Unveiling Unreported Pain: A Systematic Approach for Enhanced Patient Care
TS-064835 — The Need
In healthcare, accurately assessing and managing pain is paramount for patient well-being and treatment efficacy. However, conventional methods of pain assessment rely heavily on verbal communication from patients, which poses challenges for individuals unable to express their pain verball…
- College: College of Nursing
- Inventors: Monroe, Todd
- Licensing Officer: Taysavang, Panya
E-Cadherin-based Oncolytic Viral Cancer for Glioblastoma
TS-062682 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately 40% living the first-year post-diagnosis and 17% in the second year.
The Need
Oncolytic viruses (OVs) are a prom…
- College: College of Medicine (COM)
- Inventors: Yu, Jianhua; Caligiuri, Michael; Xu, Bo
- Licensing Officer: Taysavang, Panya
Selective Estrogen Receptor Beta Agonists
TS-062681 — According to the American Cancer Society, breast cancer is the most common cancer for women in the US, except for skin cancer. It comprised about 30% of all new female cancers each year. While breast cancer death rates have decreased over the last several decades, it remains the second leading cause…
- College: OSU Wexner Medical Center
- Inventors: Bennett, Chad; Wang, Dasheng
- Licensing Officer: Taysavang, Panya
Selective Estrogen Receptor Beta Agonists
TS-062680 — According to the American Cancer Society, breast cancer is the most common cancer for women in the US, except for skin cancer. It comprised about 30% of all new female cancers each year. While breast cancer death rates have decreased over the last several decades, it remains the second leading cause…
- College: College of Pharmacy
- Inventors: Bennett, Chad; Wang, Dasheng
- Licensing Officer: Taysavang, Panya
Bi-specific T-Cell Engagers as Anti-cancer Therapeutics
TS-062677 — Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers.
The Need
Current cancer treatments mainly rely on chemotherapy, radiation, surgery and bon…
- College: College of Medicine (COM)
- Inventors: Caligiuri, Michael; Chan, Wing; Yu, Jianhua
- Licensing Officer: Taysavang, Panya
Nras Mouse Melanoma Cell Lines
TS-049491 — Dr. Christin Burd's lab at The Ohio State University has developed a set of Nras-mutant mouse melanoma cell lines that can be used for preclinical tumor immunology and cancer biology studies.
Studies show that 15-30% of melanomas are Nras driven and 60% of melanomas are Braf driven. Dr. Christin Burd's lab at The Ohio State University has developed a set of Nras-mutant mouse melanoma cell lines that complement a set of Braf cell lines developed by Marcus Bosenberg at Yale Universit…
- College: College of Medicine (COM)
- Inventors: Burd, Christin; Murphy, Brandon
- Licensing Officer: Taysavang, Panya
Junctional Tourniquet for Groin and Axillary Regions
TS-041808 — A tourniquet with a ratcheting lock to keep pressure on wounds in the groin and axillary regions. Hemostasis can be achieved while the patient is still in the field.
Patients with blood loss in the field need to be treated immediately to prevent ongoing blood loss, shock, and death; bleeding from extremity and junctional wounds is the leading cause of potentially preventable death from penetrating injuries. Direct manual pressure is effective for the initial c…
- College: OSU Wexner Medical Center
- Inventors: Nocera, Tanya; Graham, Nadi; McElroy, James
- Licensing Officer: Taysavang, Panya
Mobile Application to Reduce the Risk of Narcotics Abuse Through Patient and Provider Empowerment
TS-041604 — This mobile application for pain management provides simple tools for patients, providers and researchers to use during clinical trials. The app not only tracks the efficacy of each patient's treatment, it can provide additional information to supplement and support the needs of the clinical trial.
The recent opioid epidemic has devastated American cities and kills 91 Americans per day. 80% of these addicts start with prescription pain killers. Preventative strategies to lower opioid use must be developed as most state adopted regulatory measures have failed. The development of such preventa…
- College: College of Medicine (COM)
- Inventors: Chandawarkar, Rajiv; Capek, Allison
- Licensing Officer: Taysavang, Panya
A Small Molecule That Disperses Salmonella Biofilms
TS-041469 — A new compound to eliminate Salmonella biofilms to reduce typhoid fever.
The bacterium Salmonella enterica serovar Typhi (S. Typhi) is the causative agent of typhoid fever – infecting and killing an estimated 21 million and 200,000 individuals each year, respectively. Individuals contract the disease by consuming food or water contaminated with the etiologic agent …
- College: College of Medicine (COM)
- Inventors: Gunn, John; Huggins, William; Kuo, Laura; Melander, Christian
- Licensing Officer: Taysavang, Panya
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