Available Technologies
# of Displayed Technologies: 5 / 5
Applied Category Filter (Click To Remove): Life & Health Sciences
Methods for Measuring Contrast Sensitivity
TS-062308 — The Need:
Visual sensitivity testing plays a crucial role in assessing human vision and detecting potential visual impairments. However, traditional methods often lack the precision required to isolate specific frequency-specific channels in the visual system. There is a commercial need for a techn…
- College: College of Arts & Sciences
- Inventors: Lu, Zhong-Lin
- Licensing Officer: Dahlman, Jason "Jay"
Peptide-based therapeutic intervention for Cardiac Ryanopathies
TS-062097 — Novel polypeptides and polynucleotides targeting RyR2 to address dysregulated Ca2+ release.
The cardiac ryanodine receptor channel 2 (RyR2) is known as the Ca2+ release channel of the sarcoplasmic reticulum (SR), and is believed to be a good therapeutic target in a group of certain heart diseases, known as cardiac ryanopathies. A number of mutations in the RyR2 gene have been linked to a w…
- College: College of Medicine (COM)
- Inventors: Singh, Harpreet
- Licensing Officer: Schultz, Teri
Better Recognition of Exposure to Asthma Triggers in the Home Environment using Smartphones (BREATHES)
TS-041784 — A tool for simply and affordably assessing levels of certain household allergens and asthma triggers.
Asthma is one of the most common chronic conditions among children in the United States and a major cause of childhood disability. Despite advances in medical treatment, many children have poor asthma control that results in disruptions in school attendance, extracurricular activities, exercise, a…
- College: College of Engineering (COE)
- Inventors: Dannemiller, Karen; Gouma, Pelagia-Iren; Perzanowski, Matthew; Qin, Rongjun
- Licensing Officer: Ashouripashaki, Mandana
Antisense Oligonucleotide Development for Treatment of Spinal Muscular Atrophy
TS-037741 —
The SMN2 gene contains sequences that regulate the level of inclusion of SMN exon7 in SMN mRNA, and some of these act in a negative manner. Antisense oligonucleotides to block the negative regulating protein binding to these sites can increase inclusion of SMN exon 7 and thus, the amount of SMN being produced.
Spinal muscular atrophy (SMA) is an inherited disease affecting the central nervous system, peripheral nervous system, and skeletal muscle. It is present primarily in infants and children but can also develop in adults. About 10,000 to 25,000 children and adults are living with the disease in the …
- College: College of Medicine (COM)
- Inventors: Burghes, Arthur; McGovern, Vicki; Prior, Thomas
- Licensing Officer: He, Panqing
miR-3151 and BAALC as a Target for Drug Therapy
TS-014895 — Identified gene target for treatment of human acute leukemia, brain tumors and melanoma
Treatment failure is one of the leading causes of death in patients with human acute leukemia, yet the cause of treatment failure is still largely unknown. Overexpression of the RNA gene miR-3151 and its host gene, Brain and Acute Leukemia, Cytplasmic (BAALC), is a sign of an ineffective treatment…
- College: College of Medicine (COM)
- Inventors: de la Chapelle, Albert; Eisfeld, Ann-Kathrin; Tanner, Stephan
- Licensing Officer: Schworer, Adam
