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Endoscopic additive manufacturing of conductors and wireless implants
TS-067045 — The Need Wireless implants with integrated antennas are highly desirable for diagnostic, therapeutic, and monitoring applications due to their ability to communicate directly with external devices. However, the need for major surgical incisions to implant these devices poses significant risks, incl…
  • College: College of Engineering (COE)
  • Inventors: Kiourti, Asimina; Dontha, Balaji; Hoelzle, David; Li, Jinghua; Moulod, Mohammad
  • Licensing Officer: Randhawa, Davinder

Novel Quantitative Method to Detect Mold Growth in Buildings
TS-066963 — The Need Exposure to mold in homes costs billions of dollars every year. Exposure is particularly harmful to the 8% of the United States population that suffers from asthma; a leading cause of disability in children. Currently, odor, visible mold growth, and dampness are the best indicators of mold…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Balasubrahmaniam, Neeraja; Bope, Ashleigh
  • Licensing Officer: Ashouripashaki, Mandana

Dust Analysis: A Novel Approach to Monitoring Viral Spread
TS-066962 — The Need Viral disease surveillance (e.g. influenza, SARS-CoV-2) in high-risk settings faces several challenges, such as asymptomatic carriers, incomplete reporting, resource limitations, and delayed diagnosis of traditional swab test methods. These challenges could allow a virus to silently spread…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Faith, Seth; Hull, Natalie; Nastasi, Nick; Renninger, Nicole
  • Licensing Officer: Ashouripashaki, Mandana

Smartphone Detection Kit for Airborne Formaldehyde and Allergens
TS-066960 — The Need Indoor air can be polluted by various sources, including building materials, furniture, cleaning products, and even people. Exposure to these resulting contaminants and allergens can lead to a variety of health problems, such as respiratory irritation, allergies, and even cancer. It is cur…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Parquette, Jonathan; Qin, Rongjun
  • Licensing Officer: Ashouripashaki, Mandana

Color Correction System for Accurate Colorimetric Smartphone Measurements
TS-066957 — The Need Colorimetric tests and remote image analysis are used in a wide range of industrial and medical applications. Digital image-based measurements made with smartphones are a promising platform to quantify colors at low cost, but suffer from inconsistency and errors caused by lens quality, sen…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Panescu, Jenny; Qin, Rongjun; Song, Shuang; Zhang, Guixiang
  • Licensing Officer: Ashouripashaki, Mandana

Unveiling the Nanoscale: Breakthrough Analytical Speed of Real-Time Super-Resolution Microscopy and Beyond
TS-066926 — This Ohio State University software innovation offers groundbreaking analytical speed and automation of Single-Molecule Localization Microscopy (SMLM) as well as analysis of 3D data and images extending beyond the field of microscopy. Our technology offers real-time spatial analysis in continuous and discrete space, enabling unprecedented speed and efficiency in data processing that translates into faster decision-making, high-throughput screening capabilities, and broad applicability beyond traditional microscopy.
Single-molecule localization microscopy (SMLM) describes a family of fast-evolving, powerful imaging techniques that dramatically improve spatial resolution over standard, diffraction-limited microscopy techniques and can image biological structures at the molecular scale. SMLM can now be performe…
  • College: College of Engineering (COE)
  • Inventors: Soltisz, Andrew; Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

Humanized SSTR2 mAb and ADC to target SSTR2+ tumors
TS-066912 — Targeted humanized mAbs and ADCs for cancer treatment
The Liu Lab Dr. Xiaoguang “Margaret” Liu applies her industry experience (Lonza, Merck, and Life Technologies) in cell line and process development towards her lab’s focus on targeted anti-cancer therapies including monoclonal antibodies, antibody-drug conjugates, and gene therapi…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xiaoguang "Margaret"; Zhou, Lufang
  • Licensing Officer: Schworer, Adam

Advanced Sensor Housing for Environmental Monitoring in Precision Agriculture and Beyond
TS-066793 — The Need In agriculture, the accurate measurement of gasses such as nitrous oxide (N2O) and nitrogen oxides (NOx) is crucial for optimizing fertilizer use, minimizing greenhouse gas emissions, and reducing air pollution. Current monitoring technologies are often expensive, complex, and not suitable…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Khanal, Sami; Bevers, Noah; Shearer, Scott; Tkach, Chris
  • Licensing Officer: Dahlman, Jason "Jay"

Small Molecule USP30 Inhibitors for the Treatment and Prevention of Cardiomyopathy
TS-066773 — The Need Cardiomyopathy, a disease of the heart muscle, poses significant public health challenges due to its diverse causes, symptoms, and potential complications, including heart failure and arrhythmias. With cardiomyopathy often induced by drugs, such as anthracyclines used in chemotherapy, ther…
  • College: College of Medicine (COM)
  • Inventors: Sun, Nuo; Krigman, Judith; Yang, Mingchong; Zhang, Ruohan
  • Licensing Officer: Willson, Christopher

Biofilm Detachment Monitoring for Enhanced Oral Health Solutions
TS-066772 — The Need Biofilms, particularly dental plaque-biofilms, are communities of microorganisms encased in a slimy extracellular polymeric substance (EPS) that adhere to surfaces or neighboring microorganisms. These biofilms are responsible for various infectious diseases, including oral diseases such as…
  • College: College of Medicine (COM)
  • Inventors: Stoodley, Paul; Gloag, Erin
  • Licensing Officer: Willson, Christopher

Innovative Biomarker Technology for Detecting and Treating Endothelial Injury in Neurological Disorders
TS-066771 — Endothelial injury is a significant pathological mechanism underlying various neurological disorders, including neurodegenerative, neuroinflammatory, and cerebrovascular diseases. Current clinical and research settings lack reliable biomarkers to detect or measure endothelial injury in the human C…
  • College: College of Medicine (COM)
  • Inventors: Al Tarawneh, Rawan
  • Licensing Officer: Willson, Christopher

Advanced Dual-Layer Compositions for Enhanced Delivery and Stability of Biologically Active Agents
TS-066770 — The Need In the realm of human and mammalian health, delivering biologically active components that are sensitive to moisture or other environmental factors has posed a significant challenge. Traditional methods, such as encapsulation or use of desiccants, often fall short in ensuring stability and…
  • College: Office of Business and Finance
  • Inventors:
  • Licensing Officer: Dahlman, Jason "Jay"

Advanced Mass Spectrometry Hybrid Ionization Technology for Comprehensive Molecular Analysis
TS-066752 — In today's fast-paced commercial and scientific environments, there is an increasing demand for precise and efficient analytical techniques capable of handling complex mixtures with diverse physicochemical properties. Existing ionization techniques like Electrospray Ionization (ESI) and Atmosp…
  • College: College of Arts & Sciences
  • Inventors: Badu-Tawiah, Abraham; Damale, Purva; Grooms, Alex; Kulyk, Dmytro
  • Licensing Officer: Dahlman, Jason "Jay"

Cell-Penetrating Peptides: Revolutionizing Intracellular Delivery
TS-066751 — In the rapidly evolving field of biotechnology and pharmaceuticals, there is a critical need for efficient delivery mechanisms to transport therapeutic agents directly into cells. Traditional methods face challenges with membrane impermeability and degradation of therapeutic compounds, limiting th…
  • College: College of Arts & Sciences
  • Inventors: Pei, Dehua
  • Licensing Officer: Dahlman, Jason "Jay"

Innovative Small Molecule Inhibitors for Effective Treatment and Prevention of Coronavirus Infections
TS-066750 — The ongoing COVID-19 pandemic, caused by the SARS-CoV-2 virus, has significantly impacted global health and economies. Despite vaccine efforts, issues such as vaccine hesitancy, delays in distribution, and emerging variants have highlighted the need for effective therapeutic interventions. These i…
  • College: College of Veterinary Medicine
  • Inventors: Sharma, Amit; Li, Pui-Kai "Tom"; Xing, Enming
  • Licensing Officer: Dahlman, Jason "Jay"

Revolutionary Modular Nuclear Reactor Core for Space Exploration
TS-066252 — Rotating Fuel Core with Fuel Strip(s) ("ROFFUS") is an innovative modular nuclear reactor core designed to provide reliable and scalable power for advanced space missions.
Future space missions require dependable, high-output energy sources to support operations such as material processing, transportation, and thermal conditioning, particularly in challenging environments like the lunar poles where sunlight is scarce. This advanced nuclear reactor core features a…
  • College: College of Engineering (COE)
  • Inventors: Smidts, Carol; Aldemir, Tunc; Cao, Lei Raymond; Horack, John; Khafizov, Marat
  • Licensing Officer: Zinn, Ryan

Advanced Sensor Arrays for Precise Gas Identification and Analysis
TS-066250 — A cutting-edge sensor system featuring p-n junctions in MOS materials for accurate detection and identification of gases.
In various industries, there is a growing demand for highly selective and sensitive gas sensors capable of accurately identifying specific gases within complex mixtures, addressing challenges in environmental monitoring, industrial safety, and healthcare diagnostics. This innovative sensor syst…
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Govindhan, Maduraiveeran; Mondal, Suvra; Sun, Chenhu
  • Licensing Officer: Zinn, Ryan

Revolutionary NO Sensor for Highly Selective and Sensitive Gas Detection
TS-066249 — A novel sensor leveraging WO3 and Cr2O3 for selective NO detection in harsh environments and breath analysis with high sensitivity at ppb levels.
There is a critical demand for advanced gas sensors capable of selectively detecting nitric oxide (NO) in diverse applications such as environmental monitoring, industrial processes, and medical diagnostics, particularly in challenging environments with interfering gases like carbon monoxide (CO).…
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Govindhan, Maduraiveeran; Mondal, Suvra; Sun, Chenhu
  • Licensing Officer: Zinn, Ryan

Metal oxide-based resistive type sensor for the detection of carbon monoxide at room temperature
TS-066246 — Our innovative CO sensor utilizes hydrated ruthenium oxide to detect carbon monoxide within a gas mixture with high sensitivity and selectivity at temperatures ranging from 25°C to 300°C.
Reliable and low-cost CO sensors with high sensitivity and selectivity are essential for environmental safety and industrial control, particularly to monitor combustion environments, automotive emissions, and various industrial processes, ensuring compliance with regulations and minimizing health …
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Adeyemo, Adedunni
  • Licensing Officer: Zinn, Ryan

Innovative High-Temperature NOx Sensor for Combustion Control
TS-066239 — There is a critical need for advanced high-temperature NOx sensors to accurately monitor and control combustion environments, ensuring compliance with government regulations and mitigating the harmful effects of NOx on ecosystems and public health. Our new NOx sensor is designed to detect total…
  • College: College of Arts & Sciences
  • Inventors: Dutta, Prabir; Yang, Jiun-Chan
  • Licensing Officer: Zinn, Ryan

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