Small Molecule USP30 Inhibitors for the Treatment and Prevention of Cardiomyopathy
TS-066773 — The Need
Cardiomyopathy, a disease of the heart muscle, poses significant public health challenges due to its diverse causes, symptoms, and potential complications, including heart failure and arrhythmias. With cardiomyopathy often induced by drugs, such as anthracyclines used in chemotherapy, ther…
- College: College of Medicine (COM)
- Inventors: Sun, Nuo; Krigman, Judith; Yang, Mingchong; Zhang, Ruohan
- Licensing Officer: Willson, Christopher
Metal nitric oxides redox flow batteries
TS-066016 — The Need
Redox flow batteries (RFBs) offer a promising solution for storing intermittent renewable energy in the electrical grid. However, their reliance on finite and unsustainable transition metals, such as vanadium, poses significant sustainability challenges. The rising costs and environmental …
- College: College of Arts & Sciences
- Inventors: Zhang, Shiyu; Park, Jaehyun
- Licensing Officer: Randhawa, Davinder
Introducing HexaPro VSV: A Breakthrough in COVID-19 Vaccine Technology
TS-064191 —
The emergence of SARS-CoV-2 variants poses a significant challenge to existing COVID-19 vaccines, necessitating the development of a more durable and broadly protective solution. Current vaccines show reduced efficacy over time and struggle against Variants of Concern (VoCs) such as Omicron. Addre…
- College: College of Veterinary Medicine
- Inventors: Li, Jianrong; Chamblee, Michelle; Lu, Mijia; Zhang, Yuexiu
- Licensing Officer: Willson, Christopher
A next generation intranasal trivalent Measles, Mumps and Covid vaccine
TS-064189 — The Need
The current global landscape demands innovative solutions to address the urgent need for a safe and efficacious SARS-CoV-2 vaccine, particularly for the vulnerable population of infants and children under 12 years old. Existing vaccines face challenges in terms of durability, cost, and sta…
- College: College of Veterinary Medicine
- Inventors: Li, Jianrong; Xu, Jiayu; Zhang, Yuexiu
- Licensing Officer: Willson, Christopher
Aqueous Zn-Tetrazine Batteries
TS-064150 — The Need
As the global demand for energy storage devices continues to surge, the limitations of conventional lithium-ion batteries become increasingly evident. Dwindling lithium reserves are unable to meet the burgeoning needs of modern society, necessitating the exploration of alternative solution…
- College: College of Arts & Sciences
- Inventors: Zhang, Shiyu; Walter, Christopher
- Licensing Officer: Randhawa, Davinder
Metal Matrix Composites Reinforced by High Entropy Alloys
TS-063364 — Experience the future of advanced materials—our metal matrix composites offer a revo
lutionary approach to meeting the demands of modern industries. Elevate your products, enhance performance, and reduce costs with our groundbreaking technology.
For a closely related technology, please visit https://oied.osu.edu/find-technologies and type "T2017-051" in the search field.
In the aerospace, defense, and automotive industries, there is a pressing demand for advanced materials that combine low weight, high strength, exceptional wear resistance, and superior high-temperature performance. Traditional methods using ceramic particles as reinforcements in aluminum matrix c…
- College: College of Engineering (COE)
- Inventors: Luo, Alan; Huang, Xuejun; Zhang, Jianyue
- Licensing Officer: Zinn, Ryan
Live Attenuated Mumps Virus-Based SARS-CoV-2 Vaccines for Infants and Children
TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children
The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public health challenges worldwide. The pressing dema…
- College: College of Veterinary Medicine
- Inventors: Li, Jianrong; Boyaka, Prosper; Lu, Mijia; Zhang, Yuexiu
- Licensing Officer: Willson, Christopher
Novel method for attenuating live vaccine candidates for non-segmented negative-sense RNA viruses
TS-062213 — The Need: Preventing Respiratory Syncytial Virus (RSV) Infection and Disease
Respiratory Syncytial Virus (RSV) is a highly prevalent and dangerous pathogen responsible for significant morbidity and mortality, particularly in infants, young children, and immunocompromised individuals. Despite its gl…
- College: College of Veterinary Medicine
- Inventors: Li, Jianrong; He, Chuan; Lu, Mijia; Niewiesk, Stefan; Peeples, Mark; Xue, Miaoge; Zhang, Zijie; Zhao, Boxuan
- Licensing Officer: Willson, Christopher
High Efficiency LED Designs Using Quantum Well Engineering
TS-057127 — Achieving high efficiency LEDs with green, amber and longer wavelengths using III-nitride/II-IV-nitride heterostructures as the active media.
Although extensive research and development over the past two decades has resulted in close to 100% external quantum efficiency (EQE) of InGaN based blue light emitting devices, efficiency of the longer visible wavelength emitting devices has remained relatively low. Spontaneous polarization origi…
- College: College of Engineering (COE)
- Inventors: Zhao, Hongping; Zhang, Kaitian
- Licensing Officer: Randhawa, Davinder
Protecting Bluetooth Low Energy from Address Tracking When Using Whitelisting
TS-052807 —
Bluetooth Low Energy (BLE) is ubiquitous today due to its extremely low energy consumption and relatively large communication coverage. However, the devices communicated through Bluetooth are subject to address tracking attacks, where a nearby attacker can associate Bluetooth addresses to particul…
- College: College of Engineering (COE)
- Inventors: Lin, Zhiqiang; Zhang, Yue
- Licensing Officer: Mess, David
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