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MicroRNA profile predicts colon cancer prognosis
TS-065453 — The Need: Colon cancer remains one of the most prevalent and lethal forms of cancer worldwide. Timely and accurate diagnosis is critical for effective treatment and improved patient outcomes. Current diagnostic methods often lack the precision and sensitivity needed for early detection and prognosi…
  • College: College of Medicine (COM)
  • Inventors: Croce, Carlo
  • Licensing Officer: Schultz, Teri

Scalable Nanoparticle Synthesis for Precision Applications
TS-064181 — In the rapidly evolving landscape of nanotechnology, there exists a critical demand for scalable and efficient methods of producing nanoparticles. Current approaches, often confined to small-scale batches, hinder the widespread implementation of nanomaterials in diverse fields such as medicine, bi…
  • College: College of Engineering (COE)
  • Inventors: Winter, Jessica; Ruan, Gang
  • Licensing Officer: Dahlman, Jason "Jay"

Unveiling Biochemically Responsive MR Probes for Precision Beyond Limits
TS-064179 — In the realm of medical diagnostics, the need for precise and non-invasive detection of molecular-level pathology has been a longstanding challenge. Traditional imaging techniques often fall short in providing detailed insights into biological processes at this scale. To address this gap, there is…
  • College: College of Arts & Sciences
  • Inventors: Shafaat, Hannah "Hannah"
  • Licensing Officer: Dahlman, Jason "Jay"

A new diagnostic assay for classic galactosemia
TS-064133 — Classic galactosemia is a genetic condition that can lead to life-threatening complications, including feeding problems, failure to thrive, liver damage, bleeding, and sepsis. If a lactose-restricted diet is provided during the first ten days of life, the neonatal symptoms quickly resolve and reduce…
  • College: College of Arts & Sciences
  • Inventors: Gopalan, Venkat; Bashian, Eleanor; Thirugnanasambantham, Pankajavalli
  • Licensing Officer: Panic, Ana

Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents
TS-062548 — The Need: Enhancing Surgical Precision with Anti-TAG-72 Imaging Agents Colorectal carcinoma is a significant medical challenge, with a high incidence rate in the USA. Current surgical approaches, along with external imaging technologies, have limitations in accurately detecting cancerous tissues, l…
  • College: College of Medicine (COM)
  • Inventors: Gong, Li; Tweedle, Michael
  • Licensing Officer: Willson, Christopher

Functional "fingerloop" DNA antisense motifs for nucleic acid targeting and detection technologies
TS-062547 — The Need: The field of molecular biology and genetic engineering faces challenges in achieving precise and accurate detection and amplification of target nucleic acid sequences. Traditional hybridization technologies suffer from the issue of mismatched targets, leading to reduced specificity and rel…
  • College: College of Arts & Sciences
  • Inventors: Lease, Richard
  • Licensing Officer: Dahlman, Jason "Jay"

Addressing the Challenges in Cancer Imaging
TS-062545 — The Need: Addressing the Challenges in Cancer Imaging Cancer continues to be a major cause of global mortality, with over 10% of all deaths attributed to this devastating disease. Despite significant advancements in cancer research, there remains a critical need to enhance current techniques for pr…
  • College: College of Arts & Sciences
  • Inventors: Magliery, Thomas; Long, Nicholas; Sullivan, Brandon
  • Licensing Officer: Dahlman, Jason "Jay"

Addressing the Challenges in Cancer Imaging
TS-062544 — The Need: Addressing the Challenges in Cancer Imaging Cancer continues to be a major cause of global mortality, with over 10% of all deaths attributed to this devastating disease. Despite significant advancements in cancer research, there remains a critical need to enhance current techniques for pr…
  • College: College of Arts & Sciences
  • Inventors: Magliery, Thomas; Allen, Heather; Alten, Edward; Hitchcock, Charles; Long, Nicholas; Martin, Edward; Sullivan, Brandon
  • Licensing Officer: Dahlman, Jason "Jay"

MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Solid Cancers
TS-062318 — The Need Cancer is a significant health problem and a leading cause of death in developed countries. Solid cancers, including prostate, breast, lung, stomach, colon, and pancreatic cancers, pose particularly challenging diagnostic and treatment obstacles. Early detection of these cancers is crucial…
  • College: College of Medicine (COM)
  • Inventors: Croce, Carlo; Calin, George; Volinia, Stefano
  • Licensing Officer: Willson, Christopher

Diagnostics and Prognostics of Prostate Cancer
TS-062299 — The Need: Addressing Prostate Cancer Diagnostics and Therapeutics Prostate cancer remains a significant challenge in medical diagnosis and treatment, requiring advancements in diagnostics, therapeutics, and prognostics. Current approaches fall short in providing accurate and effective solutions, le…
  • College: College of Medicine (COM)
  • Inventors: Croce, Carlo
  • Licensing Officer: Willson, Christopher

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