Available Technologies
# of Displayed Technologies: 6 / 6
Targeted Delivery to Cancer Cells using Self-assembled, Camptothecin Nanotubes: Active and Passive Targeting
TS-065860 — The Need: Cancer remains one of the most pressing medical challenges of our time, demanding innovative solutions to enhance treatment efficacy while minimizing systemic toxicity. Conventional chemotherapy agents often suffer from poor solubility, instability, and indiscriminate cytotoxicity, necessi…
- College: College of Arts & Sciences
- Inventors: Parquette, Jonathan; Magliery, Thomas
- Licensing Officer: Dahlman, Jason "Jay"
Mobile Harmful Contaminant Detection System: Home Health Kit for the detection of Allergens, Chemicals and Viruses
TS-052249 — A tool for simply and affordably assessing levels of certain household allergens (including asthma triggers), chemical contaminants (formaldehyde) and viruses (including SARS-CoV-2).
The Need
Household allergens (including Asthma triggers)
Asthma is one of the most common chronic conditions among children in the United States and a major cause of childhood disability. Despite advances in medical treatment, many children have poor asthma control that results in disruptions in s…
- College: College of Engineering (COE)
- Inventors: Dannemiller, Karen; Parquette, Jonathan; Qin, Rongjun
- Licensing Officer: Ashouripashaki, Mandana
Development of a Single Component Methacrylate Adhesive Formulation
TS-042066 — A novel hybrid adhesive that combines the non-toxic, high strength properties of methacrylate adhesives with the bonding characteristics of polyurethanes
Despite the utility of methacrylate adhesive chemistry, applications have been limited to industrial and biomedical use cases. This is due to the curing mechanism, which is initiated by either heat, light or a two-component redox system. This invention describes two strategies to create a single-c…
- College: College of Arts & Sciences
- Inventors: Parquette, Jonathan; Schricker, Scott
- Licensing Officer: Dahlman, Jason "Jay"
Development of Non-Foaming High Strength, Single Component Methacrylate/Polyurethane Adhesive
TS-037956 — A single component, moisture-cured methacrylate/polyurethane hybrid adhesive that combines the non-toxic, high strength properties of methacrylate adhesives with the bonding characteristics of polyurethanes
Methacrylate adhesives are strong and can be used on similar or dissimilar materials, such as plastic, metal, composites, and ceramic. They have excellent peel strength, resist abrasion, and stand up to a fair range of temperatures. They also require little preparation of the surfaces to be bonded…
- College: College of Arts & Sciences
- Inventors: Parquette, Jonathan; Bewick, Nicholas; Schricker, Scott
- Licensing Officer: Dahlman, Jason "Jay"
Novel peptides for the treatment of type 1 and 2 diabetes and their neurological complications
TS-037747 —
A novel peptide therapeutic AAC2 comprising amino acids with a coumarin-modified side chain that improves glucose control and reduces neurological decline and anxiety through activation of the insulin-insensitive glucose transporter 1 (GLUT1).
A national study done in 2016 on US adults with diabetes estimated that 0.5% of the population was diagnosed with type 1 diabetes (T1D) (~1.6 million) and 8.5% was diagnosed with type 2 diabetes (T2D) (~27 million). Globally there are ~415 million adults living with diabetes in 2015, with a projec…
- College: College of Education & Human Ecology
- Inventors: Ziouzenkova, Ouliana; Parquette, Jonathan
- Licensing Officer: He, Panqing
Self-Assembly of Therapeutic-Agent Nanostructures
TS-014812 — An improved delivery mechanism has been developed for hydrophobic drugs such as camptothecin which will increase chemotherapeutic efficacy.
Many cancer therapeutics exhibit extremely toxic side effects or have limited efficacy due to low bio-availability. Existing drug delivery technologies can add excessive mass to the therapeutic, grossly expanding the dosage necessary for response. Camptothecin (CPT) is a naturally occurring compou…
- College: College of Arts & Sciences
- Inventors: Parquette, Jonathan; Grinstaff, Mark; Kaplan, Jonah; Kim, Se Hye
- Licensing Officer: Dahlman, Jason "Jay"
