# of Displayed Technologies: 5 / 5

Applied Category Filter (Click To Remove): Biomarkers


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Diagnostic for Early Detection of Heart Damage
TS-059578 — A novel biomarker for the early identification of cardiac damage, including chemotherapy-induced cardiotoxicity.
Despite significant medical advances and technologies, cardiovascular disease remains the number one cause of death in the United States, irrespective of gender or race, resulting in more than 600,000 annual deaths. Additionally, while cancer survivorship has increased significantly, the number one …
  • College: College of Medicine (COM)
  • Inventors: Smith, Sakima; Dib, Patrick; McElroy, Craig
  • Licensing Officer: Csatary, Erika

SARS-CoV-2 Diagnostic Assay with Sensors of Immune Activation
TS-050296 — A sequencing-based diagnostic assay for SARS-CoV-2 with sensors of immune activation and the viral microbiota.
Diagnosis of SARS-CoV-2 infection, which is responsible for COVID-19 disease, is typically performed by molecular analysis of upper respiratory sampling (e.g. nasal swab). Transcriptional-mediated amplification (TMA) and quantitative (real-time) polymerase chain reaction (qPCR) using one or more v…
  • College: College of Medicine (COM)
  • Inventors: Jones, Daniel; Avenarius, Matthew; Tu, Huolin
  • Licensing Officer: Schworer, Adam

DNA-cage erasable labels for fluorescence-based imaging
TS-043819 — Compositions and methods for analyzing multiple biomarkers without damaging tissue.
Histopathology is a cornerstone of tissue analysis used to diagnose many clinical conditions. Many of these diagnoses are based on identifying the presence of specific biomarkers, which can be indicated by colored labels. Currently, only 1-2 markers can be analyzed per slide, reducing accuracy and…
  • College: College of Engineering (COE)
  • Inventors: Winter, Jessica; Jergens, Elizabeth; Lee, Kil Ho "Kilho"
  • Licensing Officer: Willson, Christopher

Paper-based Dried Blood Spheroids for Stabilization of Labile Organic Compounds Stored in Ambient Air
TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.
Dried blood spots on paper substrates offer a facile sample collection, storage, and transportation approach for biofluids. However, variable diffusion, volcanic effects, analyte instability, and difficulty in recovering samples from paper plague this method, lowering confidence in analyte quantif…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Damon, Deidre
  • Licensing Officer: Willson, Christopher

Fingerloop sRNA Nanotechnology for Metabolic Engineering and Synthetic Biology
TS-037383 — Functional "fingerloop" RNA antisense motifs for metabolic engineering and RNA nanotechnology applications.
The Need Synthetic biology holds tremendous promise to revolutionize how numerous products are made. For example, microorganisms can be harnessed to produce useful products such as biofuels, chemicals, therapeutics, fragrances, and antibodies, just to name a few examples. However, metabolic enginee…
  • College: College of Engineering (COE)
  • Inventors: Lease, Richard; Lahiry, Ashwin; Stimple, Samuel "Sam"; Wood, David
  • Licensing Officer: Willson, Christopher

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