TS-065892 — The Need The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …

TS-065394 — The Need: In the dairy industry, combating Salmonella Dublin is crucial due to production losses and its impact on human health. Current detection methods, particularly culture-based techniques, are laborious, time-consuming, and lack sensitivity in environmental samples. As a result, treatment effe…

TS-064189 — The Need The current global landscape demands innovative solutions to address the urgent need for a safe and efficacious SARS-CoV-2 vaccine, particularly for the vulnerable population of infants and children under 12 years old. Existing vaccines face challenges in terms of durability, cost, and sta…

TS-062822 — Humanized Antibody-drugs conjugate for chemo-immunotherapy of multiple cancer types

TS-062498 — Novel integrated inductor-based magnetohydrodynamic (MHD) pumps containing liquid metal coolant significantly enhance the thermal management of large-scale, complex electronic systems housed in confined spaces

TS-062494 — A novel magnetohydrodynamic (MHD) pump-based thermal management system design where integration of the cooling apparatus using electronic circuit interconnections achieves improved thermal management at a lower cost.

TS-062421 — The Need: Addressing the Global HTLV-1 Epidemic with a Novel Vaccine Human T cell leukemia virus type-1 (HTLV-1) is a significant global health concern, responsible for causing Adult T cell leukemia/lymphoma (ATLL) and human myelopathy/tropical spastic paraparesis (HAM/TSP). With over 10 million pe…

TS-062318 — The Need Cancer is a significant health problem and a leading cause of death in developed countries. Solid cancers, including prostate, breast, lung, stomach, colon, and pancreatic cancers, pose particularly challenging diagnostic and treatment obstacles. Early detection of these cancers is crucial…

TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public health challenges worldwide. The pressing dema…

TS-062213 — The Need: Preventing Respiratory Syncytial Virus (RSV) Infection and Disease Respiratory Syncytial Virus (RSV) is a highly prevalent and dangerous pathogen responsible for significant morbidity and mortality, particularly in infants, young children, and immunocompromised individuals. Despite its gl…

TS-060181 — The Need Food coloring is an important factor of the consumer's perception of the quality and flavor of a food product, boosting the product's overall success. Not only does it provide a different color to food products, it even helps prevent color loss during long-term storage. However, in…

TS-057725 — The angle at which the gears of a turbine engine are staggered can be manipulated to neutralize harmonic excitations produced by the engine.

TS-054464 — Novel drug delivery system that enables efficient transfer of FDA-approved drugs for the treatment of neurological injuries.

TS-043094 — The Need Establishing healthy eating habits in infants and young children is pivotal for their overall well-being and future dietary choices. However, many parents find it challenging to navigate the intricacies of nutrition, particularly in understanding suitable foods and transitioning between di…

TS-038513 — Addition of low concentration aliovalent transition metal dopants substantially improves particle performance in chemical loopiong systems

TS-037741 — The SMN2 gene contains sequences that regulate the level of inclusion of SMN exon7 in SMN mRNA, and some of these act in a negative manner. Antisense oligonucleotides to block the negative regulating protein binding to these sites can increase inclusion of SMN exon 7 and thus, the amount of SMN being produced.

TS-037689 — Lactose from cheese whey is converted from a dairy byproduct to a useful prebiotic using enzymes immobilized on cotton cloth.

TS-037675 — Novel method of using live attenuated vaccines to prevent infection of hMVP.

TS-037648 — The SMN2 gene contains sequences that regulate the level of inclusion of SMN exon7 in SMN mRNA, and some of these act in a negative manner. Antisense oligonucleotides to block the negative regulating protein binding to these sites can increase inclusion of SMN exon 7 and thus, the amount of SMN being produced.

TS-037590 — A two-stage process that can utilize a number of solid, liquid, or gaseous carbon-based fuels to produce hydrogen gas