# of Displayed Technologies: 20 / 246


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Self-assembled 3D RNA Cage Nanoparticles with Precise Shape and Size for Applications in Medical Sciences, Materials Sciences, Engineering and Nanotechnology
TS-039545 — Self-assembling, highly stable RNA cages amenable to custom functionalization and cargo delivery
One of the primary challenges in therapeutic development is cheap, efficient, and safe drug delivery to specific target tissues. To better target specific tissues, RNA nanotechnology has been progressively applied to generate predefined architectures via self-assembly of modular building blocks. N…
  • College: College of Pharmacy
  • Inventors: Guo, Peixuan; Jasinski, Daniel; Khisamutdinov, Emil; Li, Hui
  • Licensing Officer: Flammang, Ann Marie

RNA Nanotubes for Single Molecule Sensing and DNA/RNA/Protein Sequencing
TS-039514 — Stable, predictably ordered RNA nanopores for disease diagnosis and biopolymer sequencing.
New rapid and accurate sequencing methods, and disease detection methods are always in high demand. Newer advances in these areas include membrane-anchored structures and synthetics, which allow molecule idenfication and biopolymer sequencing by measuring conductance changes associated with passag…
  • College: College of Pharmacy
  • Inventors: Guo, Peixuan; Li, Hui; Wang, Shaoying
  • Licensing Officer: Flammang, Ann Marie

Sampling Method for Big Data Join Queries
TS-039364 — Tables of information are related using JOIN operators, a particular data point from table A is related with a data point from table B. This connectivity is a fundamental part of data analysis, allowing the user to run statistical analysis to find trends. When using large data sets too much inform…
  • College: College of Engineering (COE)
  • Inventors: Nandi, Arnab; Kamat, Niranjan
  • Licensing Officer: Wohlgamuth, Christopher

ICARUS: Interactive Cleaning and Rule System
TS-039363 — User friendly database validation software
Data sets are booming larger and more complex, in order to use big data ideas all the data must be stored in an organized manner. Data cleaning is the process of removing corrupted records from a set of data, with the problematic data being updated or removed. Data validation is the process of con…
  • College: College of Engineering (COE)
  • Inventors: Nandi, Arnab; Hebert, Courtney; Rahman, Protiva
  • Licensing Officer: Wohlgamuth, Christopher

Design and apparatus for quantification of the mapping of the sensory areas of the brain
TS-039164 — A new tool that can quantify the sensory maps of the human brain. The tool can be used to quantify plasticity and pathology in the sensory areas of the human brain that are associated with normal and abnormal development, aging, and diseases in sensory systems. The first application of the tool, on retinotopic maps of the visual cortex, has generated excellent results.
By analyzing the stimulus­-referred fMRI responses in each voxel of an MR image, retinotopic mapping of human visual cortex can generate cortical maps of the visual space. These maps elucidate the spatial organization of the neuronal responses to visual images. Although numerous studies have b…
  • College: College of Arts & Sciences
  • Inventors: Wang, Yalin; Lu, Zhong-Lin; Ta, Duyan
  • Licensing Officer: Norris, Francis "Frank"

Development of novel furano-parthenolides for human leukemia treatment
TS-038998 — Parthenolide analogues derived from plants could be effective in treating leukemia or supplementing other treatments.
The American Cancer Society estimates that in 2017 there will be about 1,688,780 new cancer cases diagnosed and 600,920 cancer deaths in the United States. Chemotherapy has improved, but further development is needed to improve the efficacy of this treatment, and cancers can develop multidrug resi…
  • College: College of Pharmacy
  • Inventors: Ren, Yulin
  • Licensing Officer: Flammang, Ann Marie

Productivity model for Advanced Practice Providers
TS-038991 — A new, well-rounded system of measuring APP productivity
Physician assistants (PAs) and nurse practitioners (NPs) are referred to as advanced practice providers (APPs). They are certified health care professionals that provide care and treatment to patients under a doctor's supervision. Although they are an integral part of many clinics and hospital…
  • College: OSU Wexner Medical Center
  • Inventors: Rosselet, Robin; Brom, Heather; Butz, Jenna; Cackler, Scott; Chen, Ting; Kent, Kelly; Kipp, Kris; Suwignjo, Ronny
  • Licensing Officer: Flammang, Ann Marie

A prototype device for applying beneficial mites to a greenhouse crop
TS-038983 — A method of evenly distributing beneficial mites throughout a greenhouse using a novel device.
Beneficial insects and mites feed on plant pests to improve overall plant health in greenhouses. Also called "biological controls," these mites are a valuable tool in pest management. Current distribution methods typically blow the mites over the crops, which result in uneven application…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Morse, Justin
  • Licensing Officer: Flammang, Ann Marie

Use of 3D printing for personal optimized nasal drug delivery
TS-038896 — Nasal sinusitis is one of the most common medical conditions in the US, affecting an estimated 12% of individuals, or some 29.4 million people (National Health Interview Survey 2015, CDC).Topical sinus irrigations (e.g. neti-pot, irrigation squeeze bottles) play an integral role in the management …
  • College: College of Medicine (COM)
  • Inventors: Zhao, Kai
  • Licensing Officer: Norris, Francis "Frank"

Dietary Carotenoid Assessment Tool (DCAT).
TS-038892 — A screening tool for rapid estimation of dietary carotenoid intake
The Need Diet is a major variable that contributes to human health and disease risk. Decades of scientific research suggest that dietary patterns rich in a variety of fruit and vegetables can reduce the risk of cancer through numerous mechanisms, however accurate dietary assessment remains challeng…
  • College: College of Medicine (COM)
  • Inventors: Clinton, Steven; Grainger, Elizabeth; Schmitz, Ashley; Simpson, Christina "Christi"; Thomas-Ahner, Jennifer
  • Licensing Officer: Flammang, Ann Marie

Method for predicting statin response: combination of two CYP7A1 variants
TS-038888 — A model to predict CYP7A1 activity and individual response to statins.
Cholesterol 7α-hydroxylase (CYP7A1) is an enzyme that catalyzes the first and the rate-limiting step in the biosynthesis of bile acid from cholesterol and serves as a main pathway for cholesterol removal from the body. CYP7A1 plays an important role in lipid metabolism and the development of…
  • College: College of Medicine (COM)
  • Inventors: Sadee, Wolfgang; Wang, Danxin
  • Licensing Officer: Norris, Francis "Frank"

Treatment of Multiple Sclerosis with small molecule IL-6/STAT3 inhibitors
TS-038701 — Small-molecule prodrugs that target IL-6/STAT3 signaling pathways can be used for treating patients with multiple sclerosis.
Multiple Sclerosis (MS), an unpredictable and disabling autoimmune disease affecting the central nervous system, is the leading cause of non-traumatic neurological disability in young adults. With no cure or efficacious therapies, most patients suffer from the effects of MS the remainder of their …
  • College: College of Medicine (COM)
  • Inventors: Yang, Yuhong; Li, Chenglong; Racke, Michael
  • Licensing Officer: Rumpal, Nidhi

Identification of a novel exercise-induced compound in breast milk that improves metabolic health of offspring.
TS-038700 — A novel exercise-induced compound in breast milk that improves metabolic health of offspring.
Type 2 diabetes is a complex disease that arises from a combination of environmental and genetic factors. Recent projections suggest that the prevalence of type 2 diabetes will increase to 25% of the U.S. population by 2050. While the incidence of the disease is rising, there is strong epidemiolog…
  • College: College of Medicine (COM)
  • Inventors: Stanford, Kristin; Bode, Lars
  • Licensing Officer: Flammang, Ann Marie

Iron Oxide Composites with Low Concentration of Aliovalent Dopants As Oxygen Carrier Materials for Sustainable Redox Combustion and Gasification Reactions in Chemical Looping Reactor Systems
TS-038513 — Addition of low concentration aliovalent transition metal dopants substantially improves particle performance in chemical loopiong systems
Cyclic systems are required for energy conversion systems. In the clean energy industry, chemical looping offers promise for carbon dioxide capture from fossil energy. Transition metal oxides such as iron oxide, nickel oxide, and copper oxide have been singled out as the desired active oxygen carr…
  • College: College of Engineering (COE)
  • Inventors: Fan, Liang-Shih; Cheng, Zhuo; Chung, Cheng; Guo, Mengqing "MENGQING"; Qin, Lang
  • Licensing Officer: Norris, Francis "Frank"

Development of a microRNA signature predicting local recurrence and overall survival after surgical resection for patients with pancreatic adenocarcinoma.
TS-038461 — A molecular tool for predicting risk of local and regional recurrence of pancreatic adenocarcinoma.
The median survival for patients with pancreatic adenocarcinoma is less than 4 months without treatment, although quick and effective treatments can increase this to 8 months. The five year survival rate is equally dismal at 8% and the disease is the fourth leading cause of cancer deaths in the Un…
  • College: College of Medicine (COM)
  • Inventors: Williams, Terence; Hite, Amy; Wald, Patrick
  • Licensing Officer: Rumpal, Nidhi

Blue & green colorants derived from naturally sourced delphinidin based anthocyanins
TS-038387 — A healthier, natural alternative to artificial blue and green food product colorants.
Color is a key attribute affecting the overall quality and flavor perception of foods and is critical to the product’s overall acceptance. Due to health concerns (such as allergies and possible carcinogenesis), consumer demand for natural products, and regulatory restrictions, the use of art…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Sigurdson, Gregory; Giusti, M. Monica "Monica"
  • Licensing Officer: Flammang, Ann Marie

OSU Canaan Fir; Abies balsamea var. phanerolepis; fir tree
TS-038235 — Relatively frost resistant Canaan fir tree.
Canaan fir (Abies balsamea var phanerolepis) tree variety with a provenance of Canaan Valley, West Virginia. James Brown (Ohio State University, School of Environment and Natural Resources) sorted out the five natural seed sources (provenances) of this tree. The provenances are all found in West Vir…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Brown, James
  • Licensing Officer: Dahlman, Jason "Jay"

OH04-264-58; Triticum Aestivum; Winter Wheat
TS-038234 — OH04-264-58 is a soft wheat with very strong gluten and stability over a variety of environments.
OH04-264-58 is a soft wheat with very strong gluten developed at The Ohio State University's Ohio Agricultural Research and Development Center. Current analyses indicate that the gluten strength of OH04-264-58 is similar to that of Pioneer 25R26 and shows stability in multiple environments. Its …
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Sneller, Clay
  • Licensing Officer: Dahlman, Jason "Jay"

OH7530; Solanum lycopersicum; tomato
TS-038132 — A new breed of tomatoes.
OH7530 was coded as F02-7530 in September 2002. OH7530 is derived from SG01-3008 a family with coupling-phase recombination for the Pto gene and the Rx-3 locus conferring resistance to Pseudomonas syringae pv. tomato and Xanthomonas euvesicatoria race T1, respectively, and described (Yang and Franci…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Francis, David; Aldrich, Troy
  • Licensing Officer: Dahlman, Jason "Jay"

OH2041; Solanum lycopersicum; Tomato
TS-038128 — A new breed of tomatoes.
This breed of tomato, called OH2041, was derived from F02-7060, an F1 between 01-BR-7087 and 01-BR-7069 (single plant selections from an IBC population). The seeds were saved, and then evaluated in 2004. The IBC population is described to have a resistance to bacterial spot race T4, and was characte…
  • College: College of Food, Agricultural, and Environmental Sciences (CFAES)
  • Inventors: Francis, David; Aldrich, Troy
  • Licensing Officer: Dahlman, Jason "Jay"

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