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Novel Quantitative Method to Detect Mold Growth in Buildings
TS-066963 — The Need Exposure to mold in homes costs billions of dollars every year. Exposure is particularly harmful to the 8% of the United States population that suffers from asthma; a leading cause of disability in children. Currently, odor, visible mold growth, and dampness are the best indicators of mold…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Balasubrahmaniam, Neeraja; Bope, Ashleigh
  • Licensing Officer: Ashouripashaki, Mandana

Dust Analysis: A Novel Approach to Monitoring Viral Spread
TS-066962 — The Need Viral disease (such as influenza viruses and SARS-CoV-2) surveillance in high-risk settings faces several challenges, such as asymptomatic carriers, incomplete reporting, resource limitations, and delayed diagnosis of traditional swab test methods. These challenges could allow a virus to s…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Faith, Seth; Hull, Natalie; Nastasi, Nick; Renninger, Nicole
  • Licensing Officer: Ashouripashaki, Mandana

Smartphone Detection Kit for Airborne Formaldehyde and Allergens
TS-066960 — The Need Indoor air can be polluted by various sources, including building materials, furniture, cleaning products, and even people. Exposure to these resulting contaminants and allergens can lead to a variety of health problems, such as respiratory irritation, allergies, and even cancer. It is cur…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Parquette, Jonathan; Qin, Rongjun
  • Licensing Officer: Ashouripashaki, Mandana

Color Correction System for Accurate Colorimetric Smartphone Measurements
TS-066957 — The Need Colorimetric tests and remote image analysis are used in a wide range of industrial and medical applications. Digital image-based measurements made with smartphones are a promising platform to quantify colors at low cost, but suffer from inconsistency and errors caused by lens quality, sen…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Panescu, Jenny; Qin, Rongjun; Song, Shuang; Zhang, Guixiang
  • Licensing Officer: Ashouripashaki, Mandana

Unveiling the Nanoscale: Breakthrough Analytical Speed of Real-Time Super-Resolution Microscopy and Beyond
TS-066926 — This Ohio State University software innovation offers groundbreaking analytical speed and automation of Single-Molecule Localization Microscopy (SMLM) as well as analysis of 3D data and images extending beyond the field of microscopy. Our technology offers real-time spatial analysis in continuous and discrete space, enabling unprecedented speed and efficiency in data processing that translates into faster decision-making, high-throughput screening capabilities, and broad applicability beyond traditional microscopy.
Single-molecule localization microscopy (SMLM) describes a family of fast-evolving, powerful imaging techniques that dramatically improve spatial resolution over standard, diffraction-limited microscopy techniques and can image biological structures at the molecular scale. SMLM can now be performe…
  • College: College of Engineering (COE)
  • Inventors: Soltisz, Andrew; Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

Humanized SSTR2 mAb and ADC to target SSTR2+ tumors
TS-066912 — Targeted humanized mAbs and ADCs for cancer treatment
The Liu Lab Dr. Xiaoguang “Margaret” Liu applies her industry experience (Lonza, Merck, and Life Technologies) in cell line and process development towards her lab’s focus on targeted anti-cancer therapies including monoclonal antibodies, antibody-drug conjugates, and gene therapi…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xiaoguang "Margaret"; Zhou, Lufang
  • Licensing Officer: Schworer, Adam

Revolutionary Modular Nuclear Reactor Core for Space Exploration
TS-066252 — Rotating Fuel Core with Fuel Strip(s) ("ROFFUS") is an innovative modular nuclear reactor core designed to provide reliable and scalable power for advanced space missions.
Future space missions require dependable, high-output energy sources to support operations such as material processing, transportation, and thermal conditioning, particularly in challenging environments like the lunar poles where sunlight is scarce. This advanced nuclear reactor core features a…
  • College: College of Engineering (COE)
  • Inventors: Smidts, Carol; Aldemir, Tunc; Cao, Lei Raymond; Horack, John; Khafizov, Marat
  • Licensing Officer: Zinn, Ryan

BDAMPER: Advanced Application Software for Dynamic Analysis and Design of Friction Damper Structures
TS-066234 — In the realm of rotating machinery and structural engineering, the need to manage and mitigate vibrations is paramount. Excessive vibrations can lead to material fatigue, operational inefficiency, and catastrophic failures. Industries require a sophisticated, accurate, and versatile tool to design…
  • College: College of Engineering (COE)
  • Inventors: Menq, Chia-Hsiang; Yang, Been-Der
  • Licensing Officer: Zinn, Ryan

3D Object-based Segmentation-based Quantification of Spatial Protein Organization (OBS3D)
TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.
Colocalization analysis is the current standard technique for assessing spatial association of co‐labeled proteins in cells using multicolor immunofluorescence images. However, these tools are limited because multiple antigens nearby exhibit overlapping staining, which leads to inaccurate analys…
  • College: College of Engineering (COE)
  • Inventors: Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

Innovative Solutions for Cell Viability and Targeted Delivery
TS-066100 — Research tool to transfect cells ex vivo using electroporation through electrospun core-shell fibers for research applications
The Need: Conventional electroporation methods often result in low cell viability due to heat generation, especially when working with primary cells. These methods also face challenges with non-specific transport of molecules, high vector integration rates leading to mutagenesis, and inefficacy in …
  • College: College of Engineering (COE)
  • Inventors: Gallego Perez, Daniel; Das, Devleena; Duarte Sanmiguel, Silvia; Higuita Castro, Natalia
  • Licensing Officer: Schultz, Teri

A Cybersecurity Vulnerability Prioritization System Including Identifying "Super-Critical" Vulnerabilities, predicting "Dark Host" Vulnerabilities, and Addressing Economic Costs
TS-066063 — Our cybersecurity vulnerability maintenance system stands as a pillar of modern security strategy, transforming reactive security measures into a preemptive defense mechanism. This integration of technology and economics ensures that your most critical assets are protected efficiently and effectively, making it an invaluable tool for any organization serious about security.
In today’s hyper-connected world, the escalation in cyber threats poses significant risks to organizational data and systems. Vulnerabilities within network infrastructures can lead to massive security breaches, as demonstrated by incidents like the 2017 Equifax hack. Effective vulnerability…
  • College: College of Engineering (COE)
  • Inventors: Allen, Theodore; Liu, Enhao
  • Licensing Officer: Zinn, Ryan

SimulationAI -- AI-Enabled Software Solution for Physics-Based Simulations
TS-066058 — By adopting our AI-driven solution, engineering teams can achieve more in less time, push the boundaries of innovation, and significantly cut down costs, all while maintaining or increasing the reliability and accuracy of their structural and material analysis. This is not just an evolution in FEM technology—it's a revolution.
In an era where precision and efficiency drive the success of engineering projects, the finite element method (FEM) remains indispensable but is burdened by high operational and computational costs. These costs often lead to overlooked uncertainty factors, suboptimal designs, and significant finan…
  • College: College of Engineering (COE)
  • Inventors: Soghrati, Soheil; vemparala, Balavignesh; Yang, Ming
  • Licensing Officer: Zinn, Ryan

System for automated high-speed imaging and genetic manipulation of C. elegans on agar media
TS-065892 — The Need The microscopic worm C. elegans is a model animal studied in more than 1500 biological and medical research laboratories worldwide due to its genetic manipulability and optical transparency. In C. elegans research, the manual process of picking worms between plates presents a significant …
  • College: College of Engineering (COE)
  • Inventors: Fang-Yen, Christopher "Chris"; Alhalbi, Serge; Li, Zihao
  • Licensing Officer: Randhawa, Davinder

Novel Therapeutic Approach to Treating Painful Musculoskeletal Disorders
TS-065684 — Non-viral gene therapy for minimally invasively treating painful musculoskeletal disorders
Painful musculoskeletal disorders like intervertebral disc (IVD) degeneration associated with chronic low back pain (DBP) present a significant socio-economic burden worldwide. The Need Current treatments for painful musculoskeletal disorders offer only temporary relief or invasive surgical proce…
  • College: College of Engineering (COE)
  • Inventors: Walter, Devina; Gallego Perez, Daniel; Higuita Castro, Natalia; Khan, Safdar; Tang, Shirley "Shirley Nina"; Walter, Benjamin
  • Licensing Officer: Schultz, Teri

Sacrificial Layer to Facilitate Welding of Thin Foils
TS-065430 — Cost-effective method to prevent damaged electrodes when welding thin foils.
Manufacturing of automotive lithium-ion batteries and battery packs is attracting growing attention with the driving demands of electric vehicles. During battery assembly, multi-layers of metal films, functioning as anodes, cathodes, or bus-bars are welded together. Achieving satisfying weld quali…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xun; Kwon, Ho; Shah, Umair
  • Licensing Officer: Zinn, Ryan

Use of Cerium in Neutralizing Iron Impurity in Aluminum Alloys
TS-065429 — Iron is the main and most detrimental impurity in most industrial casting aluminum alloys. Iron content in aluminum alloys is limited, up to 0.1 weight% in some alloys.
Iron is a major impurity element in primary and secondary (scrap) aluminum alloys. It is difficult to remove during melting and casting. Controlling the formation of Al-Fe-based intermetallics via alloying is key to leveraging the mechanical properties of aluminum alloy products. The current struc…
  • College: College of Engineering (COE)
  • Inventors: Luo, Alan; Cinkilic, Emre; Moodispaw, Michael
  • Licensing Officer: Zinn, Ryan

Streamlined Die Design Approach for Friction Stir Extrusion
TS-065428 — The Ohio State University researchers led by Dr. Rajiv Shivpuri have developed a die design approach for friction stir extrusion that optimizes metal flow to improve production efficiencies.
Friction stir extrusion (FSE) is a variation of friction stir processing that enables the hot extrusion of metal profiles from billet or other precursor material without preheating. This process saves significant thermal energy over conventional metal extrusion processes and can impart favorable …
  • College: College of Engineering (COE)
  • Inventors: Shivpuri, Rajiv
  • Licensing Officer: Zinn, Ryan

Open Circuit Voltage Photodetector
TS-065426 — Photodetectors are devices that detect light and convert it into an electrical signal. They operate based on the photoelectric effect, in which photons (light particles) strike the semiconductor material, creating electron-hole pairs that lead to the flow of electrical current that can be measured.
Existing photodetectors are susceptible to various noise sources, such as thermal and electronic. The noise can degrade the signal-to-noise ratio and affect the accuracy of measurements, particularly in low-light conditions. This technology is an open-circuit voltage photodetector (OCVP) that…
  • College: College of Engineering (COE)
  • Inventors: Krishna, Sanjay; Fuller, Earl; Kazemi, Alireza; Khalil, Waleed; Ronningen, TJ; Smith, Dale "Shane"; Specht, Teressa; Tantawy, Ramy "Ramy"
  • Licensing Officer: Zinn, Ryan

Containment System for Heating and Off-Gassing
TS-065424 — Due to environmental concerns and the decreasing supply of fossil fuels, there is substantial demand for nuclear-based energy production. Nuclear energy now provides about 10% of the world's electricity from about 440 power reactors and is the second largest source of low-carbon power. In addition, over 50 smaller countries utilize nuclear energy in about 220 research-size reactors. These reactors are used to produce medical and industrial isotopes and several other purposes.
It is essential to meet the safeguard requirements in liquid-fueled molten salt reactors, fuel salt transportation, and fuel cycle processes and to develop effective methods for measuring and monitoring the mass of molten fuel salt or coolant salt. However, due to the complex and dynamic nature o…
  • College: College of Engineering (COE)
  • Inventors: Van Zile, Matthew; Cao, Lei Raymond; Kauffman, Andrew
  • Licensing Officer: Zinn, Ryan

Fluid Active Flow Control Enabled Variable Turbine Vane
TS-065423 — Turbine aircraft engines (jet engines) are a type of propulsion system commonly used in aviation. These engines operate on jet propulsion, where air is drawn into the engine, mixed with fuel, ignited, and then expelled at high speed to generate thrust. Jet engines are used in commercial and military aircraft, as well as helicopters.
While turbine aircraft engines offer higher efficiency and performance than their counterparts, there is still a need to improve efficiency and reduce fuel consumption and greenhouse gases. It’s estimated that jet engines account for over 2.5% of all CO2 emissions, and there are substantial …
  • College: College of Engineering (COE)
  • Inventors: Spens, Alexander; Bons, Jeffrey
  • Licensing Officer: Zinn, Ryan

Highly Efficient Light Olefin Selectivity & Production Process
TS-065422 — Light olefins, such as ethylene and propylene, are essential building blocks in the petrochemical industry and have a wide range of uses in various applications. The most common uses for olefins include polymers, chemical intermediates, solvents, rubber, and nanomaterials, among others.
Although Light olefins are used globally in many products, the catalytic processes to produce them are energy intensive with a large carbon footprint and the production of greenhouse gases and water pollution. As a result, substantial efforts are being made in the industry to develop more sustain…
  • College: College of Engineering (COE)
  • Inventors: Ozkan, Umit; Gunduz, Seval; Kim, Jaesung
  • Licensing Officer: Zinn, Ryan

Halbach Cladding Magnets for Friction Reduction in Magnetic Gears
TS-065418 — Traditional mechanical gears rely on physical teeth engagement to transfer motion and torque while magnetic gears use the repulsive or attractive forces between magnets to achieve the same goal. Magnetic gears have several advantages: low noise and vibration, reduced maintenance, and inherent overload protection. Magnetic gears are used in applications that require variable speed control and precise torque transmission, such as robotics, aircraft, and automation.
Although magnetic gears provide several advantages to their traditional mechanical counterparts, they suffer from torque transmission inefficiency due to end-effect loss, which occurs when the magnetic flux leaks axially into the surrounding air and fails to couple between the rotors. As industri…
  • College: College of Engineering (COE)
  • Inventors: Dapino, Marcelo; Losey, Bradley "Brad"; Nas, Ismail
  • Licensing Officer: Zinn, Ryan

Monolithically Integrated Tunnel Junction-Based GaN Light Emitting Transistors
TS-065398 — Emissive display technologies (e.g., OLEDs) are display technologies that emit light directly to produce images. Unlike reflective displays, which rely on external light sources, emissive displays generate light, resulting in vibrant and high-contrast visuals. These next-generation displays are used in several applications, including mobile devices, AV/VR headsets, and wearable devices.
Although emissive displays are integrated into many electronic devices, they face some challenges. One of the primary issues is the integration of LEDs and electronic drivers when scaling into mesa dimensions. The mesa is a crucial parameter in display manufacturing as it determines the size of th…
  • College: College of Engineering (COE)
  • Inventors: Rajan, Siddharth; Jamal-Eddine, Zane; Joishi, Chandan "Chandan"; Rahman, Sheikh Ifatur
  • Licensing Officer: Zinn, Ryan

Bio-Matched Horn: A Novel 1-9 GHz On-Body Antenna for Low-Loss Biomedical Telemetry with Implants
TS-065135 — The use of wearable health devices has more than tripled in recent years due to the ability of these products to collect health data to detect potential health events (e.g., heart attacks), manage chronic diseases, and track physical activity. Wearable technologies have been shown to decrease the nu…
  • College: College of Engineering (COE)
  • Inventors: Blauert, John; Kiourti, Asimina
  • Licensing Officer: Randhawa, Davinder

Environmental Damage Model for Predicting Mechanism Transition under Time-Dependent Crack Growth Conditions.
TS-065131
  • College: College of Engineering (COE)
  • Inventors: Viswanathan, Gopal; Mills, Michael; Mills, David
  • Licensing Officer: Randhawa, Davinder

Wearable Sensors for Touch-Based Collaboration and Digital Gaming
TS-064825 — he Need In today's fast-paced and interconnected world, seamless collaboration among individuals is crucial for driving productivity and innovation. Traditional methods of interaction often fall short in capturing the nuances of human collaboration, leading to inefficiencies and misunderstandin…
  • College: College of Engineering (COE)
  • Inventors: Kiourti, Asimina; King, Cameron; Swearingen, EunKyoung "Kyoung"; Swearingen, Scott; Thrane, Susan; Williamson, Ian
  • Licensing Officer: Panic, Ana

Survey for Doctoral Student Retention
TS-064746 — The Need: In today's competitive academic landscape, understanding and improving organizational climate are paramount for institutions striving to enhance student retention, particularly within the engineering department. However, existing instruments often overlook the nuanced experiences of u…
  • College: College of Engineering (COE)
  • Inventors: Aldridge, Julie
  • Licensing Officer: Dahlman, Jason "Jay"

Automatic Mechanical Assembly Loops/Stacks Detection
TS-064578 — This software solution revolutionizes the process of tolerance stack analysis in mechanical assemblies. It automatically detects and extracts tolerance stacks as the foundational step for precise tolerance analysis and schema generation.
This software solution revolutionizes the process of tolerance stack analysis in mechanical assemblies. It automatically detects and extracts tolerance stacks as the foundational step for precise tolerance analysis and schema generation. The Need Analyzing tolerance stacks in mechanical assembl…
  • College: College of Engineering (COE)
  • Inventors: Haghighi, Payam; Shah, Jami
  • Licensing Officer: Randhawa, Davinder

Stretchable Broad Impedance Bandwidth RFID Tag Antenna
TS-064336 — Introducing innovative stretchable RFID devices with a broad impedance bandwidth, addressing the critical limitations of existing RFID systems in environments with variable characteristics.
Current passive UHF RFID systems falter in environments with fluctuating pressure, stress, and temperature due to their sensitivity to antenna deformation caused by changes in dielectric constant. A pressing need exists for stretchable RFID devices capable of operating seamlessly in diverse condit…
  • College: College of Engineering (COE)
  • Inventors: Burkholder, Robert; Kiourti, Asimina; Shao, Shuai; Volakis, John
  • Licensing Officer: Zinn, Ryan

Variable Stiffness Robotic Gripper Based on Layer Jamming
TS-064318 — Introducing cutting-edge soft robotic grippers featuring variable stiffness through positive pressure layer jamming, revolutionizing object manipulation in diverse applications. For a closely related technology, please visit https://oied.osu.edu/find-technologies and type "T2020-092" in the search field.
Automation using robotics has taken many forms including, but not limited to, automotive manufacturing, transportation of good in shipping warehouses, and the delicate handling of wafers in semiconductor plants. In many of these applications grippers and end-of-arm-tools (EOAT’s) are incorpo…
  • College: College of Engineering (COE)
  • Inventors: Su, Haijun; Crowley, George; Zeng, Xianpai
  • Licensing Officer: Zinn, Ryan

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