Label-Free Raman Imaging for Early Detection of Disease Remodeling
TS-076401 —
Many progressive diseases, including cardiac, neurological, and other chronic disorders, begin with subtle molecular and cellular changes long before conventional clinical signs become detectable. Current diagnostic approaches generally identify disease only after significant tissue remodeling or …
- College: College
of
Engineering
(COE)
- Inventors: Veeraraghavan, Rengasayee; Ammon, Madison; Radwanski, Przemyslaw; Selimi, Zoja
- Licensing Officer: Ashouripashaki, Mandana
AI-Enabled Quantitative Assessment of External Heart Pump Performance
TS-075868 —
Clinicians managing pediatric patients supported by a ventricular assist device must routinely assess pump performance by visually estimating membrane fill and ejection during pump cycles. These evaluations are critical for patient management but are inherently subjective, time-consuming, and pron…
- College: College
of
Engineering
(COE)
- Inventors: Eichaker, Lauren; Fabian, Benjamin; Florence, Megan; Jain, Amara; Juarez, Alejandro; Nandi, Deipanjan; Robinson, Tavi; Sharma, Meghna
- Licensing Officer: Sharick, Joe
Noninvasive Ultrasound Platform for 3D Posterior Eye Morphometry
TS-074779 —
Myopia is rapidly increasing worldwide and is now recognized as a leading cause of irreversible vision impairment due to associated complications such as retinal degeneration, glaucoma, and structural eye changes. Despite this growing burden, clinicians lack practical tools to assess structural ch…
- College: College
of
Engineering
(COE)
- Inventors: Liu, Jun; Chen, Zihao; Zheng, He
- Licensing Officer: Randhawa, Davinder
Method to Determine Tremor Frequency from Deep Brain Stimulation Signals
TS-070304 — The Need
Current clinical methods for assessing tremor severity in patients with Parkinson’s disease and other movement disorders rely heavily on subjective, qualitative observations, such as evaluating hand-drawn spirals or observing motor tasks. These approaches lack precision, are difficult…
- College: College
of
Engineering
(COE)
- Inventors: Khan, Furrukh; Dalm, Brian; Novikov, David; Thomas, Evan; Zhao, Jessie
- Licensing Officer: Randhawa, Davinder
Motion-Guided Deep Image Prior (M-DIP) for Dynamic Image Reconstruction in Cardiovascular MRI
TS-069527 — The Need
Cardiovascular MRI (CMR) data acquisition is often time-consuming and relies on complex reconstruction methods that do not fully exploit the spatial and temporal structure of CMR data. There is a need for a more efficient, unsupervised approach that can accelerate CMR imaging while maintai…
- College: College
of
Engineering
(COE)
- Inventors: Ahmad, Rizwan; Chen, Chong; Sultan, Muhammad
- Licensing Officer: Randhawa, Davinder
High-K Dielectric barriers to suppress internal photoemission photocurrents
TS-063471 —
In an increasingly digital world, the demand for efficient and reliable photodetectors is paramount. These devices are critical for a variety of applications, from medical imaging to defense systems. However, traditional photodetectors often struggle with low UV-visible rejection, limiting their e…
- College: College
of
Engineering
(COE)
- Inventors: Rajan, Siddharth; McGlone, Joseph "Joe"; Wriedt, Nathan
- Licensing Officer: Ashouripashaki, Mandana
A Regularized Conditional GAN for Posterior Sampling in Inverse Problems
TS-063238 — A novel regularization technique applicable for medical imaging applications that leverages conditional generative adversarial networks (cGANs) to generate reconstructed images in significantly shorter timeframes.
The Need
Several techniques are used for image reconstruction in the medical aren…
- College: College
of
Engineering
(COE)
- Inventors: Bendel, Matthew; Ahmad, Rizwan; Schniter, Philip "Phil"
- Licensing Officer: Hampton, Andrew
Tracking Breast Tissue Tumor Cavity after Lumpectomy
TS-062715 — Radiopaque biodegradable polymer for the tracking
of the breast tissue tumor cavity after lumpectomy and other radiation therapy applications
Approximately 40% of women diagnosed with breast cancer undergo a lumpectomy procedure. Approximately 170,000 lumpectomies are performed each year in the United States. Typically, this operation is followed by radiation therapy to ensure there are no remaining cancerous cells in the region. It is …
- College: College
of
Engineering
(COE)
- Inventors: Metzler, Sandra; Elisha, Deji; Evans, Izzy; Fedro, Joseph; Krakovsky, Mia; Sherry, Adam; Skoracki, Roman
- Licensing Officer: Sharick, Joe
Methods to measure biophysical attributes of the posterior eye
TS-062505 — The Need
Glaucoma and myopia are significant causes of vision loss worldwide, affecting millions of people and imposing a substantial socioeconomical burden. Effective vision care strategies are urgently needed to reduce blindness caused by these conditions and mitigate their associated risks. In v…
- College: College
of
Engineering
(COE)
- Inventors: Liu, Jun; Kwok, Sunny
- Licensing Officer: Randhawa, Davinder
Methods for quantifying the biomechanical attributes of the cornea and the anterior sclera
TS-062497 — The Need:
The field of ophthalmology requires advanced diagnostic tools to effectively diagnose, prevent, and treat various eye conditions. While ultrasound imaging is well-known in fields like pregnancy check-ups and vascular imaging, its potential in ophthalmology remains largely untapped. There …
- College: College
of
Engineering
(COE)
- Inventors: Liu, Jun; Kwok, Sunny
- Licensing Officer: Randhawa, Davinder
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