Available Technologies
# of Displayed Technologies: 9 / 9
Applied Category Filter (Click To Remove): Animal Models
Specific Pathogen Free Turkey Eggs
TS-065846 — The Need: With the persistent threat of avian diseases, ensuring the health and safety of turkey populations is of utmost importance to the poultry industry. Traditional methods of disease prevention have limitations, necessitating a technology that can reliably produce Specific Pathogen Free (SPF) …
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Saif, Mo
- Licensing Officer: Panic, Ana
Generation of T cell-specific CXCR3 Transgenic mouse
TS-062320 — The Need: Addressing Susceptibility to Cutaneous Leishmaniasis
Cutaneous leishmaniasis, caused by the intracellular parasite Leishmania major and transmitted by sand flies, poses a significant threat to susceptible populations. This disfiguring disease results in large skin lesions, impacting both …
- College: College of Arts & Sciences
- Inventors: Satoskar, Abhay; Oghumu, Steve
- Licensing Officer: Dahlman, Jason "Jay"
Avian Genome Editing Advancements- Improving production efficiency
TS-062249 — The Need: Unlocking Avian Genetic Potential
The poultry industry plays a crucial role in meeting the growing demand for protein-rich food worldwide. However, avian genetic research has been limited by the complexity of editing avian genomes efficiently. Conventional methods utilizing primordial ger…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Lee, Kichoon "Kichoon"; Lee, Joonbum
- Licensing Officer: Dahlman, Jason "Jay"
Understanding Dynamics of the Gut- Germ-free cockroach model animal
TS-062239 — The Need:
In today's rapidly evolving world, understanding complex biological processes and their implications has become crucial for various industries, including agriculture, pharmaceuticals, and environmental conservation. Researchers and practitioners seek innovative reseach tools that can …
- College: College of Arts & Sciences
- Inventors: Sabree, Zakee; Jahnes, Benjamin "Ben"
- Licensing Officer: Dahlman, Jason "Jay"
DAT-CI knock-in mouse model carrying a modified dopamine transporter that maintains the transport function but resistant to cocaine inhibition and thus showing no rewarding cocaine effects
TS-058669 — A knock-in mouse model carrying a modified dopamine transporter that is resistant to cocaine inhibition and thus showing no rewarding cocaine effects.
Cocaine abuse has been an issue in the United States since the late 1980s. The highly addictive qualities along with the low cost ruined people’s lives and destroyed communities. Naloxone (marketed as Narcan) is highly effective but can only be used in the event of an overdose. Therefore, th…
- College: College of Medicine (COM)
- Inventors: Gu, Howard
- Licensing Officer: Schultz, Teri
NET-CI knock-in mouse model with a modified norepinephrine transporter carrying triple mutations that maintains the transport function and makes the transporter protein resistant to cocaine and antidepressants
TS-058668 — A knock-in mouse model with a modified norepinephrine transporter carrying triple mutations that makes the transporter protein resistant to cocaine and antidepressants.
Cocaine abuse has been an issue in the United States since the late 1980s. Furthermore, antidepressants also quite dangerous, with nearly 14% of users (who have bipolar disorder) experiencing dependence. Naloxone (marketed as Narcan) is highly effective but can only be used in the event of an over…
- College: College of Medicine (COM)
- Inventors: Gu, Howard
- Licensing Officer: Schultz, Teri
Rabbit Model for Duchenne Muscular Dystrophy
TS-058084 — A rabbit model has been created for Duchenne Muscular Dystrophy (DMD) that more closely resembles the effects experienced in humans while being more cost effective compared to larger animal models.
There has yet to be a DMD animal model that bridges the gap between cost effectiveness and scientific relevance. This new rabbit model does that.
DMD is a lethal genetic disease characterized by progressive muscle weakness and muscle wasting. There are several animal models for DMD, includin…
- College: College of Medicine (COM)
- Inventors: Han, Renzhi
- Licensing Officer: Schworer, Adam
A novel mouse model of spontaneous chronic lymphocytic leukemia
TS-055268 — The laboratory of Dr. Rosa Lapalombella in collaboration with Dr. James Blachly at The Ohio State University has developed a mouse model of spontaneous Chronic Lymphocytic Leukemia.
The Need
Chronic lymphocytic leukemia (CLL) accounts for one quarter of new cases of leukemia. CLL is the most prevalent adult leukemia in Western countries and is characterized by a mature B-cell phenotype. Given the burden of this disease, a large pipeline of drugs for treatment are in progress…
- College: College of Medicine (COM)
- Inventors: Lapalombella, Rosa; Blachly, James; Byrd, John
- Licensing Officer: Schworer, Adam
CXCR3-GFP knock-in mouse
TS-038221 — A knock-in murine model that expresses high levels of GFP in CXCR3 positive cells.
Chemokines are typically small, secreted molecules that participate in leukocyte trafficking, recruitment, and activation. They also play roles in normal and pathological processes including allergic responses, infectious and autoimmune disease, angiogenesis, inflammation, and tumor growth and met…
- College: College of Arts & Sciences
- Inventors: Satoskar, Abhay; Oghumu, Steve
- Licensing Officer: Dahlman, Jason "Jay"
