Available Technologies
# of Displayed Technologies: 4 / 4
Applied Category Filter (Click To Remove): Small Molecules
Precision RNA-PROTACs: Revolutionizing Therapeutic Targeting of Dysregulated Ribonucleoprotein Complexes
TS-065457 — The Need:
In the realm of therapeutic development, there's a pressing need for precise targeting of dysregulated ribonucleoprotein (RNP) complexes to combat various diseases, particularly neurodegenerative disorders like ALS, Alzheimer’s, and Huntington’s diseases. Traditional metho…
- College: College of Arts & Sciences
- Inventors: Bong, Dennis; Liang, Yufeng; Miao, Shiqin "Shiqin"; Strong, Rebekah
- Licensing Officer: Panic, Ana
Utilizing WT-IV-012 to improve immune checkpoint therapy in cancer treatment
TS-064262 — The Need
Addressing the limitations of current melanoma therapies, there exists a critical need for innovative approaches that enhance the effectiveness of immune checkpoint therapeutics. Despite advancements in immunotherapy, a significant percentage of melanoma patients do not achieve complete re…
- College: College of Arts & Sciences
- Inventors: Burd, Craig; Aguilar-Valenzuela, Renan; Burd, Christin
- Licensing Officer: Panic, Ana
Protecting Against Chemical Threats: A Revolutionary Solution
TS-044619 — The Need:
The threat of chemical weapons, such as sarin gas and VX, looms large in today's world. These organophosphorus (OP) nerve agents can cause rapid and devastating neurological damage, leading to paralysis, respiratory failure, and death. Current treatments, like oximes, are ineffective …
- College: College of Arts & Sciences
- Inventors: Hadad, Christopher; Callam, Christopher; Corrigan, Thomas; Dicken, Rachel; Dogan Ekici, Ozlem; Fitzpatrick, Keegan; Franjesevic, Andrew; McElroy, Craig; McKenney, Ryan; Muthukrishnan, Siva; Sanan, Toby; Vyas, Shubham; Yoder, Ryan; Young, Amneh "Amneh"
- Licensing Officer: Panic, Ana
Method to Synthesize Ceratamine A and B and Analogs Thereof
TS-030264 — A chemical process to produce ceratamine A and B.
The natural products ceratamines A and B were isolated from a marine sponge in minute quantities and shown to have potent anti-tumor activity. Due to the insufficient sample size and subsequent lack of availability of the producing sponge, evaluation was incomplete. Thus, the clinical potential ne…
- College: College of Arts & Sciences
- Inventors: Coleman, Robert "Rob"; Campbell, Erica
- Licensing Officer: Panic, Ana
