TS-063911 — Porosity formation during the solidification of aluminum-based alloys, induced by hydrogen gas and alloy shrinkage, presents a significant challenge for industries relying on high-performance solidification products such as castings, welds, and additively manufactured components. This issue advers…

TS-062843 — This MIMO-PLC architecture is the first scalable MIMO architecture on a single power line. It improves the throughput for power line communication (PLC) by utilizing the existing power delivery infrastructure and allows for high data rates in rural areas.

TS-062834 — Road departure can be extremely dangerous for vehicles. Some vehicles are equipped with road departure mitigation systems to prevent this from happening. However, testing these systems can be difficult and costly, as it involves crashing vehicles into roadside objects. The concrete divider surr…

TS-062797 —

TS-062690 — Novel niclosamide analogues with improved bioavailability and mitigated dose-limiting toxicities.

TS-062685 — Cancer is a leading cause of death worldwide, accounting for nearly 10 million deaths in 2020, or nearly one in six deaths. The most common cancers are breast, lung, colon and rectum and prostate cancers. The Need Current cancer treatments mainly rely on chemotherapy, radiation, surgery and bon…

TS-062608 — Gene therapy is an emerging technology that replaces a faulty gene or adds a new gene to cure disease or improve your body's ability to fight infection. These next-generation treatments hold promise for treating various genetic and chronic conditions, including but not limited to cancer, cystic …

TS-062605 — The Need: Castration-resistant prostate cancer (CRPC) poses a significant challenge in oncology, with existing therapies often leading to resistance and disease progression. Key drivers of resistance include the androgen receptor (AR) and aldo-keto reductase family 1 member C3 (AKR1C3). Novel treat…

TS-062601 — Only a small fraction of the radio frequency (RF) energy transmitted by smartphones and other wireless devices is used to communicate with a wireless access point. It would be useful to collect or harvest the unused RF signals in order to convert them to direct current (DC) power and supplement th…

TS-062596 — Conventional rectifying circuit designs convert alternating-current (AC) signals into direct-current (DC) signals via the used of diodes. Low-barrier Schottky diodes are used in low AC power cases such as with ambient radio frequency (RF) signals. Ideally, each diode is only turned on during the p…

TS-062218 — The Need: Flavor Modulating Compounds for Healthier Food and Beverages In a world where taste preferences drive consumer choices, the demand for nutritious and palatable food and beverages remains at an all-time high. However, many nutrient-rich foods, such as vegetables and whole grains, often possess bitter flavors that can be unappealing to consumers. To make these foods more enjoyable and mask the bitterness, manufacturers frequently resort to excessive amounts of unhealthy additives like fats, sugars, and salts. The result is a trade-off between taste and health, leaving consumers seeking a solution that provides both flavor satisfaction and nutritional benefits. The Technology: Innovative Flavor Modulating Compounds Our technology offers a groundbreaking solution to the challenge of balancing taste and health in food and beverages. Developed as additives for the food industry, our flavor modulating compounds effectively block or modulate bitter flavors, enabling significant reductions in the need for added sugars and salts. By utilizing these compounds, manufacturers can maintain the palatability of their products without compromising on nutritional value. Commercial Applications: Unlocking the Potential The versatility of our flavor modulating compounds opens up numerous commercial applications across various food and beverage categories: Healthy Snacks: Create nutritious and appealing snacks using bitter-rich ingredients, like vegetable chips and whole grain crackers, while minimizing the need for excessive unhealthy additives. Low-Sugar Beverages: Develop refreshing drinks with reduced sugar content, ensuring that consumers enjoy a satisfying taste experience without the guilt of excess sugar consumption. Nutrient-Enhanced Foods: Enhance the flavor profile of nutrient-rich foods, such as salads and soups, to make them more enjoyable, encouraging healthier eating habits. Confectionery: Improve the taste of health-focused sweets and candies, enabling confectionery brands to cater to health-conscious consumers. Ready-to-Eat Meals: Incorporate flavor modulating compounds into pre-packaged meals, enhancing taste while adhering to nutritional guidelines. Benefits/Advantages: Elevating Consumer Experience and Market Appeal Our flavor modulating compounds offer an array of advantages for food and beverage manufacturers, making them a valuable addition to any product development strategy: Healthier Product Profiles: Enable the creation of low-sugar, low-salt products, supporting consumer health and well-being. Uncompromised Taste: Maintain delicious flavor profiles while reducing or eliminating unhealthy additives, satisfying consumer cravings. Market Differentiation: Stand out in a crowded market by offering healthier alternatives without sacrificing taste. Health-Conscious Appeal: Attract health-conscious consumers seeking better-for-you options, expanding your target audience. Regulatory Compliance: Align with evolving nutritional guidelines and regulations, positioning your products for long-term success. In conclusion, our flavor modulating compounds revolutionize the way food and beverages are formulated. By addressing the commercial need for healthier options without compromising on taste, our technology unlocks vast opportunities for manufacturers to create products that appeal to consumers' palates and prioritize their well-being. Join us on this journey towards a future of delightful, nutritious, and flavorful food and drink experiences.

TS-062211 — The Need: Addressing the Limitations of Current Flu Vaccines Influenza epidemics and pandemics present significant challenges to public health and global economies. Existing flu vaccines are strain-specific, providing limited cross-protective immunity and often lack long-term effectiveness. Additio…

TS-061849 — The Rare Earth Element Trap-Extract-Precipitate (REE-TEP) process is a cost-effective and environmentally benign approach to recover rare earth elements (REEs) from acidic waste streams. It involves beneficial reuse of readily available industrial by-products and a naturally occurring organic ligand resulting in REE concentrate that can be commercially processed to produce rare earth oxides (REOs).

TS-060092 — AI methods and systems for predicting reactants and their synthesis paths to support drug design and chemical synthesis.

TS-058084 — A rabbit model has been created for Duchenne Muscular Dystrophy (DMD) that more closely resembles the effects experienced in humans while being more cost effective compared to larger animal models.

TS-054550 — Sensing gases with high specificity and sensitivity in complex environments ranging from combustion processes to breath sensing using miniaturized solid-state electrochemical sensors.

TS-049505 — An engineered base editor (iABE-NG) that uses an SpCas9 variant, a shortened adenine deaminase domain with eliminated RNA off-target activity, and an intein split for packaging into an adeno-associated virus (AAV), resulting in gene mutation correction.

TS-043725 — VHF Antenna with significant height reduction with capability to operate in a wideband

TS-039004 — Pericelle: a nanoparticle based perivascular drug delivery system to prevent stenosis and failure in vascular reconstruction surgeries.

TS-038701 — Small-molecule prodrugs that target IL-6/STAT3 signaling pathway.