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Sustainability-Aware Management of Autonomous Mobile Robot (AMR) Fleets
TS-068477 — The Need Autonomous Mobile Robots (AMRs) are critical to modern, highly automated environments, operating 24/7 to optimize tasks, increase throughput, and meet demanding operational requirements. However, most task allocation and charging solutions focus solely on maximizing performance metrics like…
  • College: College of Engineering (COE)
  • Inventors: Brocanelli, Marco
  • Licensing Officer: Randhawa, Davinder

A Method for Accurate Cross Band Channel Prediction
TS-068476 — The Need Modern wireless networks, including 5G and future 6G systems, rely heavily on accurate channel prediction to ensure efficient and reliable communication. Frequency Domain Duplexing (FDD) systems face challenges in accurately predicting downlink channels from uplink channels, particularly in…
  • College: College of Engineering (COE)
  • Inventors: Banerjee, Avishek; Parthasarathy, Srinivasan; Srinivasan, Kannan
  • Licensing Officer: Randhawa, Davinder

A Scalable Method for Minimizing Beam-Training Overhead in mmWave Communications
TS-068475 — The Need As mmWave technology becomes the backbone of 5G and other advanced communication systems, the demand for fast, reliable, and scalable beamforming solutions has surged. Traditional beam-training methods are computationally intensive and time-consuming, leading to delays in establishing high-…
  • College: College of Engineering (COE)
  • Inventors: Srinivasan, Kannan; Chen, Wei-Han; Liu, Xin; Parthasarathy, Srinivasan
  • Licensing Officer: Randhawa, Davinder

Passive Optical-to-RF Conversion for Secure Eavesdropping on Optical Wireless Communication Systems
TS-068474 — The Need As Optical Wireless Communication (OWC) systems become increasingly prevalent, there is a growing demand for innovative signal conversion techniques that enhance communication capabilities while addressing security vulnerabilities. Conventional methods of optical-to-RF signal conversion rel…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xin; Song, Guanqun; Zhu, Ting
  • Licensing Officer: Randhawa, Davinder

Method for developing thick β-Ga2O3 films on (001) Ga2O3 substrates using (AlxGa1-x)2O3 buffer layer
TS-068473 — The Need β-Ga2O3 has spurred substantial interest in semiconductors and transistors in high-power/high-frequency electronics and ultraviolet optoelectronics. However, there exists a critical challenge of growing high-quality, thick layers of gallium oxide (Ga2O3) on Ga2O3 substrates. Existing …
  • College: College of Engineering (COE)
  • Inventors: Zhao, Hongping; Meng, Lingyu; Yu, Dong Su
  • Licensing Officer: Randhawa, Davinder

Self-Calibration Technique for mmWave Antenna Arrays Based on Everyday Communication Behaviors
TS-068472 — The Need The increasing adoption of mmWave technologies in 5G, IoT, and other advanced communication networks highlights a critical need for cost-effective, efficient, and scalable antenna calibration solutions. Traditional calibration methods rely on expensive laboratory setups and specialized equi…
  • College: College of Engineering (COE)
  • Inventors: Srinivasan, Kannan; Chen, Wei-Han; Liu, Xin
  • Licensing Officer: Randhawa, Davinder

Organizational Innovation Accelerator Program
TS-068445 — In today’s fast-paced global economy, organizations must continually adapt to remain competitive. Yet, systemic barriers—both social and technical—frequently hinder innovation. High production pressure, limited opportunities for professional development, and reliance on third-par…
  • College: College of Engineering (COE)
  • Inventors: Maguire, Laura; Rayo, Michael
  • Licensing Officer: Zinn, Ryan

Joint Activity Testing (JAT): A Testing & Evaluation Methodology for Human-Machine Teams
TS-068443 — In high-stakes industries, the integration of humans and advanced automation systems demands evaluation methods that reliably predict performance under varying challenges. Current testing methods often focus on individual components, failing to assess how human-machine teams operate as a unit, par…
  • College: College of Engineering (COE)
  • Inventors: Morey, Dane; Rayo, Michael
  • Licensing Officer: Zinn, Ryan

Vision System Using MDP-Based Tracking for Automated Dimensional Analysis
TS-068440 — Accurate measurement of physical attributes, such as dimensions, alignments, and surface features, is essential for ensuring quality and consistency across industries. Traditional measurement methods, often reliant on manual tools and human oversight, are time-intensive, prone to errors, and lac…
  • College: College of Engineering (COE)
  • Inventors: Allen, Theodore; Rodriguezbuno, Ramiro; Zhang, Yifei
  • Licensing Officer: Zinn, Ryan

Wearable Coils for Monitoring Human Body Kinematics
TS-067943 — Monitoring human physiological functions and performance during real-time activities is becoming increasingly popular in sporting and healthcare environments. Many studies now suggest that the quantitative evaluation of kinetic parameters, joint range of motion, heart rate, and breathing rate can be…
  • College: College of Engineering (COE)
  • Inventors: Kiourti, Asimina; Mishra, Vigyanshu
  • Licensing Officer: Randhawa, Davinder

Non-Contact Magnetocardiography for Measuring Cognitive Workload
TS-067810 — Work environments and other brain-intensive activities impose high demands on the cognitive and cerebral resources required to process vast amounts of information. This high demand can expose individuals to cognitive overload, which can be dangerous for their health and lead to errors and accidents.…
  • College: College of Engineering (COE)
  • Inventors: Kiourti, Asimina; Zhu, Keren
  • Licensing Officer: Randhawa, Davinder

A Non-Destructive Quality Control Test for Organic Coatings in Food Can Applications
TS-067800 — This technology is an electrical impedance test (EIT) for evaluating the integrity of the enamel coating found on the interior surface of canned foods.
Fruits and vegetables used in canning are picked at peak freshness, ensuring the best flavor and nutrient quality. Because canning preserves nutrients, canned foods can be as nutritious as fresh and frozen foods. The amount of minerals, fat-soluble vitamins, protein, fat, and carbohydrates remains r…
  • College: College of Engineering (COE)
  • Inventors: Frankel, Gerald "Jerry"; Kosanam, Koushik
  • Licensing Officer: Zinn, Ryan

Neonatal Blood Vessel Locator for Vascular Access Procedures
TS-067796 — A handheld device for identifying preterm blood vessels in neonatal ICU.
Over 300,000 preterm births in the United States occur annually, representing 10.5% of all live births. Most preterm births occur spontaneously, but some result from medical conditions like infections or pregnancy complications requiring early labor induction or cesarean delivery. Common causes of p…
  • College: College of Engineering (COE)
  • Inventors: Metzler, Sandra; Bresolin, Alejandro; Crawford, Mackenzie; Fernandes, Siddharth; Hardin, Rene; Patel, Aarti; Richards, Hannah; Trainor, Dylan
  • Licensing Officer: Zinn, Ryan

Methods to produce high purity tritium gas
TS-067793 — The technology is a device and method for producing high purity tritium gas by irradiating a lithium composition within a gas cell that selectively allows tritium to diffuse while blocking other byproducts, ensuring efficient and direct collection of pure tritium without extensive purification. This system is designed to enhance the purity, efficiency, and scalability of tritium production for various industrial and research applications.
The production of high purity tritium gas is critical for applications in nuclear fusion, radioluminescent devices, and scientific research. Current methods for tritium production often result in contaminants like helium and other gases, requiring additional purification processes that are costly …
  • College: College of Engineering (COE)
  • Inventors: Cao, Lei Raymond; Van Zile, Matthew
  • Licensing Officer: Zinn, Ryan

Computational Design of Experiment Framework for Processing of Metal Alloys
TS-067792 — A software tool for optimizing the manufacturing process for metal alloys.
Metallic alloys are composed of a homogeneous mixture of two or more metals or of metals and nonmetal or metalloid elements to provide specific characteristics or structural properties. Alloys are used in many applications, such as aircraft, offshore drilling, automobiles, and others. Obtaining t…
  • College: College of Engineering (COE)
  • Inventors: Alexandrov, Boian; Forquer, Matthew; Jang, Eun; Luo, Yuxiang; Stewart, Jeffrey
  • Licensing Officer: Zinn, Ryan

A device for improving the breakdown performance of gallium oxide semiconductors
TS-067551 — Gallium Oxide (Ga2O3) is an inorganic compound with semi-conductivity properties (e.g., a large bandgap) that can be used for developing power electronics, UV photodetectors, solar cells, and sensors. βeta-Ga2O3, a polymorph, has a distinct advantage over other semiconductors that have high cri…
  • College: College of Engineering (COE)
  • Inventors: Dheenan, Ashok; Dhara, Sushovan; Rajan, Siddharth
  • Licensing Officer: Zinn, Ryan

Optimal and Pure Leaf Classification Trees for Machine Learning (ML) Decision-Making
TS-067550 — A method to improve the performance and accuracy of ML-based decision trees.
Decision trees are popular machine learning (ML) methods used in classification and regression problems, and they have numerous applications in the real world. Various industries use decision trees to help decide strategies, investments, and operations. In addition, they are used in healthcare to he…
  • College: College of Engineering (COE)
  • Inventors: Allen, Theodore; Arrey, Evelyn; Booth, Matthew; Liu, Enhao; Mashayekhi, Medhi
  • Licensing Officer: Zinn, Ryan

Method of repurposing spacecraft dust as an agricultural material
TS-067535 — The Need In future decades, more people than ever will be spending time in space. Current crop production systems onboard spacecraft are not self-sustainable, relying on fertilizer and substrate materials that must be launched from Earth. These resupply missions can cost thousands of dollars per po…
  • College: College of Engineering (COE)
  • Inventors: Nastasi, Nicholas; Dannemiller, Karen
  • Licensing Officer: Ashouripashaki, Mandana

AIDRIN (AI Data Readiness Inspector)
TS-067116 — AIDRIN (AI Data Readiness INspector) is a system designed to comprehensively evaluate datasets through a diverse range of metrics, giving an overall perspective on their readiness for AI applications.
In the contemporary digital landscape, the explosive growth in data generation has created a pressing need for efficient and scalable database systems. Traditional databases struggle with the increasing volume, variety, and velocity of data, leading to performance bottlenecks, high operational cos…
  • College: College of Engineering (COE)
  • Inventors: Byna, Suren; Hiniduma, Kaveen
  • Licensing Officer: Zinn, Ryan

Endoscopic additive manufacturing of conductors and wireless implants
TS-067045 — The Need Wireless implants with integrated antennas are highly desirable for diagnostic, therapeutic, and monitoring applications due to their ability to communicate directly with external devices. However, the need for major surgical incisions to implant these devices poses significant risks, incl…
  • College: College of Engineering (COE)
  • Inventors: Kiourti, Asimina; Dontha, Balaji; Hoelzle, David; Li, Jinghua; Moulod, Mohammad
  • Licensing Officer: Randhawa, Davinder

Novel Quantitative Method to Detect Mold Growth in Buildings
TS-066963 — The Need Exposure to mold in homes costs billions of dollars every year. Exposure is particularly harmful to the 8% of the United States population that suffers from asthma; a leading cause of disability in children. Currently, odor, visible mold growth, and dampness are the best indicators of mold…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Balasubrahmaniam, Neeraja; Bope, Ashleigh
  • Licensing Officer: Ashouripashaki, Mandana

Dust Analysis: A Novel Approach to Monitoring Viral Spread
TS-066962 — The Need Viral disease surveillance (e.g. influenza, SARS-CoV-2) in high-risk settings faces several challenges, such as asymptomatic carriers, incomplete reporting, resource limitations, and delayed diagnosis of traditional swab test methods. These challenges could allow a virus to silently spread…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Faith, Seth; Hull, Natalie; Nastasi, Nick; Renninger, Nicole
  • Licensing Officer: Ashouripashaki, Mandana

Smartphone Detection Kit for Airborne Formaldehyde and Allergens
TS-066960 — The Need Indoor air can be polluted by various sources, including building materials, furniture, cleaning products, and even people. Exposure to these resulting contaminants and allergens can lead to a variety of health problems, such as respiratory irritation, allergies, and even cancer. It is cur…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Parquette, Jonathan; Qin, Rongjun
  • Licensing Officer: Ashouripashaki, Mandana

Color Correction System for Accurate Colorimetric Smartphone Measurements
TS-066957 — The Need Colorimetric tests and remote image analysis are used in a wide range of industrial and medical applications. Digital image-based measurements made with smartphones are a promising platform to quantify colors at low cost, but suffer from inconsistency and errors caused by lens quality, sen…
  • College: College of Engineering (COE)
  • Inventors: Dannemiller, Karen; Panescu, Jenny; Qin, Rongjun; Song, Shuang; Zhang, Guixiang
  • Licensing Officer: Ashouripashaki, Mandana

Unveiling the Nanoscale: Breakthrough Analytical Speed of Real-Time Super-Resolution Microscopy and Beyond
TS-066926 — This Ohio State University software innovation offers groundbreaking analytical speed and automation of Single-Molecule Localization Microscopy (SMLM) as well as analysis of 3D data and images extending beyond the field of microscopy. Our technology offers real-time spatial analysis in continuous and discrete space, enabling unprecedented speed and efficiency in data processing that translates into faster decision-making, high-throughput screening capabilities, and broad applicability beyond traditional microscopy.
Single-molecule localization microscopy (SMLM) describes a family of fast-evolving, powerful imaging techniques that dramatically improve spatial resolution over standard, diffraction-limited microscopy techniques and can image biological structures at the molecular scale. SMLM can now be performe…
  • College: College of Engineering (COE)
  • Inventors: Soltisz, Andrew; Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

Humanized SSTR2 mAb and ADC to target SSTR2+ tumors
TS-066912 — Targeted humanized mAbs and ADCs for cancer treatment
The Liu Lab Dr. Xiaoguang “Margaret” Liu applies her industry experience (Lonza, Merck, and Life Technologies) in cell line and process development towards her lab’s focus on targeted anti-cancer therapies including monoclonal antibodies, antibody-drug conjugates, and gene therapi…
  • College: College of Engineering (COE)
  • Inventors: Liu, Xiaoguang "Margaret"; Zhou, Lufang
  • Licensing Officer: Schworer, Adam

Revolutionary Modular Nuclear Reactor Core for Space Exploration
TS-066252 — Rotating Fuel Core with Fuel Strip(s) ("ROFFUS") is an innovative modular nuclear reactor core designed to provide reliable and scalable power for advanced space missions.
Future space missions require dependable, high-output energy sources to support operations such as material processing, transportation, and thermal conditioning, particularly in challenging environments like the lunar poles where sunlight is scarce. This advanced nuclear reactor core features a…
  • College: College of Engineering (COE)
  • Inventors: Smidts, Carol; Aldemir, Tunc; Cao, Lei Raymond; Horack, John; Khafizov, Marat
  • Licensing Officer: Zinn, Ryan

BDAMPER: Advanced Application Software for Dynamic Analysis and Design of Friction Damper Structures
TS-066234 — In the realm of rotating machinery and structural engineering, the need to manage and mitigate vibrations is paramount. Excessive vibrations can lead to material fatigue, operational inefficiency, and catastrophic failures. Industries require a sophisticated, accurate, and versatile tool to design…
  • College: College of Engineering (COE)
  • Inventors: Menq, Chia-Hsiang; Yang, Been-Der
  • Licensing Officer: Zinn, Ryan

3D Object-based Segmentation-based Quantification of Spatial Protein Organization (OBS3D)
TS-066233 — Protein analysis is foundational to understanding human physiology and is helpful for basic research, diagnosis, guiding treatment, and monitoring of human disease. There are several widely used platforms for evaluating protein function. The primary tools used in protein analysis on cells and tissues include antibody/aptamer, fluorescent detection systems, and mass spectrometry.
Colocalization analysis is the current standard technique for assessing spatial association of co‐labeled proteins in cells using multicolor immunofluorescence images. However, these tools are limited because multiple antigens nearby exhibit overlapping staining, which leads to inaccurate analys…
  • College: College of Engineering (COE)
  • Inventors: Veeraraghavan, Rengasayee
  • Licensing Officer: Zinn, Ryan

Innovative Solutions for Cell Viability and Targeted Delivery
TS-066100 — Research tool to transfect cells ex vivo using electroporation through electrospun core-shell fibers for research applications
The Need: Conventional electroporation methods often result in low cell viability due to heat generation, especially when working with primary cells. These methods also face challenges with non-specific transport of molecules, high vector integration rates leading to mutagenesis, and inefficacy in …
  • College: College of Engineering (COE)
  • Inventors: Gallego Perez, Daniel; Das, Devleena; Duarte Sanmiguel, Silvia; Higuita Castro, Natalia
  • Licensing Officer: Willson, Christopher

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