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Revolutionary NO Sensor for Highly Selective and Sensitive Gas Detection
TS-066249 — A novel sensor leveraging WO3 and Cr2O3 for selective NO detection in harsh environments and breath analysis with high sensitivity at ppb levels.
There is a critical demand for advanced gas sensors capable of selectively detecting nitric oxide (NO) in diverse applications such as environmental monitoring, industrial processes, and medical diagnostics, particularly in challenging environments with interfering gases like carbon monoxide (CO).…
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Govindhan, Maduraiveeran; Mondal, Suvra; Sun, Chenhu
  • Licensing Officer: Zinn, Ryan

Suppressing background carbon incorporation using laser-assisted MOCVD growth of nitride-based semiconductors
TS-063717 — The Need In the world of semiconductor material systems, the demand for advancements in optoelectronic and power electronic devices is ever-growing. The fabrication of semiconductor films, crucial for these applications, primarily relies on epitaxy technologies such as hydride vapor phase epitaxy (…
  • College: College of Engineering (COE)
  • Inventors: Zhao, Hongping; Chen, Zhaoying; Zhang, Yuxuan
  • Licensing Officer: Randhawa, Davinder

Grass Surrogate
TS-062844 — Road departure is a serious threat to vehicle safety and can result in fatal accidents. To prevent road departure, some vehicles are equipped with a road departure mitigation system that can detect when a vehicle is about to leave the road and take corrective actions. However, there is a need for …
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih
  • Licensing Officer: Zinn, Ryan

A Novel MIMO Architecture for Multi-user Power line communication
TS-062843 — This MIMO-PLC architecture is the first scalable MIMO architecture on a single power line. It improves the throughput for power line communication (PLC) by utilizing the existing power delivery infrastructure and allows for high data rates in rural areas.
Home networking and the Internet of Things (IoT), especially voice and video communications, require high throughput, reliable coverage, and sustainable connectivity. However, the performance is dramatically decreased when the wireless signals go through the walls and ceilings. The densely deploye…
  • College: College of Engineering (COE)
  • Inventors: Srinivasan, Kannan; Chen, Bo; Guruvenkata, Vivek; Sun, Wei
  • Licensing Officer: Mess, David

Transducin β-like protein 1 X-Linked Selective Degraders as Anti-cancer Therapeutics
TS-062685 — Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers. The Need Current cancer treatments mainly rely on chemotherapy, radiation, surgery and bon…
  • College: College of Pharmacy
  • Inventors: Cheng, Xiaolin; Alinari, Lapo; Li, Pui-Kai "Tom"; Yang, Rui
  • Licensing Officer: Willson, Christopher

Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
  • Licensing Officer: Dahlman, Jason "Jay"

Scalable laser-assisted MOCVD chamber design with laser array input
TS-050244 — A design of scalable laser-assisted MOCVD chamber for III-nitrides and other semiconductors with a laser array input.
III-nitrides represent an important semiconductor material system for both optoelectronic and power electronic device applications. Advantages for III-nitrides include high electron saturation velocity, high critical electric field, high radiation resistance and decent thermal performance. Therefo…
  • College: College of Engineering (COE)
  • Inventors: Zhao, Hongping; Chen, Zhaoying
  • Licensing Officer: Randhawa, Davinder

An improved base editor (iABE-NG) for correcting genetic diseases such as Duchenne muscular dystrophy
TS-049505 — An engineered base editor (iABE-NG) that uses an SpCas9 variant, a shortened adenine deaminase domain with eliminated RNA off-target activity, and an intein split for packaging into an adeno-associated virus (AAV), resulting in gene mutation correction.
There are thousands of monogenic diseases that are lacking effective therapeutic treatments. The main bottleneck in developing effective treatment is the ability to effectively edit gene while controlling for the myriad of off-target effects that come with targeting the genome. Duchenne Muscular D…
  • College: College of Medicine (COM)
  • Inventors: Han, Renzhi; Gao, Yandi; Xu, Li
  • Licensing Officer: Schworer, Adam

Iron Oxide Composites with Low Concentration of Aliovalent Dopants As Oxygen Carrier Materials for Sustainable Redox Combustion and Gasification Reactions in Chemical Looping Reactor Systems
TS-038513 — Addition of low concentration aliovalent transition metal dopants substantially improves particle performance in chemical loopiong systems
Cyclic systems are required for energy conversion systems. In the clean energy industry, chemical looping offers promise for carbon dioxide capture from fossil energy. Transition metal oxides such as iron oxide, nickel oxide, and copper oxide have been singled out as the desired active oxygen carr…
  • College: College of Engineering (COE)
  • Inventors: Fan, Liang-Shih; Cheng, Zhuo; Chung, Cheng; Guo, Mengqing "MENGQING"; Qin, Lang
  • Licensing Officer: Ashouripashaki, Mandana

Novel Small-Molecule Integrin-linked Kinase/Phosphoinositide-dependent Protein Kinase-2 Inhibitors
TS-037647 — A novel set of molecules that inhibit integrin-linked kinase in order to suppress tumor cell growth and metastasis.
The Akt signaling pathway is responsible for apoptosis, cell proliferation, and metabolism. In tumor cells, this pathway is up-regulated and aids in promoting cancer cell survival. Complete activation of Akt pathway requires phosphorylation at two amino-acid residues, which are phosporylated by se…
  • College: College of Pharmacy
  • Inventors: Chen, Ching-Shih; Kulp, Samuel; Lee, Su-Lin
  • Licensing Officer: Taysavang, Panya

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