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High-Throughput Perfusion Platform for Standard Multi-Well Assays
TS-075845 — Drug discovery, biologics development, cell therapy research, and advanced in vitro testing all rely on large numbers of cell-based experiments. While continuous perfusion can improve biological relevance by maintaining nutrient availability, removing waste products, and better mimicking physiolog…
  • College: College of Engineering (COE)
  • Inventors: Agarwal, Shashwat; Jones, Travis; Song, Jonathan "Jon"
  • Licensing Officer: Ashouripashaki, Mandana

ElectroTag Diagnostics
TS-074316 — Pre‑Launch Start‑Up Opportunity: Seeking Business Leads ElectroTag is a multiplex diagnostics platform that enables simultaneous measurement of multiple disease‑associated proteins from a small patient sample. The system replaces conventional color‑based labels with mass‑encoded peptide tags that are read by mass spectrometry, delivering higher analytical specificity and a clear path to expanding from small to large biomarker panels while maintaining streamlined workflows.
Technology Overview Clinical and research laboratories are increasingly adopting multi‑marker panels to improve diagnosis, guide therapy selection, and monitor treatment response. Traditional formats such as ELISA plates and lateral flow strips rely on optical or enzymatic signals, which begin to…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Badu-Tawiah, Abraham; Seth, Ayesha; Zerrudo, Stephanee
  • Licensing Officer: Panic, Ana

NucNano: Predictive Drug Screening Platform
TS-071946 — Mechanistic drug screening technology to improve preclinical decision-making and reduce late-stage development risk.
Technology Summary NucNano is an emerging drug screening platform from The Ohio State University designed to help pharmaceutical and biotechnology companies identify more promising therapeutic candidates earlier in development. By moving beyond conventional assays that primarily measure bindin…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Poirier, Michael; Bonin, Kalven; Bundschuh, Ralf; Castro, Carlos
  • Licensing Officer: Panic, Ana

Instant Diagnostics, Anywhere
TS-070543 — A Handheld Diagnostics Platform for Point of Care Rapid Diagnostics
The diagnostics market faces pressure for faster and more reliable solutions that can access even the most remote of locations due to global health challenges. Existing diagnostic technologies require health care providers to choose between cost and diagnostic accuracy. Scalable multiplex biomarke…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Badu-Tawiah, Abraham; Seth, Ayesha; Zerrudo, Stephanee
  • Licensing Officer: Panic, Ana

Magnetic Nanoparticles for Cancer Cell Classification
TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Schultz, Zachary; Rist, David; Skardal, Aleksander; Venere, Monica
  • Licensing Officer: Panic, Ana

Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
  • College: College of Arts and Sciences (ASC)
  • Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
  • Licensing Officer: Dahlman, Jason "Jay"

Fluorescent probes for intracellular RNA tracking
TS-062554 — The Need: Intracellular RNA fluorescence labeling is a crucial technique for studying cellular processes and understanding gene expression. However, the conventional MS2 labeling method using protein fusion labels can have drawbacks, such as increased mass, potential steric accessibility issues, and…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Bong, Dennis; Liang, Yufeng
  • Licensing Officer: Panic, Ana

Rapid Viral Quantification with Target Gene Detection
TS-062346 — The Need The ability to rapidly identify and determine virus titer is of utmost importance in numerous biomedical applications, ranging from gene editing to pharmaceutical and vaccine development. Current methods for characterizing viruses and determining viral titer, such as ELISA, PCR, and cell c…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Schultz, Zachary; Morder, Courtney
  • Licensing Officer: Dahlman, Jason "Jay"

Ion Carpet-Based Surface-Induced Dissociation Device
TS-062342 — The Need In the field of mass spectrometry (MS), the study of proteins and protein complexes in their native form, known as native MS, has become crucial in understanding their structure and function. However, the current collision-induced dissociation (CID) technique used in tandem MS experiments …
  • College: College of Arts and Sciences (ASC)
  • Inventors: Wysocki, Vicki; Gilbert, Joshua; Stiving, Alyssa
  • Licensing Officer: Dahlman, Jason "Jay"

Paper-based Dried Blood Spheroids for Stabilization of Labile Organic Compounds Stored in Ambient Air
TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.
Dried blood spots on paper substrates offer a facile sample collection, storage, and transportation approach for biofluids. However, variable diffusion, volcanic effects, analyte instability, and difficulty in recovering samples from paper plague this method, lowering confidence in analyte quantif…
  • College: College of Arts and Sciences (ASC)
  • Inventors: Badu-Tawiah, Abraham; Damon, Deidre
  • Licensing Officer: Panic, Ana

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