Available Technologies
# of Displayed Technologies: 5 / 5
Use of electromagnetic signature to determine the type of integrated circuit
TS-062488 —
Currently, the main method used to detect counterfeit integrated circuits (IC's) is a very simplistic approach based on visual inspection. Unfortunately, many sophisticated counterfeit IC's are indistinguishable from authentic since visually they look almost exactly the same.
Dr. Robert…
- College: College of Engineering (COE)
- Inventors: Lee, Robert; Chapman, Gregg; Nechiyil, Aditya
- Licensing Officer: Zinn, Ryan
Albumin-SN-38 Conjugate (AlbuCure) for Cancer Therapy
TS-057776 —
A novel protein-drug conjugate of human serum albumin chemically conjugated to SN-38, solubilizing the potent chemotherapeutic. This therapy has the potential to treat many tumors with poor prognosis, including pancreatic, lung, breast, colorectal, ovarian, sarcoma, head and neck cancer, urothelial malignancies, and others.
Many solid tumors have poor prognosis despite recent progress in molecularly targeted therapy and immunotherapy. Irinotecan/CPT-11, a chemotherapy on the WHO Essential Medicines List, is approved for use in colorectal cancer, lung cancer, pancreatic cancer, gastric cancer, malignant glioma, and sa…
- College: College of Medicine (COM)
- Inventors: Williams, Terence; Lee, Robert
- Licensing Officer: He, Panqing
A proximity sensor for the detection of hands on a steering wheel
TS-048591 — An embedded coax proximity sensor for the detection of hands or other objects near a vehicle's steering wheel
The coming age of autonomous vehicles will require the development of many new technologies to keep the vehicle occupants safe even when no one is paying attention to the vehicle operation. At present, given the limited capabilities of autonomous vehicles, it is necessary for the driver to monitor…
- College: College of Engineering (COE)
- Inventors: Lee, Robert; Kiourti, Asimina; Wang, Zhenyu
- Licensing Officer: Zinn, Ryan
Nanoparticle Composition for Nucleic Acid Delivery
TS-044109 — Lipid nanoparticles (LNs) usable for the delivery of therapeutic compositions, including, but not limited to nucleic acids (NAs).
Nucleic Acid (NA) based therapies are used to inhibit gene expression. Lipid nanoparticles (LNs) are capable of carrying these therapies into cells. However, this delivery requires overcoming several physiological barriers. For instance, one barrier is the acidic endosome conditions within the cel…
- College: College of Pharmacy
- Inventors: Lee, Robert
- Licensing Officer: He, Panqing
Novel gapmers targeting HOXB-AS3 for Acute Myeloid Leukemia Treatment
TS-037979 — A novel treatment for acute meloid leukemia.
The expression of long non-coding RNAs (lncRNAs) in older adults with cytogenetically normal acute myeloid leukemia (CN-AML) is reported to have prognostic significance. lncRNA HOXB-AS3 was identified among the top up-regulated lncRNAs in NPM1-mutated CN-AML cases. Aberrant expression of HOX genes…
- College: College of Medicine (COM)
- Inventors: Garzon, Ramiro; Dorrance, Adrienne; Kauppinen, M.Sc., Ph.D., Sakari; Lee, Robert; Papaioannou, Dimitrios
- Licensing Officer: He, Panqing
