# of Displayed Technologies: 3 / 3

Applied Category Filter (Click To Remove): Molecular Biology


3D Object-based Segmentation-based Quantification of Spatial Protein Organization (OBS3D)
TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.
Colocalization analysis is the current standard technique for assessing spatial association of co‐labeled proteins in cells using multicolor immunofluorescence images. However, these tools are limited because multiple antigens nearby exhibit overlapping staining, which leads to inaccurate analys…
  • College: College of Engineering (COE)
  • Inventors: Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

System for automated high-speed imaging and genetic manipulation of C. elegans on agar media
TS-065892 — The Need The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …
  • College: College of Engineering (COE)
  • Inventors: Fang-Yen, Christopher "Chris"; Alhalbi, Serge; Li, Zihao
  • Licensing Officer: Randhawa, Davinder

"Flexible biomarker biofluid cell array for 2D/3D mapping of biomarker concentration levels"
TS-062483 — Measurement/detection of analytes (e.g., biomarkers) in different environments (e.g., biofluids/organs) is typically performed using a biosensor. Available bio-integrated sensors do not provide the capability to map biomarker concentrations, require a power source to function, use a limited number of electrodes, and normally can only measure a specific type of biofluid but not others. The use of glutamate mapping technology (radioactive or fluorescent ligand bound to a glutamate receptor) has been evaluated and found to require bulky/expensive medical equipment, a power source for measurement, cannot be miniaturized or integrated into a bio tissue, and require patients to be stationary during measurement.
The Need To address concerns and limitations with current biomarker detection/ measurement technologies, an alternative, cost-effective, efficient biosensing system/device capable of 2D/3D mapping the concentrations of various biomarkers in different bio environments is required. The Technology …
  • College: College of Engineering (COE)
  • Inventors: Li, Jinghua; Liu, Tzu Li; Nithianandam, Prasad
  • Licensing Officer: Ashouripashaki, Mandana

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