Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
TS-062548 — The Need: Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
Colorectal carcinoma is a significant medical challenge, with a high incidence rate in the USA. Current surgical approaches, along with external imaging technologies, have limitations in accurately detecting cancerous tissues, l…
- College: College of Medicine (COM)
- Inventors: Gong, Li; Tweedle, Michael
- Licensing Officer: Willson, Christopher
MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Solid Cancers
TS-062318 — The Need
Cancer is a significant health problem and a leading cause of death in developed countries. Solid cancers, including prostate, breast, lung, stomach, colon, and pancreatic cancers, pose particularly challenging diagnostic and treatment obstacles. Early detection of these cancers is crucial…
- College: College of Medicine (COM)
- Inventors: Croce, Carlo; Calin, George; Volinia, Stefano
- Licensing Officer: Willson, Christopher
Diagnostics and Prognostics of Prostate Cancer
TS-062299 — The Need: Addressing Prostate Cancer Diagnostics and Therapeutics
Prostate cancer remains a significant challenge in medical diagnosis and treatment, requiring advancements in diagnostics, therapeutics, and prognostics. Current approaches fall short in providing accurate and effective solutions, le…
- College: College of Medicine (COM)
- Inventors: Croce, Carlo
- Licensing Officer: Willson, Christopher
MicroRNA signatures in human ovarian cancer
TS-062298 — The Need:
Ovarian cancer remains a significant challenge in the field of medicine, with late-stage diagnosis and limited effective treatments contributing to high mortality rates. The need for improved diagnostic tools and targeted therapies is evident to address this aggressive disease. Convention…
- College: College of Medicine (COM)
- Inventors: Croce, Carlo
- Licensing Officer: Willson, Christopher
Composition and Methods for Lung Cancer Diagnosis and Treatment
TS-062296 — The Need: Advancing Lung Cancer Detection and Treatment
Lung cancer continues to be a global health concern, accounting for the highest number of cancer-related deaths worldwide. In the United States, it is the leading cause of cancer mortality for both men and women, with a disheartening five-year…
- College: College of Medicine (COM)
- Inventors: Croce, Carlo; Calin, George
- Licensing Officer: Willson, Christopher
Composition and Methods for Breast Cancer Diagnosis and Treatment
TS-062295 — The Need:
Breast cancer continues to be a significant health challenge, affecting a large number of women worldwide and remaining the second leading cause of cancer-related deaths among women in the United States. Despite advancements in detection and treatment, there is no universally successful m…
- College: College of Medicine (COM)
- Inventors: Croce, Carlo; Calin, George
- Licensing Officer: Willson, Christopher
DNA-cage erasable labels for fluorescence-based imaging
TS-043819 — Compositions and methods for analyzing multiple biomarkers without damaging tissue.
Histopathology is a cornerstone of tissue analysis used to diagnose many clinical conditions. Many of these diagnoses are based on identifying the presence of specific biomarkers, which can be indicated by colored labels. Currently, only 1-2 markers can be analyzed per slide, reducing accuracy and…
- College: College of Engineering (COE)
- Inventors: Winter, Jessica; Jergens, Elizabeth; Lee, Kil Ho "Kilho"
- Licensing Officer: Willson, Christopher
Circulating Microvesicles Biomarkers and Molecular Targets in Disease
TS-035400 — Discovery of microvesicles containing microRNA from myeloid cells that can serve as biomarkers and molecular targets
The Need: The advancement of microRNA (miRNA) research has uncovered their crucial role in regulating gene expression, cell function, and differentiation. These small non-coding RNAs are present in animals and plants and have been associated with various diseases, including cancer and inflammatory d…
- College: College of Medicine (COM)
- Inventors: Marsh, Clay; Ismail, Noura; Piper, Melissa
- Licensing Officer: Willson, Christopher
Rapid Diagnosis of a Disease Condition using Infrared Spectroscopy
TS-014897 — This invention aids rapid diagnosis of a disease condition through the use of infrared spectral data and multivariate disease classification models.
The Need: Functional syndromes, such as chronic fatigue syndrome, fibromyalgia, interstitial cystitis (IC), and irritable bowel syndrome, pose significant challenges for healthcare providers due to their elusive pathophysiological mechanisms and overlapping symptoms with other conditions. The lack o…
- College: College of Veterinary Medicine
- Inventors: Buffington, Charles "Tony"; Rodriguez-Saona, Luis; Rubio Diaz, Daniel; Stella, Judith
- Licensing Officer: Willson, Christopher