RAFT Agents for Controlled Radical Polymerization of Biofunctionalized Polymeric Materials
TS-068081 — These RAFT agents enable synthesis
of novel polymer materials with enhanced biocompatibility and tailored functionality, suited for a wide range
of biomedical applications.
Background
The growing demand for biofunctionalized polymer materials in fields such as drug delivery and diagnostics requires precise control over polymer properties. However, current reagents for Reversible Addition Fragmentation chain Transfer (RAFT) polymerization struggle with achieving the ne…
- College: College
of
Arts
&
Sciences
- Inventors: Kulkarni, Anuja; Watkins, Davita
- Licensing Officer: Panic, Ana
Co-Axial Contained Electrospray Ionization Platform for Mass Spectrometry
TS-067158 — The Need
Mass spectrometry (MS) is used across a wide range of applications for detection of various chemical analytes such as drug metabolites, pesticides, food adulterants, and natural product extracts. Recent developments have transformed MS into an all-purpose technique for in-situ and real-tim…
- College: College
of
Arts
&
Sciences
- Inventors: Badu-Tawiah, Abraham; Burris, Benjamin "Ben"; Grooms, Alex; Heiss, Derik; Kulyk, Dmytro
- Licensing Officer: Panic, Ana
Revolutionizing Hydrogen Production and CO2 Capture for a Sustainable Future
TS-065143 — The Need:
In the face of pressing environmental concerns and the imperative for sustainable energy solutions, there arises a critical commercial need for systems and methods that can efficiently produce hydrogen (H2) while simultaneously capturing and converting carbon dioxide (CO2) emissions. Trad…
- College: College
of
Arts
&
Sciences
- Inventors: Baker, Lawrence "Robert"
- Licensing Officer: Panic, Ana
Revolutionizing Pharmaceutical Synthesis: Advancements in Metal-Catalyzed Coupling Technology
TS-064824 — The Need
In the pharmaceutical industry, the synthesis of complex organic substrates is crucial for the development of life-saving medications. However, traditional metal-catalyzed coupling reactions often face significant challenges when applied to these complex substrates, leading to high failure…
- College: College
of
Arts
&
Sciences
- Inventors: Sevov, Christo; Dinh, Long; Hamby, Taylor; Starbuck, Hunter
- Licensing Officer: Panic, Ana
Method and device for determining virus titer by surface enhanced Raman scattering
TS-062346 —
The ability to rapidly identify and determine virus titer is of utmost importance in numerous biomedical applications, ranging from gene editing to pharmaceutical and vaccine development. In the context of lentiviruses, which are widely used for cell reprogramming in immunotherapies, knowing the e…
- College: College
of
Arts
&
Sciences
- Inventors: Schultz, Zachary; Morder, Courtney
- Licensing Officer: Dahlman, Jason "Jay"
Dual ligand systems for cross-coupling of challenging C(sp2) and C(sp3) electrophiles.
TS-059018 — An unusual series
of ligand exchange reactions establishes a dualcatalyst system for electroreductive alkyl-aryl cross-electrophile couplings
of previously incompatible substrate combinations.
Cross-electrophile coupling (XEC) reactions of aryl and alkyl electrophiles are desirable methodologies for C–C bond formation but are limited to specific substrate classes. Couplings of widely-available electrophiles such as aryl chlorides or triflates are currently unknown with any alkyl b…
- College: College
of
Arts
&
Sciences
- Inventors: Sevov, Christo; Hamby, Taylor
- Licensing Officer: Panic, Ana
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-058577 — Novel, transition metal-free catalysts capable
of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College
of
Arts
&
Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Panic, Ana
Transition Metal Free Alkyne Hydrogenation and Semihydrogenation Catalysts
TS-048726 — Novel, transition metal-free catalysts capable
of alkyne hydrogenation and semihydrogenation under modest conditions.
The Need
Numerous industrial processes require alkyne semihydrogenation or hydrogenation reactions. For example, hydrogenation is necessary for the industrial-scale synthesis vitamin A, the creation of high molecular weight polymers, and the processing of petroleum into functionally useful derivati…
- College: College
of
Arts
&
Sciences
- Inventors: Goldberger, Joshua; Hodge, Kelsey
- Licensing Officer: Panic, Ana
Development of a Single Component Methacrylate Adhesive Formulation
TS-042066 — A novel hybrid adhesive that combines the non-toxic, high strength properties
of methacrylate adhesives with the bonding characteristics
of polyurethanes
Despite the utility of methacrylate adhesive chemistry, applications have been limited to industrial and biomedical use cases. This is due to the curing mechanism, which is initiated by either heat, light or a two-component redox system. This invention describes two strategies to create a single-c…
- College: College
of
Arts
&
Sciences
- Inventors: Parquette, Jonathan; Schricker, Scott
- Licensing Officer: Dahlman, Jason "Jay"
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