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Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-066751 — In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Traditional methods face challenges with membrane impermeability and degradation of therapeutic compounds, limiting th…
  • College: College of Arts & Sciences
  • Inventors: Pei, Dehua
  • Licensing Officer: Dahlman, Jason "Jay"

Genetically Encodable Cyclic Cell-Penetrating Peptides and Uses Thereof
TS-062617 — The Need: In today's fast-paced world, effective drug delivery remains a paramount challenge in achieving therapeutic outcomes. Pharmaceutical industries and researchers are in pursuit of innovative technologies to overcome cellular barriers and deliver therapeutic agents precisely. Addressing t…
  • College: College of Arts & Sciences
  • Inventors: Pei, Dehua
  • Licensing Officer: Dahlman, Jason "Jay"

Novel use of novobiocin to potentiate the antimicrobial efficacy of polymyxins
TS-062439 — The Need: Addressing the Growing Threat of Gram-Negative Bacterial Infections Gram-negative bacterial pathogens, including Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae, are responsible for more than 35% of common hospital-acquired infections. These no…
  • College: College of Arts & Sciences
  • Inventors: Kahne, Daniel; Baidin, Vadim; Mandler, Michael; Ruiz, Natividad
  • Licensing Officer: Dahlman, Jason "Jay"

An Improved Meal Replacement Product for Post- Bariatric Surgery
TS-062425 — The Need: In the world of healthcare, there is a critical need for a nutritional supplement that can effectively strengthen and promote general health, especially for individuals with limited food intake and compromised ability to absorb nutrients. Patients undergoing bariatric surgery, chemothera…
  • College: College of Education & Human Ecology
  • Inventors: DiSilvestro, Robert
  • Licensing Officer: Dahlman, Jason "Jay"

Medical Food for Cystic Fibrosis
TS-062420 — The Need: Addressing Nutritional Challenges in Cystic Fibrosis Cystic Fibrosis (CF) presents significant nutritional challenges for individuals living with the condition. Due to the increased energy requirements and difficulties in nutrient absorption, CF patients often struggle to maintain adequat…
  • College: College of Education & Human Ecology
  • Inventors: DiSilvestro, Robert
  • Licensing Officer: Dahlman, Jason "Jay"

Mini-PCDH15 for treatment of deafness
TS-050433 — A gene therapy solution for Usher Syndrome Type 1F.
Mutations in PCDH15 cause Usher 1F, a recessive syndrome characterized by profound congenital deafness and absence of vestibular function, and progressive blindness beginning in the second decade. Because patients who lack hearing and balance rely on vision for communication and mobility, the late…
  • College: College of Arts & Sciences
  • Inventors: Sotomayor, Marcos
  • Licensing Officer: Dahlman, Jason "Jay"

Novel Live Attenuated Vaccines for Human Metapneumovirus
TS-037675 — Novel method of using live attenuated vaccines to prevent infection of hMVP.
The Need: Human metapneumovirus (hMPV) is a prevalent pathogen causing acute respiratory tract disease in individuals of all ages, especially infants, children, the elderly, and immunocompromised individuals. Despite its global prevalence, there are currently no therapeutics or vaccines available fo…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Li, Jianrong; Wei, Yongwei; Zhang, Yu
  • Licensing Officer: Dahlman, Jason "Jay"

A Novel Vectored Vaccine Against Human Norovirus
TS-037664 — A live recombinant vesicular stomatitis virus (VSV)-vector vaccine composition for human norovirus.
The Need Human norovirus (HuNoV) is a highly contagious and prevalent pathogen responsible for the majority of foodborne gastroenteritis outbreaks worldwide. As HuNoV cannot be grown in cell cultures, developing an effective vaccine against it has proven challenging. Current vaccine studies using v…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Li, Jianrong; Ma, Yuanmei
  • Licensing Officer: Dahlman, Jason "Jay"

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