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A modified intein for temperature sensitive applications
TS-063697 — Controlled Protein Release Over a Broad Range of Temperatures
The Need: In the biotechnology field, the demand for efficient protein purification methods and innovative drug delivery solutions is ever-growing. Researchers and companies require technologies that can streamline the purification process, ensuring high yields and purity, while offering versatile …
  • College: College of Engineering (COE)
  • Inventors: Wood, David; Coolbaugh, Michael; Stimple, Samuel "Sam"; Yuan, Hongyu
  • Licensing Officer: Dahlman, Jason "Jay"

Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
  • Licensing Officer: Dahlman, Jason "Jay"

Revolutionizing Cancer Research: Unveiling the Dynamics of K-Ras for Targeted Therapies
TS-062433 — The Need: Understanding the intricate functions of the K-Ras protein is crucial in combating various types of human cancer. However, the lack of detailed atomic-level information has hindered progress in this area, leaving significant gaps in our comprehension of its roles in health and disease. Th…
  • College: Enterprise for Research, Innovation and Knowledge (ERIK)
  • Inventors: Bruschweiler, Rafael; Bruschweiler-Li, Lei "Lei"; Hansen, Alexandar "Alex"; Xiang, Xinyao; Yuan, Chunhua
  • Licensing Officer: Dahlman, Jason "Jay"

Ion Carpet-Based Surface-Induced Dissociation Device
TS-062342 — The Need In the field of mass spectrometry (MS), the study of proteins and protein complexes in their native form, known as native MS, has become crucial in understanding their structure and function. However, the current collision-induced dissociation (CID) technique used in tandem MS experiments …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Gilbert, Joshua; Stiving, Alyssa
  • Licensing Officer: Dahlman, Jason "Jay"

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