Available Technologies
# of Displayed Technologies: 9 / 9
Innovative Small Molecule Inhibitors for Effective Treatment and Prevention of Coronavirus Infections
TS-066750 —
The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has significantly impacted global health and economies. Despite vaccine efforts, issues such as vaccine hesitancy, delays in distribution, and emerging variants have highlighted the need for effective therapeutic interventions. These i…
- College: College of Veterinary Medicine
- Inventors: Sharma, Amit; Li, Pui-Kai "Tom"; Xing, Enming
- Licensing Officer: Willson, Christopher
Addressing the Challenges in HCC Treatment with Innovative Technology
TS-062690 — Novel niclosamide analogues with improved bioavailability and mitigated dose-limiting toxicities.
Hepatocellular carcinoma (HCC) poses a significant global health challenge, being a predominant form of liver cancer with high mortality rates. The disease exhibits sexual dimorphism, disproportionately affecting males.
The Need
Despite the crucial role of androgen receptors (AR) in HCC progress…
- College: College of Pharmacy
- Inventors: Coss, Christopher; Cheng, Jeffrey; Cheng, Xiaolin; Kulp, Samuel; Li, Tom; Montgomery, Emma; Xing, Enming
- Licensing Officer: Willson, Christopher
Dual Androgen Receptor/AKR1C3 Inhibitors for Prostate Cancer
TS-062605 — The Need:
Castration-resistant prostate cancer (CRPC) poses a significant challenge in oncology, with existing therapies often leading to resistance and disease progression. Key drivers of resistance include the androgen receptor (AR) and aldo-keto reductase family 1 member C3 (AKR1C3). Novel treat…
- College: College of Pharmacy
- Inventors: Li, Pui-Kai "Tom"; Cheng, Xiaolin; Kong, Xiaotian; Xing, Enming
- Licensing Officer: Schworer, Adam
Primers and Probe for the Detection of Maize Chlorotic Mottle Virus (MCMV)
TS-062260 — The Need:
Efficient and accurate diagnosis of maize lethal necrosis (MLN)-causing viruses is essential for MLN surveillance programs and testing seed for zero tolerance of Maize chlorotic mottle virus (MCMV) in seed lots. To effectively manage MLN in both farmers' fields and commercial seed fie…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Miller, Sally; Baysal-Gurel, Fulya; Ma, Xing; Redinbaugh, Margaret "Peg"
- Licensing Officer: Dahlman, Jason "Jay"
A liposomal subunit flu vaccine formulation
TS-062211 — The Need: Addressing the Limitations of Current Flu Vaccines
Influenza epidemics and pandemics present significant challenges to public health and global economies. Existing flu vaccines are strain-specific, providing limited cross-protective immunity and often lack long-term effectiveness. Additio…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Gourapura, Renukaradhya; Carson, Kennith; Cheng, Xingguo; Dhakal, Santosh; Lee, Chang Won; McDonough, Joseph
- Licensing Officer: Dahlman, Jason "Jay"
3DScope: Detecting 3D Model Clones
TS-057129 — Algorithm for extracting 3D models, indexing them using a value-insensitive normalization algorithm, and comparing the model indexes to detect cloned 3D models.
The unauthorized copying of 3D models robs designers of property, reduces innovation going into the creation of 3D models, creates liability for entities unknowingly using copied models, and indicates a lapse in IP security. With the vast amount of 3D assets in use, it is infeasible for humans to …
- College: College of Engineering (COE)
- Inventors: Zuo, Chaoshun; Lin, Zhiqiang
- Licensing Officer: Mess, David
Combustion Looping Using Chemical Oxygen Carriers
TS-037590 — A two-stage process that can utilize a number of solid, liquid, or gaseous carbon-based fuels to produce hydrogen gas
Hydrogen gas can be produced from many different feedstocks, such as natural gas, biomass, or water, using a number of different techniques, such as steam methane reformation (SMR). Hydrogen production from coal gasification and manufacturing of hydrogen by the reduction of steam using a metal spe…
- College: College of Engineering (COE)
- Inventors: Fan, Liang-Shih; Gupta, Puneet; Li, Fanxing; Thomas, Theodore; Velazquez-Vargas, Luis
- Licensing Officer: Ashouripashaki, Mandana
Referenceless and Frequency Independent Radio Reciever
TS-037378 — A radio receiver that operates without the need for locally generated reference signals.
A radio frequency signal may typically consist of a single frequency carrier signal, modulated with some information signal. The purpose of a receiver is to extract the information signal from the carrier. This is commonly accomplished by mixing the received signal with one or more local reference…
- College: College of Engineering (COE)
- Inventors: Novak, Markus; Bojja venkatakrishnan, Satheesh; Volakis, John
- Licensing Officer: Zinn, Ryan
Multichannel Polymer Chips for Rapid Multiplex Enzyme-Linked Immunosorbent Assay
TS-014978 — A more accurate, cost efficient and faster method to one of the most widely used diagnostic tests in the world.
The conventional Enzyme-Linked Immunosorbent Assay, or ELISA, is typically carried out in a 96-well or 384-well microliter plate. The method involves a series of mixing and washing steps, which are not only tedious and laborious, but which also often result in large errors and inconsistent outcome…
- College: College of Engineering (COE)
- Inventors: Yang, Shang-Tian "ST"; Bai, Yunling; Huang, Wei-Cho
- Licensing Officer: Panic, Ana
