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Revolutionizing Vascular Access Management for Hemodialysis Patients
TS-062693 — Dynamic AVF flow control: A paradigm shift in vascular access management for hemodialysis patients.
Patients with end-stage renal disease (ESRD) undergoing hemodialysis (HD) face critical challenges in maintaining functional vascular access. Despite the superiority of arteriovenous fistulas (AVFs) in terms of longevity, infection rates, and cost-effectiveness, over a third of AVFs fail to mature a…
  • College: College of Medicine (COM)
  • Inventors: Boobes, Khaled
  • Licensing Officer: Schultz, Teri

Nanobody-based Protein Degraders for the Treatment of Neurodegenerative Diseases
TS-062678 — Neurodegenerative diseases including Alzheimer's and Parkinson’s diseases, amyotrophic lateral sclerosis (ALS), prion diseases, and among others affect millions of people in the US. These diseases are relentless, often fatal, and affect fundamental functions – things like moving, bre…
  • College: College of Medicine (COM)
  • Inventors: Chu, Nam; Le, Nhat
  • Licensing Officer: Willson, Christopher

Revolutionizing Cancer Research: Unveiling the Dynamics of K-Ras for Targeted Therapies
TS-062433 — The Need: Understanding the intricate functions of the K-Ras protein is crucial in combating various types of human cancer. However, the lack of detailed atomic-level information has hindered progress in this area, leaving significant gaps in our comprehension of its roles in health and disease. Th…
  • College: Enterprise for Research, Innovation and Knowledge (ERIK)
  • Inventors: Bruschweiler, Rafael; Bruschweiler-Li, Lei "Lei"; Hansen, Alexandar "Alex"; Xiang, Xinyao; Yuan, Chunhua
  • Licensing Officer: Dahlman, Jason "Jay"

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