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A modified intein for temperature sensitive applications
TS-063697 — Controlled Protein Release Over a Broad Range of Temperatures
The Need: In the biotechnology field, the demand for efficient protein purification methods and innovative drug delivery solutions is ever-growing. Researchers and companies require technologies that can streamline the purification process, ensuring high yields and purity, while offering versatile …
  • College: College of Engineering (COE)
  • Inventors: Wood, David; Coolbaugh, Michael; Stimple, Samuel "Sam"; Yuan, Hongyu
  • Licensing Officer: Dahlman, Jason "Jay"

Advanced AAV Gene Therapy Characterization Technique
TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Cleary, Sean; Du, Chen
  • Licensing Officer: Dahlman, Jason "Jay"

Functional "fingerloop" DNA antisense motifs for nucleic acid targeting and detection technologies
TS-062547 — The Need: The field of molecular biology and genetic engineering faces challenges in achieving precise and accurate detection and amplification of target nucleic acid sequences. Traditional hybridization technologies suffer from the issue of mismatched targets, leading to reduced specificity and rel…
  • College: College of Arts & Sciences
  • Inventors: Lease, Richard
  • Licensing Officer: Dahlman, Jason "Jay"

Anaplasma Platys Diagnostics
TS-062349 — The Need In the veterinary field, there is a crucial need for accurate and specific diagnostic tests to identify and distinguish between Anaplasma platys (Apl) and other related pathogens like Anaplasma phagocytophilum (Aph). Current diagnostic methods lack specificity, leading to challenges in dif…
  • College: College of Veterinary Medicine
  • Inventors: Rikihisa, Yasuko
  • Licensing Officer: Dahlman, Jason "Jay"

Rapid Viral Quantification with Target Gene Detection
TS-062346 — The Need The ability to rapidly identify and determine virus titer is of utmost importance in numerous biomedical applications, ranging from gene editing to pharmaceutical and vaccine development. Current methods for characterizing viruses and determining viral titer, such as ELISA, PCR, and cell c…
  • College: College of Arts & Sciences
  • Inventors: Schultz, Zachary; Morder, Courtney
  • Licensing Officer: Dahlman, Jason "Jay"

Ion Carpet-Based Surface-Induced Dissociation Device
TS-062342 — The Need In the field of mass spectrometry (MS), the study of proteins and protein complexes in their native form, known as native MS, has become crucial in understanding their structure and function. However, the current collision-induced dissociation (CID) technique used in tandem MS experiments …
  • College: College of Arts & Sciences
  • Inventors: Wysocki, Vicki; Gilbert, Joshua; Stiving, Alyssa
  • Licensing Officer: Dahlman, Jason "Jay"

Method for controlling multiple heterogenous magnetic bacteria at a solid-liquid interface using uniform magnetic fields
TS-053222 — Manipulatable miniaturized robots have a variety of applications in biomedical sciences, specifically microrobots capable of navigating in vivo blood vessels have the potential to revolutionize non-invasive surgery and targeted drug delivery for cancer and other disease treatment. Drug discovery c…
  • College: College of Arts & Sciences
  • Inventors: Wijesinghe, Hiran
  • Licensing Officer: Dahlman, Jason "Jay"

Canine Lymphoma Cell Line
TS-015190 — A novel canine lymphoma cell line developed from the malignant pleural effusion of a dog with peripheral T-cell lymphoma.
Lymphoma is the most common life-threatening cancer of dogs, accounting for up to 24% of all malignancies and over 80% of all hematopoietic cancers. Spontaneously occurring lymphoma in the dog has many of the same histopathological, molecular, and clinical features as non-Hodgkin’s lymphoma …
  • College: College of Veterinary Medicine
  • Inventors: Kisseberth, William
  • Licensing Officer: Dahlman, Jason "Jay"

Rapid-Reset Targets for High-Power Lasers
TS-014771 — A variable thickness liquid film target is generated at repetition rates in excess of 10 Hz for laser interaction applications
The Need High-powered lasers that generate extreme temperatures and pressures can be fired multiple times per second in laser-matter experiments. However, while lasers can fire many times per second, setting up their targets for experiments or neutron generation is substantially slower. These targe…
  • College: College of Arts & Sciences
  • Inventors: Poole, Patrick; Andereck, Claude; Schumacher, Douglass
  • Licensing Officer: Dahlman, Jason "Jay"

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