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ElectroTag Diagnostics
TS-074316 — Pre‑Launch Start‑Up Opportunity: Seeking Business Leads ElectroTag is a multiplex diagnostics platform that enables simultaneous measurement of multiple disease‑associated proteins from a small patient sample. The system replaces conventional color‑based labels with mass‑encoded peptide tags that are read by mass spectrometry, delivering higher analytical specificity and a clear path to expanding from small to large biomarker panels while maintaining streamlined workflows.
Technology Overview Clinical and research laboratories are increasingly adopting multi‑marker panels to improve diagnosis, guide therapy selection, and monitor treatment response. Traditional formats such as ELISA plates and lateral flow strips rely on optical or enzymatic signals, which begin to…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Badu-Tawiah, Abraham; Seth, Ayesha; Zerrudo, Stephanee
  • Licensing Officer: Panic, Ana

NucNano: Predictive Drug Screening Platform
TS-071946 — Mechanistic drug screening technology to improve preclinical decision-making and reduce late-stage development risk.
Technology Summary NucNano is an emerging drug screening platform from The Ohio State University designed to help pharmaceutical and biotechnology companies identify more promising therapeutic candidates earlier in development. By moving beyond conventional assays that primarily measure bindin…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Poirier, Michael; Bonin, Kalven; Bundschuh, Ralf; Castro, Carlos
  • Licensing Officer: Panic, Ana

Instant Diagnostics, Anywhere
TS-070543 — A Handheld Diagnostics Platform for Point of Care Rapid Diagnostics
The diagnostics market faces pressure for faster and more reliable solutions that can access even the most remote of locations due to global health challenges. Existing diagnostic technologies require health care providers to choose between cost and diagnostic accuracy. Scalable multiplex biomarke…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Badu-Tawiah, Abraham; Seth, Ayesha; Zerrudo, Stephanee
  • Licensing Officer: Panic, Ana

Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
  • Licensing Officer: Panic, Ana

Fluorescent probes for intracellular RNA tracking
TS-062554 — The Need: Intracellular RNA fluorescence labeling is a crucial technique for studying cellular processes and understanding gene expression. However, the conventional MS2 labeling method using protein fusion labels can have drawbacks, such as increased mass, potential steric accessibility issues, and…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Bong, Dennis; Liang, Yufeng
  • Licensing Officer: Panic, Ana

Paper-based Dried Blood Spheroids for Stabilization of Labile Organic Compounds Stored in Ambient Air
TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.
Dried blood spots on paper substrates offer a facile sample collection, storage, and transportation approach for biofluids. However, variable diffusion, volcanic effects, analyte instability, and difficulty in recovering samples from paper plague this method, lowering confidence in analyte quantif…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Badu-Tawiah, Abraham; Damon, Deidre
  • Licensing Officer: Panic, Ana

Functionalization of Polymethylmethacrylate (PMMA) Surface by Amination with Polyethyleneimine (PEI) for Applications in Microfluidic Immunoassays, Protein/Enzyme Biochips, and Biocatalysis
TS-037631 — Polymethylmethacrylate (PMMA) is a useful material for development of assays, biochips, and other biological materials. However, PMMA makes for a difficult substrate because of complexities with respect to adhesion. This technology presents two new methods for enhanced protein binding onto PMMA.
Polymethylmethacrylate (PMMA) is a synthetic resin in the acrylic family, often used as a substitute for glass or as a material for biomedical devices. PMMA-based biosensors have low protein binding efficiency and low sensitivity. PMMA is used in a variety of applications like immunoassays, biosen…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling
  • Licensing Officer: Panic, Ana

Multichannel Polymer Chips for Rapid Multiplex Enzyme-Linked Immunosorbent Assay
TS-014978 — A more accurate, cost efficient and faster method to one of the most widely used diagnostic tests in the world.
The conventional Enzyme-Linked Immunosorbent Assay, or ELISA, is typically carried out in a 96-well or 384-well microliter plate. The method involves a series of mixing and washing steps, which are not only tedious and laborious, but which also often result in large errors and inconsistent outcome…
  • College: College of Engineering (COE)
  • Inventors: Yang, Shang-Tian "ST"; Bai, Yunling; Huang, Wei-Cho
  • Licensing Officer: Panic, Ana

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