbacks, such as increased mass, potential steric accessibility issues, and…
  • College: College of Arts & Sciences
  • Inventors: Bong, Dennis; Liang, Yufeng
  • Licensing Officer: Panic, Ana

Revolutionizing Cancer Research: Unveiling the Dynamics of K-Ras for Targeted Therapies
TS-062433 — The Need: Understanding the intricate functions of the K-Ras protein is crucial in combating various types of human cancer. However, the lack of detailed atomic-level information has hindered progress in this area, leaving significant gaps in our comprehension of its roles in health and disease. Th…
  • College: Enterprise for Research, Innovation and Knowledge (ERIK)
  • Inventors: Bruschweiler, Rafael; Bruschweiler-Li, Lei "Lei"; Hansen, Alexandar "Alex"; Xiang, Xinyao; Yuan, Chunhua
  • Licensing Officer: Dahlman, Jason "Jay"

Functionalization of Polymethylmethacrylate (PMMA) Surface by Amination with Polyethyleneimine (PEI) for Applications in Microfluidic Immunoassays, Protein/Enzyme Biochips, and Biocatalysis
TS-037631 — Polymethylmethacrylate (PMMA) is a useful material for development of assays, biochips, and other biological materials. However, PMMA makes for a difficult substrate because of complexities with respect to adhesion. This technology presents two new methods for enhanced protein binding onto PMMA.
Polymethylmethacrylate (PMMA) is a synthetic resin in the acrylic family, often used as a substitute for glass or as a material for biomedical devices. PMMA-based biosensors have low protein binding efficiency and low sensitivity. PMMA is used in a variety of applications like immunoassays, biosen…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling
  • Licensing Officer: Panic, Ana

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