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MicroRNA profile predicts colon cancer prognosis
TS-065453 — The Need: Colon cancer remains one of the most prevalent and lethal forms of cancer worldwide. Timely and accurate diagnosis is critical for effective treatment and improved patient outcomes. Current diagnostic methods often lack the precision and sensitivity needed for early detection and prognosi…
  • College: College of Medicine (COM)
  • Inventors: Croce, Carlo
  • Licensing Officer: Schultz, Teri

Rapid Viral Quantification with Target Gene Detection
TS-062346 — The Need The ability to rapidly identify and determine virus titer is of utmost importance in numerous biomedical applications, ranging from gene editing to pharmaceutical and vaccine development. Current methods for characterizing viruses and determining viral titer, such as ELISA, PCR, and cell c…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Morder, Courtney
  • Licensing Officer: Dahlman, Jason "Jay"

DAT-CI knock-in mouse model carrying a modified dopamine transporter that maintains the transport function but resistant to cocaine inhibition and thus showing no rewarding cocaine effects
TS-058669 — A knock-in mouse model carrying a modified dopamine transporter that is resistant to cocaine inhibition and thus showing no rewarding cocaine effects.
Cocaine abuse has been an issue in the United States since the late 1980s. The highly addictive qualities along with the low cost ruined people’s lives and destroyed communities. Naloxone (marketed as Narcan) is highly effective but can only be used in the event of an overdose. Therefore, th…
  • College: College of Medicine (COM)
  • Inventors: Gu, Howard
  • Licensing Officer: Schultz, Teri

NET-CI knock-in mouse model with a modified norepinephrine transporter carrying triple mutations that maintains the transport function and makes the transporter protein resistant to cocaine and antidepressants
TS-058668 — A knock-in mouse model with a modified norepinephrine transporter carrying triple mutations that makes the transporter protein resistant to cocaine and antidepressants.
Cocaine abuse has been an issue in the United States since the late 1980s. Furthermore, antidepressants also quite dangerous, with nearly 14% of users (who have bipolar disorder) experiencing dependence. Naloxone (marketed as Narcan) is highly effective but can only be used in the event of an over…
  • College: College of Medicine (COM)
  • Inventors: Gu, Howard
  • Licensing Officer: Schultz, Teri

The Buckeye Quit Stick: A novel support device to address the hand-to-oral cigarette habit of patients who are attempting to quit smoking
TS-050189 — A novel support device to address the hand-to-oral cigarette habits of patients who are attempting to quit smoking.
The Need Tobacco addiction is a common problem in cancer patients and more than half of newly diagnosed lung cancer patients are active smokers. Smoking can affect a patient’s surgical safety, quality of life, and cancer recovery and survival outcomes. While treatment products can successfull…
  • College: College of Nursing
  • Inventors: Both, Deborah; Eastep, Christine
  • Licensing Officer: Schultz, Teri

Topical Compounds to Treat Leishmania
TS-014819 — A new class of drugs for the treatment of Leishmania.
Leishmaniasis is an infection caused by Leishmania parasites, spread by the bite of phlebotomine sand flies. It is prevalent in the tropics, subtropics, and southern Europe and is considered a neglected disease. Over a million people are infected with the parasite yearly, leading to skin sores and i…
  • College: College of Medicine (COM)
  • Inventors: Satoskar, Abhay; Fuchs, James; Isaac-Marquez, Angelica; Kinghorn, Alan "Dr. A. Douglas Kinghorn"; Lezama-Davila, Claudio; Pan, Li
  • Licensing Officer: Schultz, Teri

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