Mesoporous Support-Immobilized Metal Oxide Nanoparticles for High-Purity Syngas Generation
TS-071809 — The Need
Syngas is an essential intermediate for producing high-value chemicals such as gasoline, methanol, and dimethyl ether. Current industrial methods (steam reforming, autothermal reforming, and partial oxidation) are energy-intensive, costly, and environmentally burdensome. Moreover, these met…
- College: College of Engineering (COE)
- Inventors: Fan, Liang-Shih; Cheng, Zhuo; Liu, Yan; Qin, Lang
- Licensing Officer: Ashouripashaki, Mandana
Motion-Guided Deep Image Prior (M-DIP) for Dynamic Image Reconstruction in Cardiovascular MRI
TS-069527 — The Need
Cardiovascular MRI (CMR) data acquisition is often time-consuming and relies on complex reconstruction methods that do not fully exploit the spatial and temporal structure of CMR data. There is a need for a more efficient, unsupervised approach that can accelerate CMR imaging while maintai…
- College: College of Engineering (COE)
- Inventors: Ahmad, Rizwan; Chen, Chong; Sultan, Muhammad
- Licensing Officer: Randhawa, Davinder
A Scalable Method for Minimizing Beam-Training Overhead in mmWave Communications
TS-068475 — The Need
As mmWave technology becomes the backbone of 5G and other advanced communication systems, the demand for fast, reliable, and scalable beamforming solutions has surged. Traditional beam-training methods are computationally intensive and time-consuming, leading to delays in establishing high-…
- College: College of Engineering (COE)
- Inventors: Athreya, Kannan; Chen, Wei-Han; Liu, Xin; Parthasarathy, Srinivasan
- Licensing Officer: Randhawa, Davinder
Addressing the Challenges in HCC Treatment with Innovative Technology
TS-062690 — Novel niclosamide analogues with improved bioavailability and mitigated dose-limiting toxicities.
Hepatocellular carcinoma (HCC) poses a significant global health challenge, being a predominant form of liver cancer with high mortality rates. The disease exhibits sexual dimorphism, disproportionately affecting males.
The Need
Despite the crucial role of androgen receptors (AR) in HCC progress…
- College: College of Pharmacy
- Inventors: Coss, Christopher; Cheng, Jeffrey; Cheng, Xiaolin; Kulp, Samuel; Li, Tom; Montgomery, Emma; Xing, Enming
- Licensing Officer: Willson, Christopher
Dual Androgen Receptor/AKR1C3 Inhibitors for Prostate Cancer
TS-062605 — The Need:
Castration-resistant prostate cancer (CRPC) poses a significant challenge in oncology, with existing therapies often leading to resistance and disease progression. Key drivers of resistance include the androgen receptor (AR) and aldo-keto reductase family 1 member C3 (AKR1C3). Novel treat…
- College: College of Pharmacy
- Inventors: Li, Pui-Kai "Tom"; Cheng, Xiaolin; Kong, Xiaotian; Xing, Enming
- Licensing Officer: Schworer, Adam
AI-Enabled Retrosynthesis for Drug Development
TS-060092 — AI methods and systems for predicting reactants and their synthesis paths to support drug design and chemical synthesis.
A time-consuming and costly step in drug development is the identification of drug-like small molecules that display desired properties against a specific biomolecular target and then the synthesis of such molecules if they do not exist. Retrosynthesis is a procedure where such a desired molecule i…
- College: College of Medicine (COM)
- Inventors: Ning, Xia; Chen, Ziqi
- Licensing Officer: Hampton, Andrew