Composition and Methods for Breast Cancer Diagnosis and Treatment

The Need:

Breast cancer continues to be a significant health challenge, affecting a large number of women worldwide and remaining the second leading cause of cancer-related deaths among women in the United States. Despite advancements in detection and treatment, there is no universally successful method for managing breast cancer, and improvements are needed to enhance diagnosis, treatment, and prevention of the disease. There is a critical need for a precise and effective solution that can aid in early diagnosis, prognosis, and targeted treatment strategies to combat breast cancer and improve patient outcomes.

The Technology:

Our groundbreaking technology is based on the discovery and study of microRNAs (miRNAs), a class of small non-coding RNAs that play vital roles in gene expression regulation. We have identified a breast cancer-specific signature of miRNAs that exhibit differential expression in breast cancer cells compared to normal cells. This signature enables us to diagnose breast cancer accurately, assess prognosis based on prognostic markers, and develop personalized treatment strategies.

Commercial Applications:

  1. Accurate Breast Cancer Diagnosis: Our technology allows for precise and early diagnosis of breast cancer by measuring the level of specific miRNA gene products in a test sample and comparing them with control samples.

  2. Prognostic Marker Identification: We can identify specific miRNAs associated with adverse prognostic markers in breast cancer, providing valuable insights into the disease's severity and progression.

  3. Personalized Treatment Strategies: By analyzing miRNA expression levels in breast cancer cells, we can tailor treatment plans to inhibit the proliferation of cancer cells effectively.

  4. Drug Development: Our technology opens new avenues for identifying potential anti-breast cancer agents, enabling pharmaceutical companies to develop targeted therapies.

  5. Research and Biomarker Discovery: Researchers can utilize our miRNA microarray technology to discover novel biomarkers and explore miRNA-mediated gene regulatory mechanisms in breast cancer and other diseases.


  1. Early Detection and Prognosis: Our technology facilitates early detection of breast cancer and provides valuable prognostic information, enabling timely interventions and improved patient outcomes.

  2. Precision Medicine: By identifying specific miRNA signatures, we enable personalized treatment plans, ensuring that patients receive targeted therapies tailored to their unique genetic profiles.

  3. Reduced Treatment Side Effects: Targeted therapies based on miRNA analysis may result in more effective treatments with fewer adverse side effects, enhancing patients' quality of life during breast cancer treatment.

  4. Enhanced Drug Development: Our technology expedites the identification of potential anti-breast cancer agents, accelerating drug development efforts and improving treatment options for patients.

  5. Advancement in Research: Researchers can leverage our miRNA microarray technology to deepen their understanding of miRNA-mediated gene regulation in breast cancer and pave the way for further advancements in breast cancer research.

Our technology represents a game-changing approach to breast cancer diagnosis and treatment, with the potential to revolutionize the way we combat this devastating disease. Join us in our mission to improve the lives of women affected by breast cancer and shape the future of breast cancer management.


Patent # Title Country
8658370 MicroRNA-Based Methods and Compositions for the Diagnosis and Treatment of Breast Cancer United States of America

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