TS-065455 — The Need: In modern biotechnology and biomedical research, there is an escalating demand for efficient tools that can accurately detect and analyze specific RNA sequences. The ability to precisely target and identify RNA molecules, particularly U-rich sequences, is crucial for various applications s…

TS-064577 — Glioblastoma (GBM) is the most common malignant brain tumor accounting for 47.7% of all brain cancers. Unfortunately, treatments are limited, and survival is poor, with approximately only 40% living past the first-year post-diagnosis and 17% in the second year. The Need Developing drugs for cance…

TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …

TS-062554 — The Need: Intracellular RNA fluorescence labeling is a crucial technique for studying cellular processes and understanding gene expression. However, the conventional MS2 labeling method using protein fusion labels can have drawbacks, such as increased mass, potential steric accessibility issues, and…

TS-062346 — The ability to rapidly identify and determine virus titer is of utmost importance in numerous biomedical applications, ranging from gene editing to pharmaceutical and vaccine development. In the context of lentiviruses, which are widely used for cell reprogramming in immunotherapies, knowing the e…

TS-062342 — The Need In the field of mass spectrometry (MS), the study of proteins and protein complexes in their native form, known as native MS, has become crucial in understanding their structure and function. However, the current collision-induced dissociation (CID) technique used in tandem MS experiments …

TS-062260 — The Need: Efficient and accurate diagnosis of maize lethal necrosis (MLN)-causing viruses is essential for MLN surveillance programs and testing seed for zero tolerance of Maize chlorotic mottle virus (MCMV) in seed lots. To effectively manage MLN in both farmers' fields and commercial seed fie…

TS-038604 — Apparatus and methods to form three-dimensional dried blood spheroids on hydrophobic paper substrates.

TS-037631 — Polymethylmethacrylate (PMMA) is a useful material for development of assays, biochips, and other biological materials. However, PMMA makes for a difficult substrate because of complexities with respect to adhesion. This technology presents two new methods for enhanced protein binding onto PMMA.

TS-014978 — A more accurate, cost efficient and faster method to one of the most widely used diagnostic tests in the world.