Advanced Dual-Layer Compositions for Enhanced Delivery and Stability of Biologically Active Agents
TS-066770 — The Need
In the realm of human and mammalian health, delivering biologically active components that are sensitive to moisture or other environmental factors has posed a significant challenge. Traditional methods, such as encapsulation or use of desiccants, often fall short in ensuring stability and…
- College: Office of Business and Finance
- Inventors:
- Licensing Officer: Dahlman, Jason
"Jay"
Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-066751 —
In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Traditional methods face challenges with membrane impermeability and degradation of therapeutic compounds, limiting th…
- College: College of Arts & Sciences
- Inventors: Pei, Dehua
- Licensing Officer: Dahlman, Jason
"Jay"
Intracellular Targeting by Monoclonal Antibodies
TS-064581 — Antibodies are essential therapeutic modalities for treating a plethora of different diseases, ranging from cancer, autoimmune disorders, degenerative diseases, and inflammation. The FDA approved the first antibody over three decades ago, and since more than 570 have been studied in clinical trials,…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
- Licensing Officer: Dahlman, Jason
"Jay"
Small molecules that suppress heat/pain perception
TS-064187 — The Need
In the culinary and pharmaceutical realms, the need for a groundbreaking solution to modulate flavor and alleviate sensory perceptions is crucial. Businesses seek innovative ways to enhance consumer experiences by addressing pungency in foods and alleviating burn or pain sensations in phar…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Peterson, Devin; Borcherding, Joel
- Licensing Officer: Dahlman, Jason
"Jay"
Underwater Zooplankton Enhancing Light Array (UZELA); A Novel Device for Stimulating Nutritional Therapy in Corals
TS-062571 —
The Need
Coral reefs are declining at an alarming rate. When temperatures increase by as little as 1-2 °C above their normal thermal maximum for as little as ten days, corals become stressed, lose their endosymbiotic algae, and turn white – hence the term bleaching. When bleached, corals…
- College: College of Arts & Sciences
- Inventors: Grottoli, Andrea; Dixon, Shannon; Hulver, Ann Marie; Jackson, Eric; Shea, Ryan; Steck, James
- Licensing Officer: Dahlman, Jason
"Jay"
Addressing the Challenges in Cancer Imaging
TS-062545 — The Need: Addressing the Challenges in Cancer Imaging
Cancer continues to be a major cause of global mortality, with over 10% of all deaths attributed to this devastating disease. Despite significant advancements in cancer research, there remains a critical need to enhance current techniques for pr…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Long, Nicholas; Sullivan, Brandon
- Licensing Officer: Dahlman, Jason
"Jay"
Addressing the Challenges in Cancer Imaging
TS-062544 — The Need: Addressing the Challenges in Cancer Imaging
Cancer continues to be a major cause of global mortality, with over 10% of all deaths attributed to this devastating disease. Despite significant advancements in cancer research, there remains a critical need to enhance current techniques for pr…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Allen, Heather; Alten, Edward; Hitchcock, Charles; Long, Nicholas; Martin, Edward; Sullivan, Brandon
- Licensing Officer: Dahlman, Jason
"Jay"
Novel use of novobiocin to potentiate the antimicrobial efficacy of polymyxins
TS-062439 — The Need: Addressing the Growing Threat of Gram-Negative Bacterial Infections
Gram-negative bacterial pathogens, including Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa, and Klebsiella pneumoniae, are responsible for more than 35% of common hospital-acquired infections. These no…
- College: College of Arts & Sciences
- Inventors: Kahne, Daniel; Baidin, Vadim; Mandler, Michael; Ruiz, Natividad
- Licensing Officer: Dahlman, Jason
"Jay"
Medical Food for Cystic Fibrosis
TS-062420 — The Need: Addressing Nutritional Challenges in Cystic Fibrosis
Cystic Fibrosis (CF) presents significant nutritional challenges for individuals living with the condition. Due to the increased energy requirements and difficulties in nutrient absorption, CF patients often struggle to maintain adequat…
- College: College of Education & Human Ecology
- Inventors: DiSilvestro, Robert
- Licensing Officer: Dahlman, Jason
"Jay"
Mini-PCDH15 for treatment of deafness
TS-050433 — A gene therapy solution for Usher Syndrome Type 1F.
Mutations in PCDH15 cause Usher 1F, a recessive syndrome characterized by profound congenital deafness and absence of vestibular function, and progressive blindness beginning in the second decade. Because patients who lack hearing and balance rely on vision for communication and mobility, the late…
- College: College of Arts & Sciences
- Inventors: Sotomayor, Marcos
- Licensing Officer: Dahlman, Jason
"Jay"
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