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Methods and Apparatus to Improve MRI Efficiency
TS-062627 — Magnetic Resonance Imaging (“MRI”) is one of the most important modern medical imaging modalities. It has far less risk of side effects than most other imaging modalities. Generally, a high quality image requires high signal-to-noise ratio, high contrast between normal and pathological t…
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua
  • Licensing Officer: Panic, Ana

LRC-Circuit Based Smart Jewelry for Detection of Multiple Biomarkers in Sweat
TS-062489 — Biosensors are a powerful and emerging technology capable of measuring the presence and concentration of molecules inside the human body. These devices are based on the premise that the physiology of diseased tissue is substantially different from that of healthy tissue and can be used to diagnose a…
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Liu, Tzu Li
  • Licensing Officer: Ashouripashaki, Mandana

"Flexible biomarker biofluid cell array for 2D/3D mapping of biomarker concentration levels"
TS-062483 — Measurement/detection of analytes (e.g., biomarkers) in different environments (e.g., biofluids/organs) is typically performed using a biosensor. Available bio-integrated sensors do not provide the capability to map biomarker concentrations, require a power source to function, use a limited number of electrodes, and normally can only measure a specific type of biofluid but not others. The use of glutamate mapping technology (radioactive or fluorescent ligand bound to a glutamate receptor) has been evaluated and found to require bulky/expensive medical equipment, a power source for measurement, cannot be miniaturized or integrated into a bio tissue, and require patients to be stationary during measurement.
The Need To address concerns and limitations with current biomarker detection/ measurement technologies, an alternative, cost-effective, efficient biosensing system/device capable of 2D/3D mapping the concentrations of various biomarkers in different bio environments is required. The Technology …
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Liu, Tzu Li; Nithianandam, Prasad
  • Licensing Officer: Ashouripashaki, Mandana

MRI Transmit Field Estimation in K-space Domain
TS-062329 — The Need: Medical imaging plays a crucial role in diagnosing various diseases, and Magnetic Resonance Imaging (MRI) has emerged as one of the most important imaging modalities due to its safety and effectiveness. Unlike other imaging methods that use ionizing radiation, MRI poses far fewer risks to …
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; Ding, Yu
  • Licensing Officer: Panic, Ana

Optimizing Magnetic Resonance Imaging (MRI) protocols
TS-062328 — The Need Medical imaging plays a crucial role in modern healthcare, aiding in the accurate diagnosis and treatment of various diseases. Magnetic Resonance Imaging (MRI) is a widely used non-invasive imaging modality that offers significant advantages over other techniques due to its lack of ionizin…
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; He, Lili; Lu, Zhong-Lin; Parikh, Nehal
  • Licensing Officer: Dahlman, Jason "Jay"

Optimization of 3D Magnetization-Prepared Rapid Gradient-Echo (MPRAGE) Sequence in Magnetic Resonance Imaging (MRI)
TS-062310 — The Need Medical imaging plays a crucial role in diagnosing various diseases and conditions. Magnetic Resonance Imaging (MRI) has emerged as one of the most significant and preferred medical imaging modalities due to its non-invasive nature and low risk of side effects compared to other imaging met…
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; Lu, Zhong-Lin
  • Licensing Officer: Dahlman, Jason "Jay"

Correcting Signal Inhomogeneity in Magnetic Resonance Imaging (MRI)
TS-062309 — The Need: Signal intensity inhomogeneity in Magnetic Resonance (MR) imaging presents a significant challenge, leading to degradation in image quality, obstructed diagnoses, reduced accuracy in quantitative analyses, and increased inter-scanner variability. The lack of effective inhomogeneity correct…
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; Constable, Robert; Lu, Zhong-Lin
  • Licensing Officer: Dahlman, Jason "Jay"

Accurate Characterization of Signal Coil Receive Sensitivity in Magnetic Resonance Imaging (MRI)
TS-062307 — The Need: Accurate characterization of receiver sensitivity is crucial for magnetic resonance imaging (MRI) techniques, particularly fast MRI using multi-channel coils. Different coils sample various parts of the k-space simultaneously during parallel MRI, and the final image's accuracy depends …
  • College: College of Arts & Sciences
  • Inventors: Wang, Jinghua; Lu, Zhong-Lin
  • Licensing Officer: Dahlman, Jason "Jay"

A lightweight, miniaturized, and portable readout circuits for tracking LRC-based wireless sensor
TS-061832 — A portable and lightweight readout circuit designed for use with LRC-based wireless sensors and in conjunction with other commonly used devices (e.g., smartphone, laptop, and tablet)
The Need Conventional vector network analyzers are bulky and expensive and tend to limit the ability to be used for daily tracing or high-frequency health status tracking in people. To overcome this and other limitations present in the cumbersome designs of today, compact-sized devices that take ad…
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Liu, Tzu Li
  • Licensing Officer: Ashouripashaki, Mandana

a Wireless, pH Regeneratable, Chemical Species Electronic Bio-Sensor
TS-058251 — Diagnostic tools are key to medicine, research and diagnostics. The measurement of biomolecules and their absorption kinetics can facilitate a better understanding of drug intake, biological responses, or in the continuous monitoring of specimen. Current equipment requires centralized equipment, t…
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Chen, Shulin; Liu, Tzu Li
  • Licensing Officer: Ashouripashaki, Mandana

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