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3D Object-based Segmentation-based Quantification of Spatial Protein Organization (OBS3D)
TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.
Colocalization analysis is the current standard technique for assessing spatial association of co‐labeled proteins in cells using multicolor immunofluorescence images. However, these tools are limited because multiple antigens nearby exhibit overlapping staining, which leads to inaccurate analys…
  • College: College of Engineering (COE)
  • Inventors: Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

Grass Surrogate
TS-062844 — Road departure is a serious threat to vehicle safety and can result in fatal accidents. To prevent road departure, some vehicles are equipped with a road departure mitigation system that can detect when a vehicle is about to leave the road and take corrective actions. However, there is a need for …
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih
  • Licensing Officer: Zinn, Ryan

Surrogates for Concrete Dividers
TS-062834 — Road departure can be extremely dangerous for vehicles. Some vehicles are equipped with road departure mitigation systems to prevent this from happening. However, testing these systems can be difficult and costly, as it involves crashing vehicles into roadside objects. The concrete divider surr…
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih; Chen, Yaobin; Chien, Stanley; Lin, Jun; Sherony, Rini; Yi, Qiang
  • Licensing Officer: Zinn, Ryan

Surrogates for Metal Guardrails
TS-062797
Road departures remain a significant source of traffic accidents. Tools for limiting road departures are needed to reduce accidents and improve safe driving conditions. The Ohio State University researcher Dr. Chi-Chih Chen, along with a team of researchers, has developed a novel metal guardrai…
  • College: College of Engineering (COE)
  • Inventors: Chen, Chi-Chih; Chen, Yaobin; Chien, Stanley; Lin, Jun; Sherony, Rini
  • Licensing Officer: Zinn, Ryan

Oxygen Sensing Nanofibers
TS-014967 — Nanofibers designed to quantify the oxygen content of a local environment for cell cultures and tissue-based applications such as a wearable technology wirelessly integrated into an electronic device used to estimate the efficiency of an individual's oxygen consumption.
Measurements of growth and activity of living cells are advantageous in a wide array of applications. Such measurements can be used to track tissue regeneration, phenotypic change, localized hypoxia, the testing and development of antibiotics and much more (Maria Strianese et al., Scott Lynn et al…
  • College: College of Engineering (COE)
  • Inventors: Lannutti, John; Xue, Ruipeng
  • Licensing Officer: Zinn, Ryan

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