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Introducing HexaPro VSV: A Breakthrough in COVID-19 Vaccine Technology
TS-064191 — The emergence of SARS-CoV-2 variants poses a significant challenge to existing COVID-19 vaccines, necessitating the development of a more durable and broadly protective solution. Current vaccines show reduced efficacy over time and struggle against Variants of Concern (VoCs) such as Omicron. Addre…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; Chamblee, Michelle; Lu, Mijia; Zhang, Yuexiu
  • Licensing Officer: Dahlman, Jason "Jay"

A next generation intranasal trivalent Measles, Mumps and Covid vaccine
TS-064189 — The Need The current global landscape demands innovative solutions to address the urgent need for a safe and efficacious SARS-CoV-2 vaccine, particularly for the vulnerable population of infants and children under 12 years old. Existing vaccines face challenges in terms of durability, cost, and sta…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; Xu, Jiayu; Zhang, Yuexiu
  • Licensing Officer: Dahlman, Jason "Jay"

A novel VSV-based vaccine platform for Zika virus
TS-062261 — The Need: Addressing the Zika Virus Outbreak The Zika virus outbreak, which started in South America and quickly became a global public health issue, has led to severe neurological disorders, birth defects, and other health complications in affected populations. Despite efforts to combat the virus,…
  • College: College of Medicine (COM)
  • Inventors: Peeples, Mark; Li, Jianrong
  • Licensing Officer: Dahlman, Jason "Jay"

Live Attenuated Mumps Virus-Based SARS-CoV-2 Vaccines for Infants and Children
TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public health challenges worldwide. The pressing dema…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; Boyaka, Prosper; Lu, Mijia; Zhang, Yuexiu
  • Licensing Officer: Dahlman, Jason "Jay"

Novel method for attenuating live vaccine candidates for non-segmented negative-sense RNA viruses
TS-062213 — The Need: Preventing Respiratory Syncytial Virus (RSV) Infection and Disease Respiratory Syncytial Virus (RSV) is a highly prevalent and dangerous pathogen responsible for significant morbidity and mortality, particularly in infants, young children, and immunocompromised individuals. Despite its gl…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; He, Chuan; Lu, Mijia; Niewiesk, Stefan; Peeples, Mark; Xue, Miaoge; Zhang, Zijie; Zhao, Boxuan
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Live Attenuated Vaccines for Pneumoviruses
TS-037753 — A method to create vaccines for pneumoviruses, using recombinant viruses.
The Need Pneumoviruses consist of pathogens that target the upper respiratory tract within their specific hosts. These include many important human and animal pathogens, such as human respiratory syncytial virus (hRSV), hMPV, bovine RSV, pneumonia virus of mice (PVM), and avian metapneumovirus (aMP…
  • College: College of Veterinary Medicine
  • Inventors: Li, Jianrong; Cai, Hui; Peeples, Mark; Wang, Rongzhang
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Live Attenuated Vaccines for Human Metapneumovirus
TS-037675 — Novel method of using live attenuated vaccines to prevent infection of hMVP.
The Need: Human metapneumovirus (hMPV) is a prevalent pathogen causing acute respiratory tract disease in individuals of all ages, especially infants, children, the elderly, and immunocompromised individuals. Despite its global prevalence, there are currently no therapeutics or vaccines available fo…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Li, Jianrong; Wei, Yongwei; Zhang, Yu
  • Licensing Officer: Dahlman, Jason "Jay"

A Novel Vectored Vaccine Against Human Norovirus
TS-037664 — A live recombinant vesicular stomatitis virus (VSV)-vector vaccine composition for human norovirus.
The Need Human norovirus (HuNoV) is a highly contagious and prevalent pathogen responsible for the majority of foodborne gastroenteritis outbreaks worldwide. As HuNoV cannot be grown in cell cultures, developing an effective vaccine against it has proven challenging. Current vaccine studies using v…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Li, Jianrong; Ma, Yuanmei
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Vaccine for Respiratory Syncytial Virus
TS-037299 — Recombinant vesicular stomatitis virus (rVSV) vaccines to fight against respiratory syncytial virus (RSV) infections.
The Need: Respiratory Syncytial Virus (RSV) is a major cause of infant hospitalization due to acute lower respiratory tract infections (ALRI) in children under 5 years of age globally, causing up to 200,000 deaths annually. RSV leads to significantly more hospitalizations than influenza in children …
  • College: College of Veterinary Medicine
  • Inventors: Niewiesk, Stefan; Binjawadagi, Basavaraj; Li, Jianrong; Peeples, Mark
  • Licensing Officer: Dahlman, Jason "Jay"

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