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A modified intein for temperature sensitive applications
TS-063697 — Controlled Protein Release Over a Broad Range of Temperatures
The Need: In the biotechnology field, the demand for efficient protein purification methods and innovative drug delivery solutions is ever-growing. Researchers and companies require technologies that can streamline the purification process, ensuring high yields and purity, while offering versatile …
  • College: College of Engineering (COE)
  • Inventors: Wood, David; Coolbaugh, Michael; Stimple, Samuel "Sam"; Yuan, Hongyu
  • Licensing Officer: Dahlman, Jason "Jay"

Process Monitoring of Internal Temperature Distribution of Powder Bed Fusion Parts
TS-047605 — An ensemble kamlan filter (EnKF) state observer algorithm and process monitoring method for more quickly and accurately estimating the internal temperature gradient of Powder Bed Fusion parts for enhanced process monitoring and control.
Powder Bed Fusion (PBF) is a subset of additive manufacturing processes that performs a layer-by-layer fabrication of metal components by selectively melting metal powder disbursed over the earlier layer. PBF processes encompass methods such as selective laser sintering (SLS), direct metal laser s…
  • College: College of Engineering (COE)
  • Inventors: Wood, Nathaniel; Hoelzle, David
  • Licensing Officer: Zinn, Ryan

Fingerloop sRNA Nanotechnology for Metabolic Engineering and Synthetic Biology
TS-037383 — Functional "fingerloop" RNA antisense motifs for metabolic engineering and RNA nanotechnology applications.
The Need Synthetic biology holds tremendous promise to revolutionize how numerous products are made. For example, microorganisms can be harnessed to produce useful products such as biofuels, chemicals, therapeutics, fragrances, and antibodies, just to name a few examples. However, metabolic enginee…
  • College: College of Engineering (COE)
  • Inventors: Lease, Richard; Lahiry, Ashwin; Stimple, Samuel "Sam"; Wood, David
  • Licensing Officer: Dahlman, Jason "Jay"

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