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Machine Learning Aided Concentration Prediction of Organic Compounds in the Sea Surface Microlayer by Vibrational Spectroscopic Methods
TS-064832 — The Need: The chemical composition of the sea surface microlayer (SSML) plays a crucial role in various environmental processes, impacting atmospheric chemistry and oceanic dynamics. However, traditional analytical methods struggle to efficiently characterize the complex and variable composition of …
  • College: College of Arts & Sciences
  • Inventors: Allen, Heather; Enders, Abigail; North, Nicole
  • Licensing Officer: Willson, Christopher

Semi-automatic extraction of georeferenced building data from historic Sanborn Fire Atlas maps
TS-064831 — The Need: Urban historians, city planners, and preservationists require efficient tools to extract building-level information from historic Sanborn Fire Insurance maps, essential for understanding urban development over time. However, manual extraction is time-consuming and impractical due to the sh…
  • College: College of Arts & Sciences
  • Inventors: Miller, Harvey; Li, Jialin; Lin, Yue; Logan, Gerika; Porr, Adam; Xiao, Ningchuan
  • Licensing Officer: Willson, Christopher

Earth-Abundant Transition Metal Catalysts for Sustainable Hydrofunctionalization Reactions
TS-064828 — The Need: Transition metal-catalyzed hydroelementation reactions address a critical demand in various industries by facilitating the addition of H-E (E = H, Si, B) across C-C double bonds. These reactions are vital in the chemical sector, particularly in the petrochemical, pharmaceutical, agrochemic…
  • College: College of Arts & Sciences
  • Inventors: Thomas, Christine; Fitzsimmons, Matthew
  • Licensing Officer: Willson, Christopher

Metalloproteins as a tunable scaffold for constructing quantum bits and dits for use in quantum information storage and processing
TS-064827 — The Need: As the second quantum revolution progresses, the demand for robust quantum materials intensifies, particularly in the realm of quantum computation and information processing. Addressing the challenges of coherence and stability in qubits is crucial for advancing quantum technology towards …
  • College: College of Arts & Sciences
  • Inventors: Shafaat, Hannah "Hannah"; Johnston-Halperin, Ezekiel; Teptarakulkarn, Pathorn
  • Licensing Officer: Willson, Christopher

Methods to improve the jitter and time walk of integrated constant fraction discriminators
TS-064826 — The Need Accurate measurements of energy and time-of-arrival of photons, particles, or ionizing radiation are crucial for identifying individual particles and enhancing spatial and temporal resolution in various systems. Technologies such as Light Detection and Ranging (LiDAR), positron emission to…
  • College: College of Arts & Sciences
  • Inventors: Kagan, Harris; Abusareya, Mo'men; Khalil, Waleed; Smith, Dale "Shane"
  • Licensing Officer: Willson, Christopher

Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
  • College: College of Arts & Sciences
  • Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
  • Licensing Officer: Willson, Christopher

Speech Corpus of Regional Dialect
TS-064586 — Speech corpus of regional dialect variation in American English documenting changing pronunciation patterns across several generations of speakers ranging in age from 8 to 101 years old. The Need The speech corpus can be used for research on variation and change in spoken language, for the deve…
  • College: College of Arts & Sciences
  • Inventors: Jacewicz, Ewa; Fox, Robert
  • Licensing Officer: Willson, Christopher

COLMARppm: web-server tool for prediction of NMR chemical shifts
TS-064585 — COLMARppm offers a swift and accurate solution to the longstanding challenges in metabolomics research. Unique features and capabilities position it as a crucial tool for researchers seeking to unlock unknown metabolites, contributing to health research The Need In the field of metabolomics resear…
  • College: College of Arts & Sciences
  • Inventors: Bruschweiler, Rafael; Li, Dawei "Dawei"; Rigel, Nick
  • Licensing Officer: Willson, Christopher

Intracellular Targeting by Monoclonal Antibodies
TS-064581 — Antibodies are essential therapeutic modalities for treating a plethora of different diseases, ranging from cancer, autoimmune disorders, degenerative diseases, and inflammation. The FDA approved the first antibody over three decades ago, and since more than 570 have been studied in clinical trials,…
  • College: College of Arts & Sciences
  • Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
  • Licensing Officer: Willson, Christopher

Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
  • Licensing Officer: Willson, Christopher

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