The Need

The diagnostics market faces pressure for faster and more reliable solutions that can access even the most remote of locations due to global health challenges. Existing diagnostic technologies require health care providers to choose between cost and diagnostic accuracy. Scalable multiplex biomarker detection systems that are affordable, efficient, and not tethered to an advanced lab setting are still needed, presenting major commercial opportunities.

The Technology

This diagnostic platform from OSU researchers was engineered to enable reliable patient testing, even in remote and resource-limited regions. By prioritizing low-cost consumables, minimal training requirements, and room temperature sample storage, the system reduces barriers to deployment. Its compact, paper-based design requires only a small sample (<60 µL), is easy to operate, and delivers rapid results (<1hr). High sensitivity is achieved through advanced isobaric peptide probes, ensuring accurate detection even in challenging settings. A compact portable mass spectrometer paired with paper-based sample loading design results in a diagnostics platform that offers portability, scalability, and ease of use, supporting accessible, scalable diagnostics for global healthcare needs.

Commercial Applications

• Clinical Diagnostics
• Point-of-care testing
• Drug discovery and monitoring
• Global health initiatives

Benefits/Advantages

• High sensitivity enables testing of asymptomatic patients.
• Low sample consumption
• Enhanced Multiplexing capabilities
• Portability and accessibility
• Speed and affordability