Available Technologies
# of Displayed Technologies: 10 / 206
Applied Category Filter (Click To Remove): Life & Health Sciences
A new modular format for bispecific antibody fragments
TS-068425 — Functionalization of scFvs with cyclic peptide linkers
The Need
The high specificity of antibodies has been utilized to develop numerous technologies, tools and therapeutics, like ADCs and radiopharmaceuticals. Engineered antibody fragments like single-chain variable fragments (scFvs) are starting to see their way into the clinic in BiTEs and CAR T. Sc…
- College: College of Arts & Sciences
- Inventors: Magliery, Thomas; Do, Jamie; Han, Jeong Min "Mina"; Zhu, Ian
- Licensing Officer: Dahlman, Jason "Jay"
Noninvasive Rapid Radiation Exposure Assay
TS-068290 — The Need
Radiation exposure poses significant health risks, including cancer and other illnesses, making it crucial for clinicians to accurately measure and assess the extent of radiation exposure. Existing methods often require invasive procedures and may not detect exposure at lower dose ranges.
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- College: College of Arts & Sciences
- Inventors: Schultz, Zachary; Jacob, Naduparambil; Morder, Courtney; Witte, Spencer
- Licensing Officer: Panic, Ana
RAFT Agents for Controlled Radical Polymerization of Biofunctionalized Polymeric Materials
TS-068081 — These RAFT agents enable synthesis of novel polymer materials with enhanced biocompatibility and tailored functionality, suited for a wide range of biomedical applications.
Background
The growing demand for biofunctionalized polymer materials in fields such as drug delivery and diagnostics requires precise control over polymer properties. However, current reagents for Reversible Addition Fragmentation chain Transfer (RAFT) polymerization struggle with achieving the ne…
- College: College of Arts & Sciences
- Inventors: Kulkarni, Anuja; Watkins, Davita
- Licensing Officer: Panic, Ana
Wearable Coils for Monitoring Human Body Kinematics
TS-067943 — Monitoring human physiological functions and performance during real-time activities is becoming increasingly popular in sporting and healthcare environments. Many studies now suggest that the quantitative evaluation of kinetic parameters, joint range of motion, heart rate, and breathing rate can be…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; Mishra, Vigyanshu
- Licensing Officer: Randhawa, Davinder
Non-Contact Magnetocardiography for Measuring Cognitive Workload
TS-067810 — Work environments and other brain-intensive activities impose high demands on the cognitive and cerebral resources required to process vast amounts of information. This high demand can expose individuals to cognitive overload, which can be dangerous for their health and lead to errors and accidents.…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; Zhu, Keren
- Licensing Officer: Randhawa, Davinder
Neonatal Blood Vessel Locator for Vascular Access Procedures
TS-067796 — A handheld device for identifying preterm blood vessels in neonatal ICU.
Over 300,000 preterm births in the United States occur annually, representing 10.5% of all live births. Most preterm births occur spontaneously, but some result from medical conditions like infections or pregnancy complications requiring early labor induction or cesarean delivery. Common causes of p…
- College: College of Engineering (COE)
- Inventors: Metzler, Sandra; Bresolin, Alejandro; Crawford, Mackenzie; Fernandes, Siddharth; Hardin, Rene; Patel, Aarti; Richards, Hannah; Trainor, Dylan
- Licensing Officer: Zinn, Ryan
Optimal and Pure Leaf Classification Trees for Machine Learning (ML) Decision-Making
TS-067550 — A method to improve the performance and accuracy of ML-based decision trees.
Decision trees are popular machine learning (ML) methods used in classification and regression problems, and they have numerous applications in the real world. Various industries use decision trees to help decide strategies, investments, and operations. In addition, they are used in healthcare to he…
- College: College of Engineering (COE)
- Inventors: Allen, Theodore; Arrey, Evelyn; Booth, Matthew; Liu, Enhao; Mashayekhi, Medhi
- Licensing Officer: Zinn, Ryan
Endoscopic additive manufacturing of conductors and wireless implants
TS-067045 — The Need
Wireless implants with integrated antennas are highly desirable for diagnostic, therapeutic, and monitoring applications due to their ability to communicate directly with external devices. However, the need for major surgical incisions to implant these devices poses significant risks, incl…
- College: College of Engineering (COE)
- Inventors: Kiourti, Asimina; Dontha, Balaji; Hoelzle, David; Li, Jinghua; Moulod, Mohammad
- Licensing Officer: Randhawa, Davinder
Dust Analysis: A Novel Approach to Monitoring Viral Spread
TS-066962 — The Need
Viral disease surveillance (e.g. influenza, SARS-CoV-2) in high-risk settings faces several challenges, such as asymptomatic carriers, incomplete reporting, resource limitations, and delayed diagnosis of traditional swab test methods. These challenges could allow a virus to silently spread…
- College: College of Engineering (COE)
- Inventors: Dannemiller, Karen; Faith, Seth; Hull, Natalie; Nastasi, Nick; Renninger, Nicole
- Licensing Officer: Ashouripashaki, Mandana
Color Correction System for Accurate Colorimetric Smartphone Measurements
TS-066957 — The Need
Colorimetric tests and remote image analysis are used in a wide range of industrial and medical applications. Digital image-based measurements made with smartphones are a promising platform to quantify colors at low cost, but suffer from inconsistency and errors caused by lens quality, sen…
- College: College of Engineering (COE)
- Inventors: Dannemiller, Karen; Panescu, Jenny; Qin, Rongjun; Song, Shuang; Zhang, Guixiang
- Licensing Officer: Ashouripashaki, Mandana
