Available Technologies
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Dual-payload Humanized Antibody-Drug Conjugate (DualADC) for targeted chemo-immunotherapy
TS-062822 — Humanized Antibody-drugs conjugate for chemo-immunotherapy of multiple cancer types
The Technology
Dr. Margaret Liu and colleagues have developed a dual-payload antibody-drug conjugate (DualADC) for chemo-immunotherapy utilizing a new humanized antibody that targets CD276, a surface receptor that is overexpressed in Triple-negative Breast Cancers (TNBCs), lung cancer (including non…
- College: College of Engineering (COE)
- Inventors: Liu, Xiaoguang "Margaret"; Zhou, Lufang
- Licensing Officer: Schworer, Adam
Preventative Human T-cell leukemia virus type 1 vaccine
TS-062421 — The Need: Addressing the Global HTLV-1 Epidemic with a Novel Vaccine
Human T cell leukemia virus type-1 (HTLV-1) is a significant global health concern, responsible for causing Adult T cell leukemia/lymphoma (ATLL) and human myelopathy/tropical spastic paraparesis (HAM/TSP). With over 10 million pe…
- College: College of Veterinary Medicine
- Inventors: Panfil, Amanda; Green, Patrick; Niewiesk, Stefan
- Licensing Officer: Dahlman, Jason "Jay"
MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Solid Cancers
TS-062318 — The Need
Cancer is a significant health problem and a leading cause of death in developed countries. Solid cancers, including prostate, breast, lung, stomach, colon, and pancreatic cancers, pose particularly challenging diagnostic and treatment obstacles. Early detection of these cancers is crucial…
- College: College of Medicine (COM)
- Inventors: Croce, Carlo; Calin, George; Volinia, Stefano
- Licensing Officer: Willson, Christopher
Live Attenuated Mumps Virus-Based SARS-CoV-2 Vaccines for Infants and Children
TS-062231 — The Need: Addressing the Urgent Need for a Safe and Effective SARS-CoV-2 Vaccine for Infants and Children
The ongoing pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has brought about significant economic, emotional, and public health challenges worldwide. The pressing dema…
- College: College of Veterinary Medicine
- Inventors: Li, Jianrong; Boyaka, Prosper; Lu, Mijia; Zhang, Yuexiu
- Licensing Officer: Dahlman, Jason "Jay"
Drug Delivery System for the Treatment of Neurological Diseases
TS-054464 — Novel drug delivery system that enables efficient transfer of FDA-approved drugs for the treatment of neurological injuries.
Traumatic brain and spinal cord injury cause devastating neurological deficits and long-term disability due to detrimental structural and functional alteration in neuronal circuits. Treatment of brain injury and neurological disorders has traditionally been challenging due to the inability to deli…
- College: College of Engineering (COE)
- Inventors: Lannutti, John; Fan, Fan; Tedeschi, Andrea
- Licensing Officer: Schultz, Teri
Novel Vaccine for Respiratory Syncytial Virus
TS-037299 — Recombinant vesicular stomatitis virus (rVSV) vaccines to fight against respiratory syncytial virus (RSV) infections.
The Need: Respiratory Syncytial Virus (RSV) is a major cause of infant hospitalization due to acute lower respiratory tract infections (ALRI) in children under 5 years of age globally, causing up to 200,000 deaths annually. RSV leads to significantly more hospitalizations than influenza in children …
- College: College of Veterinary Medicine
- Inventors: Niewiesk, Stefan; Binjawadagi, Basavaraj; Li, Jianrong; Peeples, Mark
- Licensing Officer: Dahlman, Jason "Jay"
