Strain‑Activated Programmable Surfaces for Controlled Drug Delivery in Mechanically Regulated Diseases
TS-072945 —
Many mechanically mediated conditions such as vascular hypertension, glaucoma, and abdominal distension, present intermittent, unpredictable episodes that demand drug release only when symptoms emerge. Conventional platforms often leak at baseline, require external triggers, or cannot synchronize …
- College: College of Engineering (COE)
- Inventors: Zhao, Yi
- Licensing Officer: Randhawa, Davinder
Sustainable Fungal Memristors for Neuromorphic and Eco-Friendly Computing
TS-072329 — The Need
The rapid growth of artificial intelligence and neural networks is driving unprecedented demand for energy-efficient, scalable hardware. Conventional memristors require rare earths and complex fabrication, contributing to electronic waste and limiting accessibility. There is a critical need…
- College: College of Engineering (COE)
- Inventors: LaRocco, John; Hill, Justin; Simonis, John; Tahmina, Qudsia
- Licensing Officer: Randhawa, Davinder
Flexible Light-Addressable Sensor for High-Resolution Physiological Mapping
TS-072319 — The Need
Current methods for mapping electrical potential gradients in biological tissues, such as the brain, rely on high-density electrode arrays fabricated via costly microfabrication techniques. These rigid devices struggle to conform to complex tissue morphologies, limiting their effectiveness …
- College: College of Engineering (COE)
- Inventors: Li, Jinghua; Chen, Shulin; Jia, Yizhen; Liu, Tzu Li; Wang, Qi
- Licensing Officer: Ashouripashaki, Mandana
Wearable Magnetoinductive Smart Textiles for Real-Time Muscle Health Monitoring
TS-072052 — The Need
Current wearable sensors for muscle health are limited in their ability to track real-time geometric changes in muscle size and shape, especially outside controlled laboratory environments. Existing solutions, such as force myography and ultrasound, either lack direct geometric insight or a…
- College: College of Engineering (COE)
- Inventors: Coogle, Sam; Kiourti, Asimina
- Licensing Officer: Randhawa, Davinder
Breakthrough In Delivery: Expanding Access to Intracellular Targets for Next-Generation Therapies
TS-072004 — Empower your pipeline with a versatile platform for efficient, customizable biomolecule transport.
Overview
Intracellular delivery remains a persistent challenge in drug delivery, gene editing, and biotechnology. Pharmaceutical and biotech companies lose valuable opportunities when promising drugs and biologics cannot reach their intended targets inside cells, limiting product effectiveness and m…
- College: College of Arts & Sciences
- Inventors: Bong, Dennis
- Licensing Officer: Panic, Ana
Free Energy Spectroscopy: Transforming Molecular Analytics for Next-Generation Biotech and Pharma
TS-071946 — Powering faster, smarter decisions with real-time molecular insights for research and therapeutic development.
Overview
Pharmaceutical and biotech companies often face delays and uncertainty in new drug development due to insufficient experimental insight into the shifting behaviors of large biomolecular complexes— processes critical to understanding disease and drug mechanisms. Free Energy Spectrosco…
- College: College of Arts & Sciences
- Inventors: Poirier, Michael; Bonin, Kalven; Bundschuh, Ralf; Castro, Carlos
- Licensing Officer: Panic, Ana
Quantum Defect-Based Ultra-Sensitive Radiation Detection Platform
TS-071847 — The Need
Current fast neutron detection technologies suffer from inherently low sensitivity due to the limited interaction cross-section between neutrons and atomic nuclei. This restricts their effectiveness in critical applications such as nuclear security, radiation dosimetry, and advanced imaging…
- College: College of Engineering (COE)
- Inventors: Cao, Lei Raymond; Johnston-Halperin, Ezekiel; Shoen, Luke
- Licensing Officer: Ashouripashaki, Mandana
Smart Blueberry Extract: The Modern Natural Health Solution for Inflammation Relief and Wellness
TS-071830 — Unlocking plant-powered solutions to deliver effective inflammation relief and enhance disease outcomes.
Overview
Chronic inflammation driven by elevated interleukin-11 (IL-11) is a critical underlying cause of tissue scarring and cancer, worsening the disease outcomes over time. Current anti-inflammatory options fall short, offering limited control over IL-11 and failing to stop its persistent buildu…
- College: College of Food, Agricultural, and Environmental Sciences (CFAES)
- Inventors: Giusti, M. Monica; Prasher, Harmeen; Sellers, Patrick; Ziouzenkova, Ouliana
- Licensing Officer: Panic, Ana
Reversible Shape-Changing Amorphous Polymers via Liquid Crystal Templating
TS-071745 — The Need
Current two-way shape memory polymers (SMPs) require expensive, crystalline or liquid crystalline monomers and complex synthesis, limiting their use in cost-sensitive and biocompatible applications. Widely used amorphous polymers (e.g., polystyrene, PMMA) are inexpensive and common in con…
- College: College of Engineering (COE)
- Inventors: Wang, Xiaoguang "William"; Dupont, Robert; Zhang, Meng
- Licensing Officer: Randhawa, Davinder
NeuroThread: Ultrathin Wire-Type Neurochemical Sensor for Real-Time CNS Monitoring
TS-071414 — The Need
Current neurochemical monitoring technologies are limited by bulky form factors, complex fabrication, and invasiveness, which restrict their clinical and research utility. Existing sensors often cause tissue damage, lack real-time resolution, and are costly to manufacture, impeding widespre…
- College: College of Engineering (COE)
- Inventors: Li, Jinghua; Liu, Tzu Li
- Licensing Officer: Ashouripashaki, Mandana
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