Advanced Dual-Layer Compositions for Enhanced Delivery and Stability of Biologically Active Agents

The Need

In the realm of human and mammalian health, delivering biologically active components that are sensitive to moisture or other environmental factors has posed a significant challenge. Traditional methods, such as encapsulation or use of desiccants, often fall short in ensuring stability and targeted delivery, particularly for components like probiotics, vitamins, and other sensitive agents. Effective delivery mechanisms that protect these components from degradation in harsh environments, like the acidic stomach, while ensuring targeted release in specific intestinal locations, are urgently needed to advance treatment options for various conditions, including inflammatory bowel disease and irritable bowel syndrome.

The Technology

This innovative composition features an inner core surrounded by at least two protective layers, designed to maintain the integrity of moisture-sensitive components. The inner core contains the active ingredient, while the inner layer provides resistance to low pH environments, preventing degradation in acidic conditions. The outer hydrophobic layer further shields the core from moisture, enhancing stability and shelf life. This dual-layer approach ensures the safe delivery of probiotics, vitamins, and other sensitive biologically active agents to targeted areas in the gastrointestinal tract.

Commercial Applications

  • Oral delivery of probiotics for treating gastrointestinal conditions.
  • Encapsulation of moisture-sensitive vitamins for enhanced stability.
  • Targeted delivery of biologically active agents to specific intestinal locations.
  • Formulations for veterinary use in animals with similar health conditions.
  • Development of stable dietary supplements with extended shelf life.

Benefits/Advantages

  • Enhanced Stability: Dual-layer protection significantly improves the stability and shelf life of moisture-sensitive components.
  • Targeted Delivery: Ensures effective delivery to specific areas in the gastrointestinal tract, enhancing therapeutic efficacy.
  • Versatility: Suitable for a wide range of biologically active agents, including probiotics and vitamins.
  • Improved Efficacy: Prevents degradation in acidic environments, ensuring the active components remain effective upon delivery.
  • Commercial Viability: Offers a reliable solution for manufacturers seeking to develop stable and effective health products.

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