The Need

In today's fast-paced and demanding world, the need for innovative solutions that enhance mental well-being and cognitive performance has never been greater. Recent scientific discoveries have highlighted the crucial role of the gut-brain connection in influencing human behavior and brain function. It is evident that the metabolites produced by the gut microbiota, including neurotransmitters such as glutamate, GABA, serotonin, and dopamine, play a vital role in regulating brain health and function. Leveraging this knowledge opens up new possibilities for addressing mental health challenges and improving overall cognitive capabilities.

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The Technology

Our cutting-edge technology harnesses the power of the gut-brain axis by enhancing microbial neurotransmitter production. Through extensive research, OSU researchers have identified specific lactic acid bacteria that show enhanced neurotransmitter production when in the presence of milk fat globule membrane (MFGM). By leveraging this naturally occurring microbial phenomenon, we enable the gut microbiota to synthesize neurotransmitters like glutamate, GABA, serotonin, and dopamine within the digestive system.

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Commercial Applications

• Functional Foods and Beverages: By incorporating this technology into functional foods, especially dairy-based products, emotional and cognitive health could be further supported.
• Dietary Supplements: Formulation of novel dietary supplements targeting mental health, stress management, sleep improvement, and cognitive enhancement.

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Benefits/Advantages

• Enhanced Bioavailability: Unlike traditional supplements that face challenges penetrating the blood-brain barrier, our technology directly influences neurotransmitter levels in the gut, leading to enhanced bioavailability and more efficient results.
• Stress and Mood Regulation: By enhancing neurotransmitter production in the gut, our approach could help alleviate conditions like anxiety, depression, and cognitive decline.
• Supports Cognitive Function: With the ability to influence neurotransmitter levels, our technology opens avenues for developing products that support improved focus, memory, and overall cognitive performance.
• Additional Health Benefits: In addition to enhanced gut neurotransmitter, this technology may confer additional benefits as MFGM and Lactic Acid Bacteria are known to provide health benefits on their own, such as supporting gut health and function as well as better immune responses.